An efficient and green sonochemical synthesis of some new eco-friendly functionalized ionic liquids by Mouslim Messali

“…Considerable stress to replace a lot of volatile organic compounds which were used as solvents in synthetic organic chemistry has been done for many chemical industries. …”
Get full text

SÍNTESES TOTAIS NO BRASIL EMPREGANDO ACOPLAMENTOS CRUZADOS MEDIADOS POR PALÁDIO by Mauricio M. Victor, Gálber S. B. da Silva

“…We intended to thus create an account, although restricted to the use of palladium, showing the evolution and current state of art of Synthetic Organic Chemistry in Brazil, which has advanced and accept the challenge of total synthesis of increasingly complex molecules, registering growth and maturity of this area among Brazilian researchers.…”
Get full text

RATIONAL APPROACHES FOR ENGINEERING NOVEL FUNCTIONALITIES IN CARBON-CARBON BOND FORMING ENZYMES by Perrin Baker, Stephen Y.K. Seah

“…Enzymes that catalyze carbon-carbon bond formation can be exploited as biocatalyst for synthetic organic chemistry. However, natural enzymes frequently do not possess the required properties or specificities to catalyze industrially useful transformations. …”
Get full text

Identification and Characterization of (3Z):(2E)-Hexenal Isomerases from Cucumber by Eleni A. Spyropoulou, Henk L. Dekker, Luuk Steemers, Jan H. van Maarseveen, Chris G. de Koster, Michel A. Haring, Robert C. Schuurink, Silke Allmann

Get full text

Novel betulin derivatives as multidrug reversal agents targeting P-glycoprotein by Jerónimo Laiolo, Dafni G. Graikioti, Cecilia L. Barbieri, Mariana B. Joray, Antonia I. Antoniou, D. Mariano A. Vera, Constantinos M. Athanassopoulos, María C. Carpinella

Get full text

Practical Organic Chemistry at the University of Applied Science at Fribourg Le Laboratoire de Chimie Organique à I'EIA-FR by Jean-Marc Bourgeois

“…To motivate the students, we let them carry out their laboratory work like research projects in synthetic organic chemistry. To provide some guide lines, we propose the following general reaction scheme: 2,6-di-(hydroxymethyl)-phenols are prepared and, after dehydration, brought to reaction with nucleophiles such as alcohols or activated aromatics. …”
Get full text

Recent advancements in iodide/phosphine-mediated photoredox radical reactions by Tinglan Liu, Yu Zhou, Junhong Tang, Chengming Wang

“…Photoredox catalysis plays a crucial role in contemporary synthetic organic chemistry. Since the groundbreaking work of Shang and Fu on photocatalytic decarboxylative alkylations in 2019, a wide range of organic transformations, such as alkylation, alkenylation, cyclization, amination, iodination, and monofluoromethylation, have been progressively achieved using a combination of iodide and PPh3. …”
Get full text

Espectroscopia de Ressonância Magnética Nuclear de 13C no estudo de rotas biossintéticas de produtos naturais 13C Nuclear Magnetic Resonance spectroscopy in the studies of biosythe... by Fernando César de Macedo Júnior

“…<abstract language="eng">During the last five decades, as a result of an interaction between natural product chemistry, synthetic organic chemistry, molecular biology and spectroscopy, scientists reached an extraordinary level of comprehension about the natural processes by which living organisms build up complex molecules. …”
Get full text

Unconventional mechanism and selectivity of the Pd-catalyzed C–H bond lactonization in aromatic carboxylic acid by Li-Ping Xu, Shaoqun Qian, Zhe Zhuang, Jin-Quan Yu, Djamaladdin G. Musaev

“…Methods to functionalize inert C–H bonds are a critical focus of synthetic organic chemistry. In this work the authors use computations and experiments to uncover the mechanisms of palladium-catalysed C–H lactonizations in aromatic carboxylic acids, and explain the origin of an observed preference for functionalization of a C(sp3)–H bond over a C(sp2)–H bond in a recent report.…”
Get full text

<i>N</i>-Iodosuccinimide as a Precatalyst for Direct Cross-Coupling of Alcohols with <i>C</i>-Nucleophiles under Solvent-Free Reaction Conditions by Njomza Ajvazi, Stojan Stavber

