Sexual and reproductive health and rights knowledge, perceptions, and experiences of adolescent learners from three South African townships: qualitative findings from the Girls Ach... by Cecilia Milford, Saiqa Mullick, Melanie Pleaner, Alison Kutywayo, Nicolette Naidoo

“…Methods: The intervention was conducted in 13 secondary schools across Khayelitsha, Thembisa, and Soweto, South Africa. A baseline survey collected socio-demographic data prior to the intervention. …”
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Levels of physical activity in people with chronic pain by Romy Parker, Emma Bergman, Anelisiwe Mntambo, Shannon Stubbs, Matthew Wills

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A qualitative study to explore daily versus on-demand oral pre-exposure prophylaxis (PrEP) in young people from South Africa, Uganda and Zimbabwe by Janan Janine Dietrich, Nadia Ahmed, Gugulethu Tshabalala, Minju Wu, Mamakiri Mulaudzi, Stefanie Hornschuh, Millicent Atujuna, Richard Muhumuza, Andrew Sentoogo Ssemata, Lynda Stranix-Chibanda, Teacler Nematadzira, Linda-Gail Bekker, Neil Martinson, Janet Seeley, Julie Fox

“…<h4>Methods</h4> Purposive sampling was used to recruit participants from Soweto and Cape Town (South Africa), Wakiso district (Uganda) and Chitungwiza (Zimbabwe). …”
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A qualitative study to explore daily versus on-demand oral pre-exposure prophylaxis (PrEP) in young people from South Africa, Uganda and Zimbabwe. by Janan Janine Dietrich, Nadia Ahmed, Gugulethu Tshabalala, Minju Wu, Mamakiri Mulaudzi, Stefanie Hornschuh, Millicent Atujuna, Richard Muhumuza, Andrew Sentoogo Ssemata, Lynda Stranix-Chibanda, Teacler Nematadzira, Linda-Gail Bekker, Neil Martinson, Janet Seeley, Julie Fox

“…<h4>Methods</h4>Purposive sampling was used to recruit participants from Soweto and Cape Town (South Africa), Wakiso district (Uganda) and Chitungwiza (Zimbabwe). …”
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Contraception knowledge and uptake among in-school adolescents in three South African townships: Baseline findings from the Girls Achieve Power (GAP Year) Trial [version 2; peer re... by Saiqa Mullick, Melanie Pleaner, Alison Kutywayo, Khuthala Mabetha, Nicolette Naidoo, Mags Beksinska

“…Methods: A baseline cross sectional survey was conducted among 3432 grade 8s enrolled into the Girls Achieve Power (GAP Year) trial from 26 public high schools across three South African townships (Soweto, Thembisa and Khayelitsha) (2017 - 2018). An interviewer-led survey collected information on SRH knowledge and perceptions; an audio computer-assisted self-interviewing technique gathered SRH service uptake. …”
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Physical behaviors and their association with type 2 diabetes mellitus risk markers in urban South African middle-aged adults: an isotemporal substitutionapproach by Lisa K Micklesfield, Maphoko Masemola, Tinashe Chikowore, Julia H Goedecke, Soren Brage, Kate Westgate, Clement N Kufe, Melikhaya Soboyisi, Antonia Smith

“…Introduction To examine the associations between physical behaviors and type 2 diabetes mellitus (T2DM) risk markers in middle-aged South African men and women.Research design and methods This cross-sectional study included middle-aged men (n=403; age: median (IQR), 53.0 (47.8–58.8) years) and women (n=324; 53.4 (49.1–58.1) years) from Soweto, South Africa. Total movement volume (average movement in milli-g) and time (minutes/day) spent in different physical behaviors, including awake sitting/lying, standing, light intensity physical activity (LPA) and moderate-to-vigorous intensity physical activity (MVPA), were determined by combining the signals from two triaxial accelerometers worn simultaneously on the hip and thigh. …”
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Evaluation of a Text Messaging Intervention to Promote Preconception Micronutrient Supplement Use: Feasibility Study Nested in the Healthy Life Trajectories Initiative Study in Sou... by Larske M Soepnel, Michelle C McKinley, Sonja Klingberg, Catherine E Draper, Alessandra Prioreschi, Shane A Norris, Lisa J Ware

“…ObjectiveThis study aimed to evaluate the feasibility of an automated 2-way text messaging intervention nested in an ongoing preconception health trial, the Healthy Life Trajectories Initiative (HeLTI; HeLTI Bukhali) in Soweto, South Africa. Second, we aimed to evaluate the acceptability of a health promotion radio serial, which aired concurrently in the region. …”
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Association between fetal abdominal growth trajectories, maternal metabolite signatures early in pregnancy, and childhood growth and adiposity: prospective observational multinatio... by Villar, J, Ochieng, R, Gunier, RB, Papageorghiou, AT, Rauch, S, McGready, R, Gauglitz, JM, Barros, FC, Vatish, M, Fernandes, M, Zammit, V, Carrara, VI, Munim, S, Craik, R, Barsosio, HC, Carvalho, M, Berkley, JA, Ismail, LIC, Norris, SA, Tshivuila-Matala, COO, Nosten, F, Ohuma, EO, Stein, A, Lambert, A, Winsey, A, Uauy, R, Eskenazi, B, Bhutta, ZA, Kennedy, SH

