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Editorial: Integration of structural biology data in lead drug discovery and optimization
Published 2023-02-01Get full text
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183
Mechanisms of Action for Small Molecules Revealed by Structural Biology in Drug Discovery
Published 2020-07-01Subjects: Get full text
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184
Correlative Structural Biology: How to Investigate the Fine Details of Viral Structure
Published 2010-01-01Get full text
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185
Structural biology of the LRRK2 GTPase and Kinase domains: Implications for regulation
Published 2014-05-01Get full text
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186
Principles of protein structure: an established Internet-based course in structural biology
Published 2000-12-01Get full text
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187
Pharmacological Chaperones and Protein Conformational Diseases: Approaches of Computational Structural Biology
Published 2023-03-01Subjects: Get full text
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188
A structural biology approach to understand human lymphatic filarial infection.
Published 2014-02-01Get full text
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189
Data publication with the structural biology data grid supports live analysis
Published 2016-03-01Get full text
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190
Progress, Challenges and Opportunities of NMR and XL-MS for Cellular Structural Biology
Published 2024-02-01Get full text
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191
Mass Spectrometry and Structural Biology Techniques in the Studies on the Coronavirus-Receptor Interaction
Published 2020-09-01Get full text
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192
The Structural Biology of Eastern Equine Encephalitis Virus, an Emerging Viral Threat
Published 2021-07-01“…This review article summarizes recent advances in the structural biology of EEEV based mainly on single-particle cryogenic electron microscopy (cryoEM) structures. …”
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193
BioShell 3.0: Library for Processing Structural Biology Data
Published 2020-03-01Get full text
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194
Activation and regulation mechanisms of NOD-like receptors based on structural biology
Published 2022-09-01“…NLRs are involved in a variety of diseases, and their detailed activation mechanisms based on structural biology can aid in developing therapeutic agents in the future. …”
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195
Emerging Contributions of Solid-State NMR Spectroscopy to Chromatin Structural Biology
Published 2021-10-01“…Here, we focus on the emerging contributions of magic-angle spinning solid-state nuclear magnetic resonance spectroscopy (MAS NMR), a relative newcomer on the chromatin structural biology stage. Unique among structural biology techniques, MAS NMR is ideally suited to provide atomic level information regarding both the rigid and dynamic components of this complex and heterogenous biological polymer. …”
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Data publication with the structural biology data grid supports live analysis
Published 2017“…Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data.sbgrid.org), to preserve primary experimental data sets that support scientific publications. …”
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197
Recent advances in the production of proteins in insect and mammalian cells for structural biology.
Published 2010“…Escherichia coli remains the dominant expression system in structural biology with nearly 90% of the structures in the Protein Data Bank (PDB) derived from proteins produced in this bacterial host. …”
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198
Quantifying radiation damage in X-ray diffraction experiments in structural biology
Published 2016“…<p>Quantitative studies of global radiation damage are presented for two different types of experiments in structural biology: macromolecular crystallography (MX) and small angle X-ray scattering (SAXS)</p> <p>MX is the most common technique to elucidate the atomic resolution structures of biological macromolecules. …”
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Towards high-throughput in situ structural biology using electron cryotomography
Published 2020“…These advances will considerably decrease the amount of time and effort required for cryo-ET and sub-tomogram averaging, ushering in a new era of structural biology where in situ macromolecular structure determination will be routine.…”
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A structural biology perspective on bioactive small molecules and their plant targets.
Published 2011“…Structural biology efforts in recent years have generated numerous co-crystal structures of bioactive small molecules interacting with their plant targets. …”
Journal article