Identification of Y chromosomal material in turner syndrome by Fluorescence in Situ Hybridisation (FISH) by Reena Rahayu Md Zin, Sharifah Noor Akmal, Zubaidah Zakaria, Clarence, Ko Ching Huat, Siti Mariam Yusof, Julia Mohd Idris, Zarina Abdul Latif, Wu, Loo Ling, Wong, Ming

“…From this study, two out of eight patients with Turner syndrome were found to have the sex determining region on the Y chromosome (SRY) gene by FISH analysis. Our results showed that the rate of detection of mosaic cases in Turner syndrome was also increased to 88% after using the FISH technique. …”
Get full text

Gema alunan Surah Al-Insan di Pantai Timur by Rahayu, Mustafa

Get full text

Pesquisa de sequências do cromossoma Y em indivíduos com síndroma de Turner. by Lénia Ferrão, Maria Lurdes Lopes, Catarina Limbert, Bárbara Marques, Filomena Boieiro, Marisa Silva, Ramira Marques, João Lavinha, Amilcar Mota, João Gonçalves

“…However, the ring Y was positive for SRY, RPS4Y, AMGY, TSPY loci on the short arm, DYZ3 (centromere) and, sY85, DFFRY, GY6, sY87, sY113, sY119, sY122, sY126 and RBMY1 on the long arm. …”
Get full text

Study of sex determination in mice lacking candidate genes identified by human exome sequencing by Sagar, D

“…In XX embryos, in the absence of SRY, canonical WNT signals and FOXL2 cause granulosa cell specification and ovary development. …”

Characterization of SHH, SOX3, WNT3A and WNT9B Proteins in Human Non-Syndromic Cleft Lip and Palate Tissue by Mārtiņš Vaivads, Ilze Akota, Māra Pilmane

“…This study evaluates the presence and correlations of Sonic Hedgehog (SHH), SRY-Box Transcription Factor 3 (SOX3), Wingless-type Family Member 3A (WNT3A) and 9B (WNT9B) protein containing cells in different cleft tissue. …”
Get full text

SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21 by Dandan Yu, Zhigang Zhao, Li Wang, Shishi Qiao, Zhen Yang, Qiang Wen, Guanghui Zhu

“…SOX21-AS1 positively regulated its nearby gene SRY-box transcription factor 21 (SOX21) at post-transcriptional level. …”
Get full text

Differentiation of Human Mesenchymal Stem Cells from Wharton’s Jelly Towards Neural Stem Cells Using a Feasible and Repeatable Protocol by Ewa Kruminis-Kaszkiel, Adam Osowski, Ewa Bejer-Oleńska, Mariusz Dziekoński, Joanna Wojtkiewicz

“…Flow cytometry and immunocytochemistry confirmed the expression of neural markers: nestin, sex-determining region Y (SRY) box 1 and 2 (SOX1 and SOX2), microtubule-associated protein 2 (MAP2), and glial fibrillary acidic protein (GFAP). …”
Get full text

Promotive role of USP29-mediated deubiquitination in malignant proliferation of colorectal cancer cells via the KIAA1429/SOX8 axis by Juncai Li, Jianguo Yang, Zhenzhou Chen, Li Liu, Hao Wang, Qican Deng, Yajun Chen, Yong Que, Zhongxue Fu

“…First, upregulations of USP29, KIAA1429, and SRY-box transcription factor 8 (SOX8) were found in CRC tissues and cells through real-time quantitative polymerase chain reaction and Western blotting. …”
Get full text

Two Different Copy Number Variations of the SOX5 and SOX8 Genes in Yak and Their Association with Growth Traits by Zhilong Zhang, Min Chu, Qi Bao, Pengjia Bao, Xian Guo, Chunnian Liang, Ping Yan

“…CNV has been widely used in breeding for growth traits, meat production or quality, and coat color. SRY-like box genes (SOXs) are a class of transcription factors that play a regulatory role in cell fate specification and differentiation. …”
Get full text

Stem Cell Biomarkers and Tumorigenesis in Gastric Cancer by Kenly Wuputra, Chia-Chen Ku, Jia-Bin Pan, Chung-Jung Liu, Yi-Chang Liu, Shigeo Saito, Kohsuke Kato, Ying-Chu Lin, Kung-Kai Kuo, Te-Fu Chan, Inn-Wen Chong, Chang-Shen Lin, Deng-Chyang Wu, Kazunari K. Yokoyama

“…By contrast, Estrogen receptor 1 (eR1), Leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1), SRY (sex determining region Y)-box 2 (Sox2), and B lymphoma Mo-MLV insertion region 1 homolog (Bmi1) are rich in both the antrum and corpus regions. …”
Get full text

SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction by Jin-Woo Lee, Choon-Soo Lee, HyunJu Son, Jaewon Lee, Minjun Kang, Jinho Chai, Hyun-Jai Cho, Hyo-Soo Kim

“…Using RNA sequencing, promoter analyses, and a loss-of-function study in human PSCs, we discovered that SRY-box transcription factor 17 (SOX17) is an essential upstream factor of LPAR4 during cardiac differentiation. …”
Get full text

SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis by Elsie Place, Elizabeth Manning, Dong Won Kim, Arisa Kinjo, Go Nakamura, Kyoji Ohyama

“…Informed by pseudotime meta-analysis of recent scRNA-seq data, we use immunohistochemistry and multiplex in situ hybridisation to show that SOX2, SRY-Box transcription factor 9 (SOX9), PROX1, Islet1 (ISL1), and SOX11 are sequentially expressed over the course of POMC neurogenesis in the embryonic chick. …”
Get full text

Chronological Changes in the Expression and Localization of Sox9 between Achilles Tendon Injury and Functional Recovery in Mice by Genji Watanabe, Masahito Yamamoto, Shuichirou Taniguchi, Yuki Sugiyama, Hidetomo Hirouchi, Satoshi Ishizuka, Kei Kitamura, Toshihide Mizoguchi, Takashi Takayama, Katsuhiko Hayashi, Shinichi Abe

“…Sex-determining region Y-box transcription factor 9 (Sox9) is an SRY-related transcription factor with a DNA-binding domain and is an important control factor for cartilage formation. …”
Get full text

ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway by Seiji Sawai, Tsunao Kishida, Shin-ichiro Kotani, Shinji Tsuchida, Ryo Oda, Hiroyoshi Fujiwara, Kenji Takahashi, Osam Mazda, Yoshihiro Sowa

“…Meanwhile, expression of multipotent stem cell markers such as Sex-determining region Y- (SRY-) box 2 (Sox2) was upregulated during induction. …”
Get full text

SOX2‐positive retinal stem cells are identified in adult human pars plicata by single‐cell transcriptomic analyses by Xiaotang Wang, Wei Fan, Zongren Xu, Qi Zhang, Na Li, Ruonan Li, Guoqing Wang, Siyuan He, Wanqian Li, Dan Liao, Zhi Zhang, Nan Shu, Jiaxing Huang, Chenyang Zhao, Shengping Hou

“…We identified one subpopulation expressing SRY‐box transcription factor 2 (SOX2) as RSCs, which were present in the pars plicata of the adult human eye. …”
Get full text

Melatonin Promotes Antler Growth by Accelerating MT1-Mediated Mesenchymal Cell Differentiation and Inhibiting VEGF-Induced Degeneration of Chondrocytes by Xuyang Sun, Xiaoying Gu, Keke Li, Mengqi Li, Jingna Peng, Xinxin Zhang, Liguo Yang, Jiajun Xiong

“…In addition, treatment with vascular endothelial growth factor (VEGF) promoted chondrocytes degeneration by downregulating the expression of Col2a and Sox9 (SRY-Box Transcription Factor 9). MLT effectively inhibited VEGF-induced degeneration of antler chondrocytes by inhibiting the Signal transducers and activators of transcription 5/Interleukin-6 (STAT5/IL-6) pathway and activating the AKT/CREB (Cyclin AMP response-element binding protein) pathway dependent on Sox9 expression. …”
Get full text

The Interplay of WNT and PPARγ Signaling in Vascular Calcification by Stefan Reinhold, W. Matthijs Blankesteijn, Sébastien Foulquier

“…Notably, the actively regulated β-catenin-dependent and -independent WNT signals increase the osteochondrogenic transformation of VSMC through the up-regulation of the osteochondrogenic transcription factors SRY-box transcription factor 9 (SOX9) and runt-related transcription factor 2 (RUNX2). …”
Get full text

Single-cell analysis reveals the spatial-temporal expression of genes associated with esophageal malformations by Carlo Maj, Antonia Eberts, Johannes Schumacher, Pouria Dasmeh

“…Notably, members of the forkhead-box family of transcription factors, namely FOXF1, FOXC1, and FOXD1, as well as the SRY-box transcription factor, SOX2, demonstrate the most significant preferential expression in both mouse and human embryos. …”
Get full text

Conservation of Zebrafish MicroRNA-145 and Its Role during Neural Crest Cell Development by Tomás J. Steeman, Juan A. Rubiolo, Laura E. Sánchez, Nora B. Calcaterra, Andrea M. J. Weiner

“…By whole-mount in situ hybridization, changes in expression patterns of <i>col2a1a</i> and Sry-related HMG box (Sox) transcription factors <i>sox9a</i> and <i>sox9b</i> were observed in overexpressed miR-145 embryos. …”
Get full text

Oestrogen Activates the MAP3K1 Cascade and β-Catenin to Promote Granulosa-like Cell Fate in a Human Testis-Derived Cell Line by Melanie K. Stewart, Pascal Bernard, Ching-Seng Ang, Deidre M. Mattiske, Andrew J. Pask

“…In non-mammalian vertebrates, the presence or absence of oestrogen dictates gonad differentiation, while in mammals, this mechanism has been supplanted by the testis-determining gene <i>SRY</i>. Exogenous oestrogen can override this genetic trigger to shift somatic cell fate in the gonad towards ovarian developmental pathways by limiting the bioavailability of the key testis factor SOX9 within somatic cells. …”
Get full text