“…</p> <p><strong>Methods:&nbsp;</strong>In the prospective, multinational, observational INTERBIO-21st fetal study, conducted in maternity units in Pelotas (Brazil), Nairobi (Kenya), Karachi (Pakistan), Soweto (South Africa), Mae Sot (Thailand), and Oxford (UK), we enrolled women (&ge;18 years, with a BMI of less than 35 kg/m², natural conception, and a singleton pregnancy) who initiated antenatal care before 14 weeks&rsquo; gestation. …”

Examining the referral of patients with elevated blood pressure to health resources in an under-resourced community in South Africa by Lia K. McNulty, Mark Stoutenberg, Andrea Kolkenbeck-Ruh, Amy Harrison, Thabiso Mmoledi, Daniel Katiyo, Mimi Mhlaba, Delisile Kubheka, Lisa J. Ware

“…Methods CHWs conducted home visits, which included BP screening and brief counseling, with community members in Soweto, South Africa. Participants with elevated (systolic BP: 121–139/ diastolic BP: 81–89 mmHg) or high (≥ 140/90 mmHg) BP were referred to either a local, community-based physical activity (PA) program managed by a non-governmental organization or local health clinics. …”
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The impact of HIV and ART exposure during pregnancy on fetal growth: a prospective study in a South African cohort by Asanda Mtintsilana, Shane A. Norris, Siphiwe N. Dlamini, Lukhanyo H. Nyati, David M. Aronoff, John R. Koethe, Jeffrey A. Goldstein, Alessandra Prioreschi

“…Methods This prospective cohort study included pregnant women living with HIV (WLWH, n = 122) and not living with HIV (WNLWH, n = 250) that underwent repeated ultrasonography during pregnancy, and at delivery, to determine fetal growth parameters in Soweto, South Africa. The size and the velocity of fetal growth measures (i.e., head and abdominal circumference, biparietal diameter, and femur length) were calculated using the Superimposition by Translation and Rotation. …”
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Using the COM-B model and Behaviour Change Wheel to develop a theory and evidence-based intervention for women with gestational diabetes (IINDIAGO) by Katherine Murphy, Jamie Berk, Lorrein Muhwava-Mbabala, Sharmilah Booley, Janetta Harbron, Lisa Ware, Shane Norris, Christina Zarowsky, Estelle V. Lambert, Naomi S. Levitt

“…The IINDIAGO study aims to develop and evaluate an intervention for disadvantaged GDM women attending three large, public-sector hospitals for antenatal care in Cape Town and Soweto, SA. This paper offers a detailed description of the development of a theory-based behaviour change intervention, prior to its preliminary testing for feasibility and efficacy in the health system. …”
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Prevalence and socio-demographic correlates of tobacco and alcohol use in four sub-Saharan African countries: a cross-sectional study of middle-aged adults by Palwende Romuald Boua, Cassandra Claire Soo, Cornelius Debpuur, Innocent Maposa, Shai Nkoana, Shukri F. Mohamed, Solomon Choma, Abraham Oduro, Gershim Asiki, Lisa K. Micklesfield, Francesc Xavier Gómez-Olivé, Hermann Sorgho, Sumaya Mall, Michèle Ramsay, as members of AWI-Gen and the H3Africa Consortium

“…Current alcohol consumption was higher in men, compared to women (60.3% vs 29.3%), and highest in men from Soweto (70.8%) and women from Nanoro (59.8%). The overall prevalence of problematic alcohol consumption among men was 18.9%, and women 7.3%. …”
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In vitro activity of ceftazidime-avibactam against clinical isolates of Enterobacterales and Pseudomonas aeruginosa from sub-Saharan Africa: ATLAS Global Surveillance Program 2017–... by Mark G. Wise, James A. Karlowsky, Meredith A. Hackel, Mohamed Amine Harti, Bontle M.E. Ntshole, Eva Njeri Njagua, Rita Oladele, Catherine Samuel, Shameema Khan, Jeannette Wadula, Warren Lowman, Busisani W. Lembede, Daniel F. Sahm

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Biochemical progression free and overall survival among Black men with stage IV prostate cancer in South Africa: Results from a prospective cohort study by Yoanna S. Pumpalova, Adarsh Ramakrishnan, Michael May, Audrey Pentz, Shauli Minkowitz, Sean Doherty, Elvira Singh, Wenlong Carl Chen, Timothy R. Rebbeck, Alfred I. Neugut, Maureen Joffe

