TREM2 in Neurodegenerative Diseases by Taylor R. Jay, Victoria E. von Saucken, Gary E. Landreth

“…Abstract TREM2 variants have been identified as risk factors for Alzheimer’s disease (AD) and other neurodegenerative diseases (NDDs). …”
Get full text

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers by Nicholas J. Ashton, Marc Suárez-Calvet, Amanda Heslegrave, Abdul Hye, Cristina Razquin, Pau Pastor, Raquel Sanchez-Valle, José L. Molinuevo, Pieter Jelle Visser, Kaj Blennow, Angela K. Hodges, Henrik Zetterberg

Subjects: Get full text

TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation by Miguel Moutinho, Israel Coronel, Andy P. Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Brady K. Atwood, Shweta S. Puntambekar, Daniel C. Smith, Pablo Martinez, Seonggyun Han, Younghee Lee, Cristian A. Lasagna-Reeves, Bruce T. Lamb, Stephanie J. Bissel, Kwangsik Nho, Gary E. Landreth

Subjects: “…TREM2…”
Get full text

Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology by Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia-Chen Liu, Joshua Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, Fuyao Li, Kai Chen, Francis Shue, Maxwell V. Dacquel, John Fryer, Akhilesh Pandey, Na Zhao, Guojun Bu

Subjects: “…Trem2 H157Y mutation…”
Get full text

The therapeutic potential of TREM2 in cancer by Elysa M. Wolf, Barbara Fingleton, Alyssa H. Hasty, Alyssa H. Hasty

Subjects: “…TREM2 (triggering receptor expressed on myeloid cells 2)…”
Get full text

Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology by Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia-Chen Liu, Joshua Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, Fuyao Li, Kai Chen, Francis Shue, Maxwell V. Dacquel, John Fryer, Akhilesh Pandey, Na Zhao, Guojun Bu

Get full text

Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice by Vaishnavi S. Jadhav, Peter B. C. Lin, Taylor Pennington, Gonzalo Viana Di Prisco, Asha Jacob Jannu, Guixiang Xu, Miguel Moutinho, Jie Zhang, Brady K. Atwood, Shweta S. Puntambekar, Stephanie J. Bissel, Adrian L. Oblak, Gary E. Landreth, Bruce T. Lamb

Subjects: Get full text

Function and mechanism of TREM2 in bacterial infection. by Zehua Wu, Shiyue Yang, Xiangming Fang, Qiang Shu, Qixing Chen

“…We further illustrate the role of TREM2 in restoring organ homeostasis in sepsis and soluble TREM2 (sTREM2) as a diagnostic marker for sepsis-associated encephalopathy (SAE). …”
Get full text

Function and mechanism of TREM2 in bacterial infection by Zehua Wu, Shiyue Yang, Xiangming Fang, Qiang Shu, Qixing Chen

Get full text

TREM2 as an evolving therapeutic target in Alzheimer’s disease by Jacob George

Get full text

Plasmonic Interferometers as TREM2 Sensors for Alzheimer’s Disease by Dingdong Li, Rachel Odessey, Dongfang Li, Domenico Pacifici

Subjects: “…TREM2 sensors…”
Get full text

TREM2 regulates innate immunity in Alzheimer’s disease by Jiang-Tao Li, Ying Zhang

Subjects: “…Triggering receptor expressed on myeloid cells 2 (TREM2)…”
Get full text

Exploring the Impact of TREM2 in Tumor-Associated Macrophages by Darya Khantakova, Simone Brioschi, Martina Molgora

Subjects: “…TREM2…”
Get full text

The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans by Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers, Kaichuan Zhu, Anna Mallach, Bettina Brunner, Gernot Kleinberger, Wilbur Song, Marco Colonna, Jochen Herms, Wolfgang Wurst, Jennifer M. Pocock, Christian Haass

Subjects: Get full text

TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer’s Disease by Francesca La Rosa, Simone Agostini, Federica Piancone, Ivana Marventano, Ambra Hernis, Chiara Fenoglio, Daniela Galimberti, Elio Scarpini, Marina Saresella, Mario Clerici

Subjects: Get full text

TREM2 coding variants in Slovak Alzheimer's disease patients by Vladimira Durmanova, Juraj Javor, Zuzana Parnicka, Gabriel Minarik, Agata Ocenasova, Barbora Vaseckova, Iliana Kiralyova, Stanislav Sutovsky, Robert Petrovic, Ivana Shawkatova

Subjects: Get full text

The Pathogenesis in Alzheimer's Disease: TREM2 as a Potential Target by Guangtong Liu, Linlin Zhang, Yongzhao Fan, Wenliang Ji

Subjects: Get full text

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance by Xianyuan Xiang, Georg Werner, Bernd Bohrmann, Arthur Liesz, Fargol Mazaheri, Anja Capell, Regina Feederle, Irene Knuesel, Gernot Kleinberger, Christian Haass

Subjects: Get full text

The role of TREM2 in Alzheimer’s disease: from the perspective of Tau by Wendi Huang, Juan Huang, Nanqu Huang, Yong Luo

Subjects: Get full text

Function of TREM1 and TREM2 in Liver-Related Diseases by Huifang Sun, Jianguo Feng, Liling Tang

Subjects: Get full text