The rapid developments of membrane protein structure biology over the last two decades by Lan Guan

“…Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized the field. …”
Get full text

The molecular structure, biological roles, and inhibition of plant pathogenic fungal chitin deacetylases by Johannes Mapuranga, Jiaying Chang, Hao Li, Yingdan Zhang, Ruolin Li, Lulu Song, Na Zhang, Wenxiang Yang

Get full text

SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development by Mei-Yue Wang, Rong Zhao, Li-Juan Gao, Xue-Fei Gao, De-Ping Wang, Ji-Min Cao

Get full text

TET (Ten-eleven translocation) family proteins: structure, biological functions and applications by Xinchao Zhang, Yue Zhang, Chaofu Wang, Xu Wang

Get full text

Diterpenes Specially Produced by Fungi: Structures, Biological Activities, and Biosynthesis (2010–2020) by Fa-Lei Zhang, Tao Feng

“…In this review, we provide an overview about the structures, biological activities, evolution, organic synthesis, and biosynthesis of diterpenoids that have been specially produced by fungi from 2010 to 2020. …”
Get full text

Bicyclo [6.3.0] Undecane Sesquiterpenoids: Structures, Biological Activities, and Syntheses by Guo-Fei Qin, Hong-Bao Liang, Wen-Xiu Liu, Feng Zhu, Ping-Lin Li, Guo-Qiang Li, Jing-Chun Yao

Get full text

NMR spectroscopy explained : simplified theory, applications and examples for organic chemistry and structural biology / by 254716 Jacobsen, Neil E.

Atomic-Resolution Experimental Structural Biology and Molecular Dynamics Simulations of Hyaluronan and Its Complexes by Olgun Guvench

“…In addition to supplementing the experimental structural biology with computed dynamic and thermodynamic information, the molecular dynamics studies provide a wealth of atomic-resolution information on hyaluronan-containing systems for which there is no atomic-resolution structural biology either available or possible. …”
Get full text

Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach by Iskander Khusainov, Bulat Fatkhullin, Simone Pellegrino, Aydar Bikmullin, Wen-ti Liu, Azat Gabdulkhakov, Amr Al Shebel, Alexander Golubev, Denis Zeyer, Natalie Trachtmann, Georg A. Sprenger, Shamil Validov, Konstantin Usachev, Gulnara Yusupova, Marat Yusupov

Get full text

Post-Translational Modifications of G Protein–Coupled Receptors Revealed by Proteomics and Structural Biology by Bingjie Zhang, Shanshan Li, Wenqing Shui, Wenqing Shui

Get full text

Hands-on training in structural biology, a tool for sustainable development in Africa series 4 by Dinkorma T. Ouologuem, Fatoumata O. Maiga, Antoine Dara, Abdoulaye Djimdé, Daouda A. K. Traore, Emmanuel Nji

Subjects: Get full text

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases by Brian C. Monk, Mikhail V. Keniya

“…This review will describe how structural biology is providing information for the improvement and discovery of inhibitors targeting the essential fungal enzyme sterol 14α-demethylase.…”
Get full text

Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase by Thomas-O Peulen, Carola S Hengstenberg, Ralf Biehl, Mykola Dimura, Charlotte Lorenz, Alessandro Valeri, Julian Folz, Christian A Hanke, Semra Ince, Tobias Vöpel, Bela Farago, Holger Gohlke, Johann P Klare, Andreas M Stadler, Claus AM Seidel, Christian Herrmann

“…We apply neutron spin echo, X-ray scattering, fluorescence, and EPR spectroscopy as techniques for integrative dynamic structural biology to study the structural basis and mechanism of conformational transitions in the human GBP1 (hGBP1). …”
Get full text

Comprehensive Collection and Prediction of ABC Transmembrane Protein Structures in the AI Era of Structural Biology by Hedvig Tordai, Erzsebet Suhajda, Ian Sillitoe, Sreenath Nair, Mihaly Varadi, Tamas Hegedus

Get full text

Structural Biology-Based Exploration of Subtype-Selective Agonists for Peroxisome Proliferator-Activated Receptors by Hiroyuki Miyachi

Subjects: Get full text

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices by Eitan Lerner, Anders Barth, Jelle Hendrix, Benjamin Ambrose, Victoria Birkedal, Scott C Blanchard, Richard Börner, Hoi Sung Chung, Thorben Cordes, Timothy D Craggs, Ashok A Deniz, Jiajie Diao, Jingyi Fei, Ruben L Gonzalez, Irina V Gopich, Taekjip Ha, Christian A Hanke, Gilad Haran, Nikos S Hatzakis, Sungchul Hohng, Seok-Cheol Hong, Thorsten Hugel, Antonino Ingargiola, Chirlmin Joo, Achillefs N Kapanidis, Harold D Kim, Ted Laurence, Nam Ki Lee, Tae-Hee Lee, Edward A Lemke, Emmanuel Margeat, Jens Michaelis, Xavier Michalet, Sua Myong, Daniel Nettels, Thomas-Otavio Peulen, Evelyn Ploetz, Yair Razvag, Nicole C Robb, Benjamin Schuler, Hamid Soleimaninejad, Chun Tang, Reza Vafabakhsh, Don C Lamb, Claus AM Seidel, Shimon Weiss

Get full text

Artificial intelligence-driven drug repurposing and structural biology for SARS-CoV-2 by Kartikay Prasad, Vijay Kumar

“…It is envisioned that this study will provide AI/ML researchers and the wider community an overview of the current status of AI applications particularly in structural biology, drug repurposing, and development, and motivate researchers in harnessing AI potentials in the fight against COVID-19.…”
Get full text

Recent innovations in membrane-protein structural biology [version 1; referees: 3 approved] by James P Allen

Get full text

Integrative approaches in cryogenic electron microscopy: Recent advances in structural biology and future perspectives by Aneek Banerjee, Sayan Bhakta, Jayati Sengupta

Subjects: Get full text

Why we are made of proteins and nucleic acids: Structural biology views on extraterrestrial life by Shunsuke Tagami

“…This review summarizes recent findings on simple ancestral proteins, outlines the basic knowledge in textbooks, and discusses the generally required properties for biological molecules from structural biology viewpoints (e.g., restriction of shapes, and types of intra- and intermolecular interactions), leading to the conclusion that proteins and nucleic acids are at least one of the simplest (and perhaps very common) forms of catalytic and genetic biopolymers in the universe. …”
Get full text