Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets by Susanne N. Wijesinghe, Amel Badoume, Dominika E. Nanus, Archana Sharma‐Oates, Hussein Farah, Michelangelo Certo, Fawzeyah Alnajjar, Edward T. Davis, Claudio Mauro, Mark A. Lindsay, Simon W. Jones

Subjects: Get full text

Single-cell profiling uncovers synovial fibroblast subpopulations associated with chondrocyte injury in osteoarthritis by Zezhong Liu, Zezhong Liu, Zezhong Liu, Yongqi Sun, Jiaoyi Pan, Kechun Guo, Zhi Tang, Xiaofeng Wang, Xiaofeng Wang

Subjects: Get full text

Defective T-Cell Apoptosis and T-Regulatory Cell Dysfunction in Rheumatoid Arthritis by Charles J. Malemud

Subjects: Get full text

Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets by Dominika E Nanus, Amel Badoume, Susanne N Wijesinghe, Andrea M Halsey, Patrick Hurley, Zubair Ahmed, Rajesh Botchu, Edward T Davis, Mark A Lindsay, Simon W Jones

Subjects: Get full text

The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts by Magnus Diller, Klaus Frommer, Berno Dankbar, Ingo Tarner, Marie-Lisa Hülser, Lali Tsiklauri, Rebecca Hasseli, Michael Sauerbier, Thomas Pap, Stefan Rehart, Ulf Müller-Ladner, Elena Neumann

Subjects: Get full text

Corrigendum: Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast by Anil K. Singh, Mahamudul Haque, Bhanupriya Madarampalli, Yuanyuan Shi, Benjamin J. Wildman, Abdul Basit, Sadik A. Khuder, Bhagwat Prasad, Quamarul Hassan, Madhu M. Ouseph, Salahuddin Ahmed, Salahuddin Ahmed

Subjects: Get full text

SLAMF8 promotes the proliferation and migration of synovial fibroblasts by regulating the ERK/MMPs signalling pathway by Jun Liu, Ying Huang, Jiashun Zeng, Changming Chen, Peiting Li, Qiaoyi Ning, Xianyue Guan, Long Li

Subjects: Get full text

Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast by Anil K. Singh, Mahamudul Haque, Bhanupriya Madarampalli, Yuanyuan Shi, Benjamin J. Wildman, Abdul Basit, Sadik A. Khuder, Bhagwat Prasad, Quamarul Hassan, Madhu M. Ouseph, Salahuddin Ahmed, Salahuddin Ahmed

Subjects: Get full text

Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis by Maria G. Ledesma-Colunga, Norma Adán, Georgina Ortiz, Mariana Solís-Gutiérrez, Fernando López-Barrera, Gonzalo Martínez de la Escalera, Carmen Clapp

Subjects: Get full text

KLF9 positively regulates TRIM33 to inhibit abnormal synovial fibroblast proliferation, migration as well as inflammation in rheumatoid arthritis by Dan Huang, Liju Tao, Xiuri Du

Subjects: Get full text

Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro by Inkyung Kang, Christian Hundhausen, Stephen P. Evanko, Prasanthi Malapati, Gail Workman, Christina K. Chan, Cliff Rims, Gary S. Firestein, David L. Boyle, Kevin M. MacDonald, Jane H. Buckner, Thomas N. Wight

Subjects: Get full text

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype by Manuel J. Del Rey, Álvaro Valín, Alicia Usategui, Sandra Ergueta, Eduardo Martín, Cristina Municio, Juan D. Cañete, Francisco J. Blanco, Gabriel Criado, José L. Pablos

Subjects: Get full text

Exosomes from the synovial microenvironment in joint homeostasis and osteoarthritis by Pooja N. Swami, Henintsoa Fanjaniaina Andriamifidy, Shabirul Haque, Timothy Reed, Azhar Khan, Daniel A. Grande

Subjects: Get full text

Components of the sympathetic nervous system as targets to modulate inflammation – rheumatoid arthritis synovial fibroblasts as neuron-like cells? by Xinkun Cheng, Torsten Lowin, Nadine Honke, Georg Pongratz

Subjects: Get full text

Rapamycin suppresses rheumatoid arthritis fibroblast synovial cell proliferation and induces apoptosis via the AKT/mTORC1 pathway by Shengxiao Zhang, Xiaorong Hu, Qinyi Su, Heyi Zhang, Ting Cheng, Jia Wang, Ruomeng Pei, Xin Li, Ruqi Zhang, Hongfang Shao, Caihong Wang, Xiaofeng Li

Subjects: Get full text

Minoxidil weakens newly synthesized collagen in fibrotic synoviocytes from osteoarthritis patients by Stefan Sarkovich, Peter P. Issa, Andrew Longanecker, Davis Martin, Kaitlyn Redondo, Patrick McTernan, Jennifer Simkin, Luis Marrero

Subjects: Get full text

Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an in vitro co-culture model by V Shang, J Li, CB Little, JJ Li

Subjects: Get full text

Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis by Cristina Manferdini, Yasmin Saleh, Paolo Dolzani, Elena Gabusi, Diego Trucco, Giuseppe Filardo, Gina Lisignoli

Subjects: Get full text

Anti-proliferation and anti-migration effects of an aqueous extract of Cinnamomi ramulus on MH7A rheumatoid arthritis-derived fibroblast-like synoviocytes through induction of apop... by Jia Liu, Qing Zhang, Ruo-Lan Li, Shu-Jun Wei, Yong-Xiang Gao, Li Ai, Chun-Jie Wu, Xu-Feng Pu

Subjects: Get full text

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis by Haruka Tsuchiya, Mineto Ota, Keishi Fujio

Subjects: Get full text