“…Design, Setting, and Participants Men diagnosed with prostate cancer (3/22/2016–10/30/2020) at Chris Hani Baragwanath Academic Hospital in Soweto, Johannesburg, were recruited for the Men of African Descent with Cancer of the Prostate study. …”
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Streptococcus pneumoniae and other bacterial nasopharyngeal colonization seven years post-introduction of 13-valent pneumococcal conjugate vaccine in South African children by Sarah L. Downs, Courtney P. Olwagen, Lara Van Der Merwe, Susan A. Nzenze, Marta C. Nunes, Shabir A. Madhi

“…Methods: Nasopharyngeal swabs were collected from healthy children <60-month-old (n = 571) in 2018 (period-2) and compared with samples (n = 1135) collected during early PCV7-introduction (period-1, 2010-11) in an urban low-income setting (Soweto). Pneumococci were tested for using a multiplex quantitative-polymerase chain reaction serotyping reaction-set. …”
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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trialResearch in cont... by Carolina Herrera, Jennifer Serwanga, Laura Else, Lebina Limakatso, Daniel Opoka, Andrew S. Ssemata, Azure-Dee Pillay, Patricia Namubiru, Thabiso B. Seiphetlo, Geoffrey Odoch, Susan Mugaba, Portia Seatlholo, Amara Alieu, Sujan Dilly Penchala, Richard Muhumuza, Berenice Alinde, Stefan Petkov, Kyle O'Hagan, Christian Callebaut, Janet Seeley, Helen Weiss, Saye Khoo, Francesca Chiodi, Clive M. Gray, Pontiano Kaleebu, Emily L. Webb, Neil Martinson, Julie Fox, Nadia Ahmed, Berenice Alinde, Amara Alieu, Millicent Atujuna, Esther Awino, Linda-Gail Bekker, Christian Callebaut, Francesca Chiodi, Mike Chirenje, Janan Dietrich, Jeffrey Dorfman, Laura Else, Julie Fox, Clive Gray, Christian Holm Hansen, Carolina Herrera, Stefanie Hornschuh, Ayoub Kakande, Pontiano Kaleebu, Charles Kelly, Saye Khoo, Mamkiri Khunwane, Limaktso Lebina, Joseph Makhura, Nomvuyo Mangxilana, Neil Martinson, Susan Mugaba, Richard Muhumuza, Freddie Mukasa Kibengo, Gertrude Mutonyi, Lucia Mungate, Winnie Nabukeera, Rehema Nagawa, Phiona Nalubega, Patricia Namubiru, Stephen Nash, Denis Ndekezi, Teacler Nematadzira, Lumka Nobula, Kyle O'Hagan, Geoffrey Odoch, Daniel Opoka, Sujan Dilly Penchala, Stefan Petkov, Azure-Dee Pillay, Jim Rooney, Elzette Rousseau, Eugene Ruzagira, Alison Sango, Ntombexolo Seatlholo, Janet Seeley, Thabiso Seiphetlo, Jennifer Serwanga, Robin Shattock, Andrew S. Ssemata, Lynda Stranix-Chibanda, Gugulethu Tshabalala, Emily Webb, Helen Weiss

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Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease by Ulf Landmesser, Børge G Nordestgaard, Leslie Cho, Niels Eske Bruun, Sotirios Tsimikas, Stephen J Nicholls, A Michael Lincoff, Steven E Nissen, Eran Leitersdorf, Kathy Wolski, John Kastelein, Michael Blaha, Ryuichi Morishita, Junhao Liu, Brian Manning, Plamen Kozlovski, Anastasia Lesogor, Tom Thuren, Taro Shibasaki, Florin Matei, Fábio Serra Silveira, Andreas Meunch, Aysha Bada, Vinod Vijan

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Gender disparities in pulmonary hypertension at a tertiary centre in Cameroon by L N Aminde, A Dzudie, A P Kenge, J Ndjebet, S Mapoh, X Kuelang, F Kamdem, B H Mbatchou Ngahane, M-S Doualla, K B Ngu, K Sliwa, F Thienemann

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Experience on postmortem minimally invasive tissue sampling to ascertain the cause of death determination in South African children: A case for implementing as standard of care by J du Toit, K Storath, I Dunn, P Makekeng, M Moosa, K Mothibi, N Umuneza, C A Rees, D Blau, S Lala, Y Adam, S Velaphi, M Hale, P Swart, J Wadula, L Mothibi, A Wise, V Baba, P Jaglal, S Mahtab, S Madhi, Z Dangor

“…MITS proves a valid alternative to full diagnostic autopsies, especially in low- and middle-income countries. In Soweto, South Africa (SA), the Child Health and Mortality Prevention Surveillance (CHAMPS) programme has delineated over 1 000 child and stillbirth deaths since 2017. …”
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The development of a nurse-led preoperative anaesthesia screening tool by Delphi consensus by M B Nejthardt, P Alexandris, S Bechan, M F A Bijli, S Chetty, J M Dippenaar, M Gibbs, M Johnson, H Kluyts, R Llewellyn, M Motiang, P Mogane, P Motshabi, B Mrara, F Roodt, U Singh, S Spijkerman, E Turton, J van der Westhuizen, B Biccard

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