TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation by Miguel Moutinho, Israel Coronel, Andy P. Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Brady K. Atwood, Shweta S. Puntambekar, Daniel C. Smith, Pablo Martinez, Seonggyun Han, Younghee Lee, Cristian A. Lasagna-Reeves, Bruce T. Lamb, Stephanie J. Bissel, Kwangsik Nho, Gary E. Landreth

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TREM2 Mediates Microglial Anti-Inflammatory Activations in Alzheimer’s Disease: Lessons Learned from Transcriptomics by Feng Xue, Heng Du

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sTREM2 Differentially Affects Cytokine Expression in Myeloid-Derived Cell Models via MAPK–JNK Signaling Pathway by Ryan Arsenault, Steven Marshall, Patrick Salois, Qiao Li, Wandong Zhang

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Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition by Brittani R. Price, Tiffany L. Sudduth, Erica M. Weekman, Sherika Johnson, Danielle Hawthorne, Abigail Woolums, Donna M. Wilcock

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Decoding sTREM2: its impact on Alzheimer’s disease – a comprehensive review of mechanisms and implications by Cui Lin, Yu Kong, Qian Chen, Jixiang Zeng, Xiaojin Pan, Jifei Miao

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Does Soluble TREM2 Protect Against Alzheimer's Disease? by Guy C. Brown, Peter St George-Hyslop, Peter St George-Hyslop

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Triggering Receptor Expressed on Myeloid Cells 2 Mediates the Involvement of M2-Type Macrophages in Pulmonary Tuberculosis Infection by Shang X, Maimaiti N, Fan J, Wang L, Wang Y, Sun H, Lv J, Zhang X, Wang J, Ma X

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TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers by Jorge L. Del-Aguila, Bruno A. Benitez, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Fabiana H. G. Farias, Maria Victoria Fernández, Laura Ibanez, Shan Jiang, Richard J. Perrin, Nigel J. Cairns, John C. Morris, Oscar Harari, Carlos Cruchaga

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The Pathogenesis in Alzheimer's Disease: TREM2 as a Potential Target by Guangtong Liu, Linlin Zhang, Yongzhao Fan, Wenliang Ji

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Functional insight into LOAD-associated microglial response genes by Lauren A. Jonas, Tanya Jain, Yue-Ming Li

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Regulation of microglia phagocytosis and potential involvement of exercise by Congqin Li, Yong Wang, Ying Xing, Jing Han, Yuqian Zhang, Anjing Zhang, Jian Hu, Yan Hua, Yulong Bai, Yulong Bai, Yulong Bai

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TREM2 Agonism with a Monoclonal Antibody Attenuates Tau Pathology and Neurodegeneration by Michael Fassler, Clara Benaim, Jacob George

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TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway by Yuan Li, Weihong Long, Menghan Gao, Fangtai Jiao, Zecai Chen, Mingyuan Liu, Lu Yu

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TREM2 Alleviates Neuroinflammation by Maintaining Cellular Metabolic Homeostasis and Mitophagy Activity During Early Inflammation by Lingfeng Hu, Jie Liu, Jie Peng, Xiao Li, Zhangqiong Huang, Caixing Zhang, Shengtao Fan

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THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency by Audrey Vautheny, Charlotte Duwat, Gwennaëlle Aurégan, Charlène Joséphine, Anne-Sophie Hérard, Caroline Jan, Julien Mitja, Pauline Gipchtein, Marie-Claude Gaillard, Luc Buée, David Blum, Philippe Hantraye, Gilles Bonvento, Emmanuel Brouillet, Karine Cambon, Alexis-Pierre Bemelmans

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Consecutive Injection of High-Dose Lipopolysaccharide Modulates Microglia Polarization via TREM2 to Alter Status of Septic Mice by Zhiyun Qiu, Huilin Wang, Mengdi Qu, Shuainan Zhu, Hao Zhang, Qingwu Liao, Changhong Miao

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EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway by Manuela Leri, Marzia Vasarri, Federica Carnemolla, Francesco Oriente, Serena Cabaro, Maria Stio, Donatella Degl’Innocenti, Massimo Stefani, Monica Bucciantini

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TREM2 risk variants and associated endophenotypes in alzheimer’s disease by Janna I. R. Dijkstra, Lisa Vermunt, Vikram Venkatraghavan, Georgii Ozhegov, Emma M. Coomans, Rik Ossenkoppele, Elsmarieke van de Giessen, Marc Hulsman, Christa M. de Geus, Wiesje M. van der Flier, Sietske A. M. Sikkes, Frederik Barkhof, Betty Tijms, Alida A. Gouw, Willem de Haan, Everard G. B. Vijverberg, Yolande A. L. Pijnenburg, Henne Holstege, Charlotte E. Teunissen, Sven J. van der Lee

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Targeted exome sequencing reveals homozygous TREM2 R47C mutation presenting with behavioral variant frontotemporal dementia without bone involvement by Ng, Adeline S. L., Tan, Yi Jayne, Yi, Zhao, Tandiono, Moses, Chew, Elaine, Dominguez, Jacqueline, Macas, Mabel, Ng, Ebonne, Hameed, Shahul, Ting, Simon, Tan, Eng King, Foo, Jia Nee, Kandiah, Nagaendran

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Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology by Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia-Chen Liu, Joshua Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, Fuyao Li, Kai Chen, Francis Shue, Maxwell V. Dacquel, John Fryer, Akhilesh Pandey, Na Zhao, Guojun Bu

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