DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses—Inflammations and Cancers Can Have High Genomic Risks by Huihong Zeng, Gayani K. Nanayakkara, Gayani K. Nanayakkara, Ying Shao, Ying Shao, Hangfei Fu, Hangfei Fu, Yu Sun, Yu Sun, Ramon Cueto, Ramon Cueto, William Y. Yang, William Y. Yang, Qian Yang, Qian Yang, Qian Yang, Haitao Sheng, Haitao Sheng, Haitao Sheng, Na Wu, Na Wu, Na Wu, Luqiao Wang, Luqiao Wang, Luqiao Wang, Wuping Yang, Hongping Chen, Lijian Shao, Jianxin Sun, Xuebin Qin, Joon Y. Park, Konstantinos Drosatos, Konstantinos Drosatos, Eric T. Choi, Eric T. Choi, Qingxian Zhu, Hong Wang, Hong Wang, Xiaofeng Yang, Xiaofeng Yang

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Catheter-Directed Thrombolysis of Iliocaval Thrombosis in Patients With COVID-19 Infection by Mohamad Al-Otaibi, MD, Omer Iftikhar, MD, Yevgeniy Brailovsky, DO, MSc, Parth Rali, MD, Sabrina Islam, MD, MPH, Erin Narewski, DO, Eric Choi, MD, Gary Cohen, MD, Riyaz Bashir, MD, Vladimir Lakhter, DO

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Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury by Bin Xu, Dongsun Park, Yosuke Ohtake, Hui Li, Umar Hayat, Junjun Liu, Michael E. Selzer, Frank M. Longo, Shuxin Li

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Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord by Jinbin Zhai, Hyukmin Kim, Seung Baek Han, Meredith Manire, Rachel Yoo, Shuhuan Pang, George M Smith, Young-Jin Son

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Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice by Prasanta K. Dash, Rafal Kaminski, Ramona Bella, Hang Su, Saumi Mathews, Taha M. Ahooyi, Chen Chen, Pietro Mancuso, Rahsan Sariyer, Pasquale Ferrante, Martina Donadoni, Jake A. Robinson, Brady Sillman, Zhiyi Lin, James R. Hilaire, Mary Banoub, Monalisha Elango, Nagsen Gautam, R. Lee Mosley, Larisa Y. Poluektova, JoEllyn McMillan, Aditya N. Bade, Santhi Gorantla, Ilker K. Sariyer, Tricia H. Burdo, Won-Bin Young, Shohreh Amini, Jennifer Gordon, Jeffrey M. Jacobson, Benson Edagwa, Kamel Khalili, Howard E. Gendelman

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Incorporation of paclitaxel in mesenchymal stem cells using nanoengineering upregulates antioxidant response, CXCR4 expression and enhances tumor homing by Swayam Prabha, Carmen Merali, Drishti Sehgal, Emmanuelle Nicolas, Nitu Bhaskar, Magda Flores, Shubhmita Bhatnagar, Susheel Kumar Nethi, Carlos A. Barrero, Salim Merali, Jayanth Panyam

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The generative capacity of probabilistic protein sequence models by Francisco McGee, Sandro Hauri, Quentin Novinger, Slobodan Vucetic, Ronald M. Levy, Vincenzo Carnevale, Allan Haldane

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Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease by Pooja Jadiya, Devin W. Kolmetzky, Dhanendra Tomar, Antonio Di Meco, Alyssa A. Lombardi, Jonathan P. Lambert, Timothy S. Luongo, Marthe H. Ludtmann, Domenico Praticò, John W. Elrod

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1002 Bacterial amyloid curli/eDNA complexes induce NETosis in lupus patients positive for anti-dsDNA by Roberto Caricchio, Xinyan Zhang, Stefania Gallucci, Laurie Kilpatrick, Çagla Tükel, Ryan J Pachucki, Lynne Kohler, Sarah Tursi, Lauren Nicastro

Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells by Brittany Bodnar, Brittany Bodnar, Yongang Zhang, Yongang Zhang, Yongang Zhang, Jinbiao Liu, Yuan Lin, Yuan Lin, Peng Wang, Zhengyu Wei, Zhengyu Wei, Sami Saribas, Sami Saribas, Yuanjun Zhu, Yuanjun Zhu, Fang Li, Fang Li, Xu Wang, Wenli Yang, Qingsheng Li, Wen-Zhe Ho, Wenhui Hu, Wenhui Hu

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Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study by Luqiao Wang, Hangfei Fu, Gayani Nanayakkara, Yafeng Li, Ying Shao, Candice Johnson, Jiali Cheng, William Y. Yang, Fan Yang, Muriel Lavallee, Yanjie Xu, Xiaoshu Cheng, Hang Xi, Jonathan Yi, Jun Yu, Eric T. Choi, Hong Wang, Xiaofeng Yang

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PC19. FIBRIN SEALANTS DO NOT REDUCE THE RATE OF SEROMA FORMATION IN POST-MASTECTOMY BREAST RECONSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS by Karen E M Massada, MD, Meagan Wu, MA, Theresa K. Webster, BS, Juliet Panichella, BS, Michael C. Coronado, BS, Lindsay Talemal, BS, Nicholas Elmer, BS, Sthefano Araya, MD, Sthefano Araya, MD, Rohan Brebion, MD, Pablo A. Baltodano, MD, Sameer A. Patel, MD

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Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity by Shan He, Yongnian Liu, Lijun Meng, Hongxing Sun, Ying Wang, Yun Ji, Janaki Purushe, Pan Chen, Changhong Li, Jozef Madzo, Jean-Pierre Issa, Jonathan Soboloff, Ran Reshef, Bethany Moore, Luca Gattinoni, Yi Zhang

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Improving cellular phylogenies through the integrated use of mutation order and optimality principles by Sayaka Miura, Tenzin Dolker, Maxwell Sanderford, Sudhir Kumar

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Atrial Fibrillation Triggered by Premature Ventricular Complexes by Matthew Bocchese, MD, Hardik Mangrolia, MD, Anuj Basil, MD, Chethan Gangireddy, MD, Edmond Cronin, MD, George A. Yesenosky, MD, Richard M. Greenberg, MD, Joshua M. Cooper, MD, Isaac R. Whitman, MD

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Editorial: Sex differences and cardiovascular therapeutics by Fatma Saaoud, Keman Xu, Yifan Lu, Ying Shao, Xiaohua Jiang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang, Xiaofeng Yang

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Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis by Hangfei Fu, Yu Sun, Ying Shao, Jason Saredy, Ramon Cueto, Lu Liu, Charles Drummer, Candice Johnson, Keman Xu, Yifan Lu, Xinyuan Li, Shu Meng, Eric R. Xue, Judy Tan, Nirag C. Jhala, Daohai Yu, Yan Zhou, Kayla J. Bayless, Jun Yu, Thomas J. Rogers, Wenhui Hu, Nathaniel W. Snyder, Jianxin Sun, Xuebin Qin, Xiaohua Jiang, Xiaohua Jiang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang, Xiaofeng Yang, Xiaofeng Yang

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Smart dental materials for antimicrobial applications by Carolina Montoya, Lina Roldan, Michelle Yu, Sara Valliani, Christina Ta, Maobin Yang, Santiago Orrego

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Biology is Destiny: A Case of Adrenocortical Carcinoma Diagnosed and Resected at Inception in a Patient Under Close Surveillance for Lung Cancer by Benjamin Miron, Benjamin T. Ristau, Jeffrey J. Tomaszewski, Josh Jones, Bart Milestone, Yu-Ning Wong, Robert G. Uzzo, Donna Edmondson, Walter Scott, Alexander Kutikov

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Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach by Jay G. Fuletra, Benjamin T. Ristau, Barton Milestone, Harry S. Cooper, Alysia Browne, Sujana Movva, Thomas J. Galloway, Randall Lee, Nikhil Waingankar, Alexander Kutikov

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