ALS-linked TDP-43M337V knock-in mice exhibit splicing deregulation without neurodegeneration by Seiji Watanabe, Kotaro Oiwa, Yuri Murata, Okiru Komine, Akira Sobue, Fumito Endo, Eiki Takahashi, Koji Yamanaka

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TDP-43 and Phosphorylated TDP-43 Levels in Paired Plasma and CSF Samples in Amyotrophic Lateral Sclerosis by Yuting Ren, Yuting Ren, Siyuan Li, Siyu Chen, Xiaosun Sun, Xiaosun Sun, Fei Yang, Hongfen Wang, Mao Li, Fang Cui, Xusheng Huang

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TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43 by Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernández-Beltrán, Juan I. López-Carbonero, Pablo Bascuñana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñoz de Bustillo Alfaro, Maria J. Sánchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano

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Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo by Charlton G. Otte, Tyler R. Fortuna, Jacob R. Mann, Amanda M. Gleixner, Nandini Ramesh, Noah J. Pyles, Udai B. Pandey, Christopher J. Donnelly

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TDP-43 Pathology in Alzheimer’s Disease by Axel Meneses, Shunsuke Koga, Justin O’Leary, Dennis W. Dickson, Guojun Bu, Na Zhao

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The Role of TAR DNA Binding Protein 43 (TDP-43) as a CandiDate Biomarker of Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis by Caterina Maria Gambino, Anna Maria Ciaccio, Bruna Lo Sasso, Rosaria Vincenza Giglio, Matteo Vidali, Luisa Agnello, Marcello Ciaccio

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Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study by Oumayma Aousji, Simone Feldengut, Stefano Antonucci, Michael Schön, Tobias M. Boeckers, Jakob Matschke, Christian Mawrin, Albert C. Ludolph, Kelly Del Tredici, Francesco Roselli, Heiko Braak

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Conditioned Medium from Cells Overexpressing TDP-43 Alters the Metabolome of Recipient Cells by Rudolf Hergesheimer, Débora Lanznaster, Jérôme Bourgeais, Olivier Hérault, Patrick Vourc’h, Christian R. Andres, Philippe Corcia, Hélène Blasco

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RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy by Julie C Necarsulmer, Jeremy M Simon, Baggio A Evangelista, Youjun Chen, Xu Tian, Sara Nafees, Ariana B Marquez, Huijun Jiang, Ping Wang, Deepa Ajit, Viktoriya D Nikolova, Kathryn M Harper, J Ashley Ezzell, Feng-Chang Lin, Adriana S Beltran, Sheryl S Moy, Todd J Cohen

Subjects: “…TDP-43…”
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Maintaining the balance of TDP-43, mitochondria, and autophagy: a promising therapeutic strategy for neurodegenerative diseases by Chunhui Huang, Sen Yan, Zaijun Zhang

Subjects: “…TDP-43…”
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Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD by Tanzeen Yusuff, Tanzeen Yusuff, Ya-Chu Chang, Ya-Chu Chang, Tzu-Kang Sang, Tzu-Kang Sang, George R. Jackson, George R. Jackson, George R. Jackson, George R. Jackson, George R. Jackson, Shreyasi Chatterjee, Shreyasi Chatterjee, Shreyasi Chatterjee

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Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation by Nikita Fernandes, Luke Nero, Shawn M. Lyons, Pavel Ivanov, Telsa M. Mittelmeier, Timothy A. Bolger, J. Ross Buchan

Subjects: “…TDP-43…”
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Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis by Tatyana A. Shelkovnikova, Michail S. Kukharsky, Haiyan An, Pasquale Dimasi, Svetlana Alexeeva, Osman Shabir, Paul R. Heath, Vladimir L. Buchman

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Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1 by Katrin Hipke, Katrin Hipke, Bettina Pitter, Alexander Hruscha, Frauke van Bebber, Miha Modic, Miha Modic, Miha Modic, Vikas Bansal, Sebastian A. Lewandowski, Denise Orozco, Dieter Edbauer, Dieter Edbauer, Dieter Edbauer, Stefan Bonn, Christian Haass, Christian Haass, Christian Haass, Ulrich Pohl, Ulrich Pohl, Ulrich Pohl, Ulrich Pohl, Eloi Montanez, Bettina Schmid, Bettina Schmid

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Effect of icaritin on autophagy-related protein expression in TDP-43-transfected SH-SY5Y cells by Yanjun Zhou, Nanqu Huang, Yuanyuan Li, Zhisheng Ba, Yong Luo

Subjects: “…TDP-43…”
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Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD by Randall J. Eck, Paul N. Valdmanis, Nicole F. Liachko, Brian C. Kraemer

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Mechanisms of Neurosyphilis-Induced Dementia: Insights into Pathophysiology by Aya Fadel, Hussain Hussain, Robert J. Hernandez, Amanda Marie Clichy Silva, Amir Agustin Estil-las, Mohammad Hamad, Zahraa F. Saadoon, Lamia Naseer, William C. Sultan, Carla Sultan, Taylor Schnepp, Arumugam R. Jayakumar

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Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations by Skylar E. Davis, Anna K. Cook, Justin A. Hall, Yuliya Voskobiynyk, Nancy V. Carullo, Nicholas R. Boyle, Ahmad R. Hakim, Kristian M. Anderson, Kierra P. Hobdy, Derian A. Pugh, Charles F. Murchison, Laura J. McMeekin, Micah Simmons, Katherine A. Margolies, Rita M. Cowell, Alissa L. Nana, Salvatore Spina, Lea T. Grinberg, Bruce L. Miller, William W. Seeley, Andrew E. Arrant

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Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS by Febe Ferro, C. Roland Wolf, Christopher Henstridge, Francisco Inesta-Vaquera

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The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons by Daiyu Honda, Shinsuke Ishigaki, Yohei Iguchi, Yusuke Fujioka, Tsuyoshi Udagawa, Akio Masuda, Kinji Ohno, Masahisa Katsuno, Gen Sobue

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