Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer by Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell

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Comparison of the dose escalation potential for two hypofractionated radiotherapy regimens for locally advanced pancreatic cancer by Jenny Bertholet, Arabella Hunt, Alex Dunlop, Thomas Bird, Robert A. Mitchell, Uwe Oelfke, Simeon Nill, Katharine Aitken

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Current Status and Future Directions of Immunotherapies in Soft Tissue Sarcomas by William G. J. Kerrison, Alexander T. J. Lee, Khin Thway, Robin L. Jones, Paul H. Huang

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Maskulinitet og troféjakt i Arktis by Lena Aarekol

“…Sutton himself goes in and out of the role of conqueror; he puts his trust in the Norwegian crew and highlights his recommendations for safety on such trips. …”
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Building the barricade—DIY slit lamp breath shield by Zakariya Jarrar, Steven Harsum, Clara Hoi Ka Wu

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Do shortcuts leave older patients short changed? The UK TOASTIE study by Nicolò Matteo Luca Battisti, Richard Simcock

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Evolution of complexity in the zebrafish synapse proteome by Àlex Bayés, Mark O. Collins, Rita Reig-Viader, Gemma Gou, David Goulding, Abril Izquierdo, Jyoti S. Choudhary, Richard D. Emes, Seth G. N. Grant

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Correspondence: SEMA4A variation and risk of colorectal cancer by Ben Kinnersley, Daniel Chubb, Sara E. Dobbins, Matthew Frampton, Stephan Buch, Maria N. Timofeeva, Sergi Castellví-Bel, Susan M. Farrington, Asta Forsti, Jochen Hampe, Kari Hemminki, Robert M. W. Hofstra, Emma Northwood, Claire Palles, Manuela Pinheiro, Clara Ruiz-Ponte, Clemens Schafmayer, Manuel R. Teixeira, Helga Westers, Tom van Wezel, D. Timothy Bishop, Ian Tomlinson, Malcolm G. Dunlop, Richard S. Houlston

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Effects of Respiratory Motion on Y-90 PET Dosimetry for SIRT by Matthew D. Walker, Jonathan I. Gear, Allison J. Craig, Daniel R. McGowan

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Paracoccus yeei as a cause of peritoneal dialysis peritonitis in the United Kingdom by Mauricio A. Arias, John Clark

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Activating Mutations and/or Expression Levels of Tyrosine Kinase Receptors GRB7, RAS, and BRAF in Testicular Germ Cell Tumors by Alan McIntyre, Brenda Summersgill, Hayley E. Spendlove, Robert Huddart, Richard Houlston, Janet Shipley

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A comparison of machine learning methods for predicting recurrence and death after curative-intent radiotherapy for non-small cell lung cancer: Development and validation of multiv... by Sumeet Hindocha, Thomas G. Charlton, Kristofer Linton-Reid, Benjamin Hunter, Charleen Chan, Merina Ahmed, Emily J. Robinson, Matthew Orton, Shahreen Ahmad, Fiona McDonald, Imogen Locke, Danielle Power, Matthew Blackledge, Richard W. Lee, Eric O. Aboagye

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Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes by Abhijit Anand Mohite, Rangarajan V. Prabhu, Thomas Ressiniotis

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Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer by Laura Cato, Antje Neeb, Adam Sharp, Victor Buzón, Scott B Ficarro, Linxiao Yang, Claudia Muhle-Goll, Nane C Kuznik, Ruth Riisnaes, Daniel Nava Rodrigues, Olivier Armant, Victor Gourain, Guillaume Adelmant, Emmanuel A Ntim, Thomas Westerling, David Dolling, Pasquale Rescigno, Ines Figueiredo, Friedrich Fauser, Jennifer Wu, Jaice T Rottenberg, Liubov Shatkina, Claudia Ester, Burkhard Luy, Holger Puchta, Jakob Troppmair, Nicole Jung, Stefan Bräse, Uwe Strähle, Jarrod A Marto, Gerd Ulrich Nienhaus, Bissan Al-Lazikani, Xavier Salvatella, Johann S de Bono, Andrew CB Cato, Myles Brown

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Believing in Better: How Aspirations and Academic Self-concept Shape Young People's Outcomes by Sammons, P, Toth, K, Sylva, K

“…<br/><br/> This report is the third in a series produced using EPPSE datai for the Sutton Trust and it explores students’ aspirations in relation to their views on the importance of getting a degree, their own university plans and their beliefs about their academic performance and abilities (described in this report as their ‘academic self-concept’). …”

A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management b... by Nick J. Battersby, Mit Dattani, Sheela Rao, David Cunningham, Diana Tait, Richard Adams, Brendan J. Moran, Shelize Khakoo, Paris Tekkis, Shahnawaz Rasheed, Alex Mirnezami, Philip Quirke, Nicholas P. West, Iris Nagtegaal, Irene Chong, Anguraj Sadanandam, Nicola Valeri, Karen Thomas, Michelle Frost, Gina Brown

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A radiomics-based decision support tool improves lung cancer diagnosis in combination with the Herder score in large lung nodulesResearch in context by Benjamin Hunter, Mitchell Chen, Prashanthi Ratnakumar, Esubalew Alemu, Andrew Logan, Kristofer Linton-Reid, Daniel Tong, Nishanthi Senthivel, Amyn Bhamani, Susannah Bloch, Samuel V. Kemp, Laura Boddy, Sejal Jain, Shafick Gareeboo, Bhavin Rawal, Simon Doran, Neal Navani, Arjun Nair, Catey Bunce, Stan Kaye, Matthew Blackledge, Eric O. Aboagye, Anand Devaraj, Richard W. Lee

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Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma by Sally L George, Federica Lorenzi, David King, Sabine Hartlieb, James Campbell, Helen Pemberton, Umut H Toprak, Karen Barker, Jennifer Tall, Barbara Martins da Costa, Marlinde L van den Boogaard, M Emmy M Dolman, Jan J Molenaar, Helen E Bryant, Frank Westermann, Christopher J Lord, Louis Chesler

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Characterisation of a Novel Cell Line (ICR-SS-1) Established from a Patient-Derived Xenograft of Synovial Sarcoma by William G. J. Kerrison, Jian Ning, Lukas Krasny, Amani Arthur, Nafia Guljar, Mark L. Elms, Amanda Swain, Robin L. Jones, Khin Thway, Paul H. Huang

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EasyPeasy parenting app: findings from an efficacy trial on parent engagement and school readiness skills by Jelley, F, Sylva, K, Karemaker, A