Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid by Miro Julian Eigenmann, Tine Veronica Karlsen, Marek Wagner, Olav Tenstad, Tina Weinzierl, Tanja Fauti, Hans Peter Grimm, Trude Skogstrand, Christian Klein, Johannes Sam, Pablo Umana, Marina Bacac, Helge Wiig, Antje-Christine Walz

Subjects: “…T-cell bispecifics…”
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Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies by S Jordan Kerns, Chaitra Belgur, Debora Petropolis, Marianne Kanellias, Riccardo Barrile, Johannes Sam, Tina Weinzierl, Tanja Fauti, Anne Freimoser-Grundschober, Jan Eckmann, Carina Hage, Martina Geiger, Patrick Ray Ng, William Tien-Street, Dimitris V Manatakis, Virginie Micallef, Regine Gerard, Michael Bscheider, Ekaterina Breous-Nystrom, Anneliese Schneider, Anna Maria Giusti, Cristina Bertinetti-Lapatki, Heather Shannon Grant, Adrian B Roth, Geraldine A Hamilton, Thomas Singer, Katia Karalis, Annie Moisan, Peter Bruenker, Christian Klein, Marina Bacac, Nikolce Gjorevski, Lauriane Cabon

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A promising platform for predicting toxicity by Maria Ochoa de Olza

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Corrigendum: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity by Johannes Sam, Sara Colombetti, Tanja Fauti, Andreas Roller, Marlene Biehl, Linda Fahrni, Valeria Nicolini, Mario Perro, Tapan Nayak, Esther Bommer, Anne Schoenle, Maria Karagianni, Marine Le Clech, Nathalie Steinhoff, Christian Klein, Pablo Umaña, Marina Bacac

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Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity by Johannes Sam, Sara Colombetti, Tanja Fauti, Andreas Roller, Marlene Biehl, Linda Fahrni, Valeria Nicolini, Mario Perro, Tapan Nayak, Esther Bommer, Anne Schoenle, Maria Karagianni, Marine Le Clech, Nathalie Steinhoff, Christian Klein, Pablo Umaña, Marina Bacac

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Construction of tetravalent bispecific Tandab (CD3/BCMA)-secreting human umbilical cord mesenchymal stem cells and its efficiency in the treatment of multiple myeloma by Mengshang Xiong, Chunfang Kong, Yang Lu, Jiaojun Liu, Weirong Ding, Tingting Zhang, Wei Zuo, Lixia Cao, Qiling Lu, Anna Li, Chaoyu Li, Liting Ding, Yutao Yan, Bo Ke, Caishui Wan

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Format and geometries matter: Structure-based design defines the functionality of bispecific antibodies by Steffen Dickopf, Guy J. Georges, Ulrich Brinkmann

Subjects: “…T cell bispecific…”
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Logic-gated and contextual control of immunotherapy for solid tumors: contrasting multi-specific T cell engagers and CAR-T cell therapies by Olivier Nolan-Stevaux, Richard Smith

Subjects: “…T cell bispecific antibodies…”
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T Cell Bispecific Antibodies: An Antibody-Based Delivery System for Inducing Antitumor Immunity by Daisuke Kamakura, Ryutaro Asano, Masahiro Yasunaga

Subjects: “…T cell bispecific antibody…”
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Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils by Gabrielle Leclercq, Llucia Alberti Servera, Sabrina Danilin, John Challier, Nathalie Steinhoff, Claudia Bossen, Alex Odermatt, Valeria Nicolini, Pablo Umaña, Christian Klein, Marina Bacac, Anna-Maria Giusti, Anneliese Schneider, Hélène Haegel

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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors by Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom

Subjects: “…T cell bispecific…”
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Procollagen-lysine 2-oxoglutarate 5-dioxygenases are responsible for 5R-hydroxylysine modification of therapeutic T-cell bispecific monoclonal antibodies produced by Chinese hamste... by Niels Bauer, Niels Bauer, Marco Boettger, Styliani Papadaki, Tanja Leitner, Stefan Klostermann, Hubert Kettenberger, Guy Georges, Vincent Larraillet, Dino Gluhacevic von Kruechten, Lars Hillringhaus, Annette Vogt, Simon Ausländer, Oliver Popp

Subjects: “…T-cell bispecific monoclonal antibodies…”
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CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins by Christian Jost, Diana Darowski, John Challier, Vesna Pulko, Lydia J Hanisch, Wei Xu, Ekkehard Mössner, Alexander Bujotzek, Stefan Klostermann, Pablo Umana, Roland E. Kontermann, Christian Klein

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