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141
Recent advancements in iodide/phosphine-mediated photoredox radical reactions
Published 2023-11-01“…Photoredox catalysis plays a crucial role in contemporary synthetic organic chemistry. Since the groundbreaking work of Shang and Fu on photocatalytic decarboxylative alkylations in 2019, a wide range of organic transformations, such as alkylation, alkenylation, cyclization, amination, iodination, and monofluoromethylation, have been progressively achieved using a combination of iodide and PPh3. …”
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142
<i>N</i>-Iodosuccinimide as a Precatalyst for Direct Cross-Coupling of Alcohols with <i>C</i>-Nucleophiles under Solvent-Free Reaction Conditions
Published 2020-08-01“…C–C bond formation is one of the most important implements in synthetic organic chemistry. In pursuit of effective synthetic routes functioning under greener pathways to achieve direct C–C bond formation, we report <i>N</i>-iodosuccinimide (NIS) as the most effective precatalyst among the <i>N</i>-halosuccinimides (NXSs) for the direct cross-coupling of benzyl alcohols with C-nucleophiles under solvent-free reaction conditions (SFRC). …”
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143
Do isolamento à síntese da convolutamidina A From the isolation to the synthesis of convolutamydine A
Published 2008-01-01“…When bioactive substances are isolated in low yields, such as in the case of convolutamydine A, the use of synthetic organic chemistry to prepare larger quantities of these substances is necessary. …”
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144
Bioorthogonal organic chemistry in living cells: novel strategies for labeling biomolecules.
Published 2005“…In addition, with the advances in biocompatible synthetic organic chemistry, a whole new field of opportunity has opened up, affording high diversity in the nature of the label as well as a choice of ligation reactions. …”
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145
Identification of global inhibitors of cellular glycosylation
Published 2023-02-01Get full text
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146
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147
Titanium Surface Modification for Implantable Medical Devices with Anti-Bacterial Adhesion Properties
Published 2022-05-01Get full text
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148
Waste‐free oxidation of alcohols at the surface of catalytic electrodes: What is required for industrial uptake?
Published 2022-10-01“…We provide a critical insight on the economic, technological, and educational issues that, in our viewpoint, will drive the uptake of this eminently green and highly effective synthetic organic chemistry technology in the fine chemical and pharmaceutical industries.…”
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149
The Rainbow Arching over the Fluorescent Thienoviologen Mesophases
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150
Working at the interfaces of data science and synthetic electrochemistry
Published 2022-03-01“…Electrochemistry is quickly entering the mainstream of synthetic organic chemistry. The diversity of new transformations enabled by electrochemistry is to a large extent a consequence of the unique features and reaction parameters in electrochemical systems including redox mediators, applied potential, electrode material, and cell construction. …”
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151
Recent advances and prospects in the organocatalytic synthesis of quinazolinones
Published 2022-09-01“…The domain of synthetic organic chemistry has grown significantly over the past few decades for the construction of highly functionalized therapeutically potential complex molecular structures with the aid of small organic molecules by replacing transition-metal catalysis. …”
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152
Chiral Alkyl Halides: Underexplored Motifs in Medicine
Published 2016-11-01“…While alkyl halides are valuable intermediates in synthetic organic chemistry, their use as bioactive motifs in drug discovery and medicinal chemistry is rare in comparison. …”
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153
Catalytic Hydrofunctionalization Reactions of 1,3-Diynes
Published 2022-01-01“…Despite conjugated 1,3-diynes being considered key building blocks in synthetic organic chemistry, this particular class of alkynes has been much less employed in hydrofunctionalization reactions when compared to terminal or internal monoynes. …”
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154
Mechanistic Views on First-row Earth-Abundant Transition Metal Catalyzed Ullmann-type O-Arylation Reactions
Published 2023-04-01“… Transition metal-catalyzed reactions have attracted much attention in synthetic organic chemistry due to their important role in the formation of C-heteroatom bonds. …”
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155
Redox-Neutral Radical-Cation Reactions: Multiple Carbon–Carbon Bond Formations Enabled by Single-Electron Transfer
Published 2020-11-01“…These reactions demonstrate the power of electrosynthesis in the field of synthetic organic chemistry not only from the viewpoint of energy conversion but also from that of redox economy because four-, five-, and six-membered-ring skeletons are constructed without a change in oxidation state of the growing molecules in synthetic routes. …”
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156
Synthetic approaches to potent heterocyclic inhibitors of tuberculosis: A decade review
Published 2022-10-01“…As is well known, advances in synthetic organic chemistry have historically enabled the production of important life-saving medications that have had a tremendous impact on patients’ lives and health all over the world. …”
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157
Therapies from Thiopeptides
Published 2023-11-01“…True to the theme of this issue, “Organic Synthesis and Medicinal Chemistry: Two Inseparable Partners”, an important message is that the above advances would have never materialized without the support of curiosity-driven, academic synthetic organic chemistry: a beleaguered science that nonetheless has been—and continues to be—instrumental to progress in the biomedical field.…”
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158
Various Synthetic Pathways for the Synthesis of 3,4-Disubstituted Isoxazole by One Pot Multicomponent Reaction
Published 2020-12-01“…Especially 3– methyl–4-arylmethylene substituted isooxazole is used as a main constituent in synthetic organic chemistry. Various approaches have been made for diverse synthesis of 3,4-distituted isoxazoles via multicomponent reaction using different catalyst. …”
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159
Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Published 2000“…They reveal how CAS catalyzes formation of the clavam nucleus, via a process unprecedented in synthetic organic chemistry, and suggest how it discriminates between substrates and controls reaction of its highly reactive ferryl intermediate. …”
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160
Regioselective Reduction of 1<i>H</i>-1,2,3-Triazole Diesters
Published 2021-09-01“…Regioselective reactions can play pivotal roles in synthetic organic chemistry. The reduction of several 1-substituted 1,2,3-triazole 4,5-diesters by sodium borohydride has been found to be regioselective, with the C(5) ester groups being more reactive towards reduction than the C(4) ester groups. …”
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