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Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Published 2020-07-01“…Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological activities. …”
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5-(1-(4-Hydroxy-6-methyl-2-oxo-2<i>H</i>-pyran-3-yl)-2-oxo-2-phenylethyl)-1,3-dimethylpyrimidine-2,4,6(1<i>H</i>,3<i>H</i>,5<i>H</i>)-trione
Published 2023-05-01“…Arylglyoxal monohydrates with two different carbonyl groups are well known as worthwhile synthons in organic synthesis. 2-Pyrone and pyrimidine-2,4,6-trione are versatile building blocks for the synthesis of key intermediates in synthetic organic chemistry as well as in medicinal chemistry. …”
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304
Carbene-catalyzed enantioselective access to bioactive dihydropyridazinones and atroposelective access to binaphthyl ligands
Published 2022“…Development of new methodology for quick access to important molecular motifs is a growing field of research in synthetic organic chemistry. In this aspect, N-heterocyclic carbene (NHC) has witnessed a significant achievement, specifically in asymmetric synthesis, in last two decades. …”
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Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents
Published 2022-01-01“…One-pot synthesis is widely considered an efficient approach in synthetic organic chemistry and has been used to synthesize some indole compounds. …”
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Geochemical and Photochemical Constraints on S[IV] Concentrations in Natural Waters on Prebiotic Earth
Published 2023-12-01“…Our work illustrates the synergy between planetary science, geochemistry and synthetic organic chemistry toward understanding the emergence and maintenance of life on early Earth.…”
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Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections
Published 2018“…Because building screening collections with improved performance depends on efficient use of synthetic organic chemistry resources, these studies illustrate an important quantitative framework to help prioritize choices made in building such collections. …”
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Synthesis and properties of novel polycyclic (Hetero)aromatic systems
Published 2020“…Therefore, various synthetic organic chemistry and material research groups have devoted a significant effort towards these structural scaffolds. …”
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Thesis-Doctor of Philosophy -
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Part I: Cobalt-catalyzed C–H benzylation of arenes. Part II: Hypervalent iodine-mediated rearrangement of propargylic alcohol
Published 2021“…In Chapter 3, a glimpse of the recent development of cyclic hypervalent iodine reagents and their applications in synthetic organic chemistry is described with special focus on the heteroaryl- and vinyl-benziodoxol(on)es. …”
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Thesis-Doctor of Philosophy -
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Flow Chemistry Guided by Computer-Aided Synthesis Planning
Published 2022“…Synthetic organic chemistry provides access to valuable materials and molecules that enable advancements across scientific disciplines. …”
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Thesis