“…C–C bond formation is one of the most important implements in synthetic organic chemistry. In pursuit of effective synthetic routes functioning under greener pathways to achieve direct C–C bond formation, we report <i>N</i>-iodosuccinimide (NIS) as the most effective precatalyst among the <i>N</i>-halosuccinimides (NXSs) for the direct cross-coupling of benzyl alcohols with C-nucleophiles under solvent-free reaction conditions (SFRC). …”
Get full text

Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation by Bo Yang, Shi-Jun Li, Yongdong Wang, Yu Lan, Shifa Zhu

“…Although hydrogen atom transfer is widely observed in synthetic organic chemistry, intramolecular hydrogen atom transfer between atoms separated by fewer than four bonds is kinetically slow. …”
Get full text

Kinetics and Optimization of the Photocatalytic Reduction of Nitrobenzene by Julia Patzsch, Benedict Berg, Jonathan Z. Bloh

“…Overall these results demonstrate that heterogeneous photocatalytic reactions can be very efficient and productive at the same time and may therefore present a powerful tool in synthetic organic chemistry.…”
Get full text

Applications of chiral spirocyclic phosphoric acid in the synthesis of natural products by Yang Fan

“…With a 10 years development, chiral spirocyclic phosphoric acids (SPAs) have attracted a substantial amount of attention from the synthetic organic chemistry community. This kind of small molecule organic catalysts has some advantages like easy to obtain, no transition metal and wide application range. …”
Get full text

Episodes from the Continuous Search for Solutions against Downy Mildew Diseases by Clemens Lamberth

“…Rarely used reactions, which have been applied within these projects, such as Seebach's variation of the Passerini reaction, the Bogert quinazoline synthesis and the carbonyldiimidazole-mediated Lossen rearrangement give proof of the significance of synthetic organic chemistry for modern crop protection. …”
Get full text

Do isolamento à síntese da convolutamidina A From the isolation to the synthesis of convolutamydine A by Rosângela B. Silva, José C. Torres, Simon J. Garden, Flavio de Almeida Violante, Michelle J. C. Rezende, Bárbara V. da Silva, Angelo C. Pinto

“…When bioactive substances are isolated in low yields, such as in the case of convolutamydine A, the use of synthetic organic chemistry to prepare larger quantities of these substances is necessary. …”
Get full text

Bioorthogonal organic chemistry in living cells: novel strategies for labeling biomolecules. by van Swieten, P, Leeuwenburgh, M, Kessler, B, Overkleeft, H

“…In addition, with the advances in biocompatible synthetic organic chemistry, a whole new field of opportunity has opened up, affording high diversity in the nature of the label as well as a choice of ligation reactions. …”

Identification of global inhibitors of cellular glycosylation by Daniel Madriz Sørensen, Christian Büll, Thomas D. Madsen, Erandi Lira-Navarrete, Thomas Mandel Clausen, Alex E. Clark, Aaron F. Garretson, Richard Karlsson, Johan F. A. Pijnenborg, Xin Yin, Rebecca L. Miller, Sumit K. Chanda, Thomas J. Boltje, Katrine T. Schjoldager, Sergey Y. Vakhrushev, Adnan Halim, Jeffrey D. Esko, Aaron F. Carlin, Ramon Hurtado-Guerrero, Roberto Weigert, Henrik Clausen, Yoshiki Narimatsu

Get full text

Study on UF PES Membranes Spray-Coated with Polymerizable Bicontinuous Microemulsion Materials for Low-Fouling Behavior by Sneha De, Jonathan Heer, Suwetha Sankar, Fabian Geiger, Ephraim Gukelberger, Francesco Galiano, Raffaella Mancuso, Bartolo Gabriele, Alberto Figoli, Jan Hoinkis

Get full text

Titanium Surface Modification for Implantable Medical Devices with Anti-Bacterial Adhesion Properties by Consuelo Celesti, Teresa Gervasi, Nicola Cicero, Salvatore Vincenzo Giofrè, Claudia Espro, Elpida Piperopoulos, Bartolo Gabriele, Raffaella Mancuso, Giovanna Lo Vecchio, Daniela Iannazzo

Get full text

Evolution versus Design: Template-Directed Self-Assembly of Peptides to Artificial Proteins (TASP) by Manfred Mutter, Gabriele Tuchscherer

“… Protein design and mimicry combines elements of synthetic organic chemistry with structural and functional aspects of biological relevance in a unique way. …”
Get full text