Structural and mechanistic studies on γ-butyrobetaine hydroxylase. ‌ Leung, I, Krojer, T, Kochan, G, Henry, L, von Delft, F, Claridge, T, Oppermann, U, McDonough, M, Schofield, C

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PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase. ‌ Loenarz, C, Ge, W, Coleman, M, Rose, N, Cooper, C, Klose, R, Ratcliffe, P, Schofield, C

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Structural basis for substrate specificity in human monomeric carbonyl reductases. ‌ Pilka, E, Niesen, F, Lee, W, El-Hawari, Y, Dunford, J, Kochan, G, Wsol, V, Martin, H, Maser, E, Oppermann, U

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The centaurin gamma-1 GTPase-like domain functions as an NTPase. ‌ Soundararajan, M, Yang, X, Elkins, J, Sobott, F, Doyle, D

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Mechanism and substrate recognition of human holo ACP synthase. ‌ Bunkoczi, G, Pasta, S, Joshi, A, Wu, X, Kavanagh, K, Smith, S, Oppermann, U

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Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis. ‌ El-Hawari, Y, Favia, A, Pilka, E, Kisiela, M, Oppermann, U, Martin, H, Maser, E

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Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation. ‌ Rellos, P, Pike, A, Niesen, F, Salah, E, Lee, W, von Delft, F, Knapp, S

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Structural and functional characterization of the human protein kinase ASK1. ‌ Bunkoczi, G, Salah, E, Filippakopoulos, P, Fedorov, O, Müller, S, Sobott, F, Parker, S, Zhang, H, Min, W, Turk, B, Knapp, S

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Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation ‌ Bullock, A, Das, S, Debreczeni, J, Rellos, P, Fedorov, O, Niesen, F, Guo, K, Papagrigoriou, E, Amos, A, Cho, S, Turk, B, Ghosh, G, Knapp, S

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Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A ‌ Kochan, G, Pilka, E, von Delft, F, Oppermann, U, Yue, W

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Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. ‌ Fedorov, O, Huber, K, Eisenreich, A, Filippakopoulos, P, King, O, Bullock, A, Szklarczyk, D, Jensen, L, Fabbro, D, Trappe, J, Rauch, U, Bracher, F, Knapp, S

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Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases. ‌ Bunkoczi, G, Misquitta, S, Wu, X, Lee, W, Rojkova, A, Kochan, G, Kavanagh, K, Oppermann, U, Smith, S

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Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase ‌ Guo, K, Lukacik, P, Papagrigoriou, E, Meier, M, Lee, W, Adamski, J, Oppermann, U

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Structure and substrate specificity of the Pim-1 kinase ‌ Bullock, A, Debreczeni, J, Amos, A, Knapp, S, Turk, B

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