Fast and Ultrasensitive Electrochemical Detection for Antiviral Drug Tenofovir Disoproxil Fumarate in Biological Matrices by Jingyun Xiao, Shuting Shi, Liangyuan Yao, Jinxia Feng, Jinsong Zuo, Quanguo He

Subjects: “…Tenofovir disoproxil fumarate…”
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298 Identifying vaginal microbiome profiles that influence tenofovir distribution in the female genital tract by Alyssa M. Lantz, Christopher Staley, Melanie R. Nicol

“…OBJECTIVES/GOALS: An ex-vivo tissue model has been developed to predict target concentrations of tenofovir diphosphate (TFVdp; active metabolite of tenofovir) but has not been utilized to see how vaginal dysbiosis affects TFVdp/dATP exposure in female genital tract (FGT). …”
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Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. by Jocelyn T Kim, Emery Chang, Alex Sigal, David Baltimore

“…Here, we investigated the efficiency of DC-to-T cell transmission on the number of cells infected and the sensitivity of this type of transmission to the antiretroviral drugs tenofovir (TFV) and raltegravir (RAL). We observed activated monocyte-derived and myeloid DCs amplified T cell infection, which resulted in drug insensitivity. …”
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Bictegravir/Emtricitabine/Tenofovir Alafenamide for HIV-1: What is the Hidden Potential of This Emerging Treatment? by Januszka JE, Drwiega EN, Badowski ME

“…Wood St., Rm 164, M/C 886, Chicago, IL, 60612, USA, Email badowski@uic.eduAbstract: Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is a single-tablet antiretroviral therapy regimen. …”
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Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis by Manjula Gunawardana, Mariana Remedios-Chan, Debbie Sanchez, Simon Webster, Patricia Galvan, Rob Fanter, Amalia E. Castonguay, Paul Webster, John A. Moss, Joseph Kuo, Philippe A. Gallay, Kathleen L. Vincent, Massoud Motamedi, Dana Weinberger, Mark A. Marzinke, Mark A. Marzinke, Craig W. Hendrix, Marc M. Baum

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Cost-effectiveness of tenofovir in the treatment of patients with chronic hepatitis B: data from literature by Massimo Fasano, Giorgio L. Colombo, Sergio Di Matteo, Claudia Randazzo, Gioacchino Angarano, Teresa Antonia Santantonio

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Safety and Efficacy of Fixed Drug Combination Tenofovir, Lamivudine and Efavirenz to Prevent Transmission of HIV by Pramendra Sirohi, Anubhav Dabas, Hardeva Ram Nehara, Atma Ram Chhimpa, Mahesh Kumar Barodia, Rakesh Kumar

“…The first-line regimen for prophylaxis in HIV infected pregnant women is combination of Tenofovir, Lamivudine and Efavirenz (TLE). Aim: To evaluate the safety and efficacy of the TLE regimen in the Prevention of Mother-To-Child Transmission (PMTCT) of HIV. …”
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Selective Lewis Acid Catalyzed Assembly of Phosphonomethyl Ethers: Three-Step Synthesis of Tenofovir by Ocampo, Charles Edward, Lee, Doris, Jamison, Timothy F

“…The utility of this method is demonstrated in a novel synthesis of tenofovir, an antiretroviral drug used in the treatment of HIV/AIDS and hepatitis B.…”
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Biphasic Elimination of Tenofovir Diphosphate and Nonlinear Pharmacokinetics of Zidovudine Triphosphate in a Microdosing Study by Chen, Jianmeng, Flexner, Charles, Liberman, Rosa G., Skipper, Paul L., Louissaint, Nicolette A., Hendrix, Craig W., Fuchs, Edward J., Tannenbaum, Steven Robert

“…To evaluate the prediction of microdosing for active intracellular drug metabolites, we compared the PK profile of 2 antiretroviral drugs, zidovudine (ZDV) and tenofovir (TFV), in microdose and standard dosing regimens. …”
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Is the risk of tenofovir-induced nephrotoxicity similar in treatment-naïve compared to treatment-experienced patients? by Low, Joo Zheng, Khoo, Su Pei, Nor Azmi, Nuruljannah, Chong, Meng Li, Sulaiman, Helmi, Azwa, Iskandar, Tan, Ching Hooi, Kamarulzaman, Adeeba, Rajasuriar, Reena

“…Background: Tenofovir disoproxil fumarate (TDF) is the recommended first-line nucleoside reverse transcriptase inhibitor (NRTI) in the management of human immunodeficiency virus (HIV); however, its use is associated with nephrotoxicity. …”

Renal function and lipid metabolism in Japanese HIV-1-positive individuals 288 weeks after switching from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate: a single-center, retrospective cohort study by Kensuke Abe, Junji Imamura, Akiko Sasaki, Tomoko Suzuki, Satomi Kamio, Taku Obara, Toshihiro Ito

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Incidence and association of renal dysfunction with a long term Tenofovir-based therapy among HIV-positive naïve cohort at Ronald Ross Hospital by Enock Wantakisha, Derick Munkonbwe, Tshula Tumba, Charles Michelo

Subjects: “…tenofovir…”
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Pharmacokinetic Feasibility of Stability-Enhanced Solid-State (SESS) Tenofovir Disoproxil Free Base Crystal by Byoung Hoon You, Mingoo Bae, Seung Yon Han, Jieun Jung, Kiwon Jung, Young Hee Choi

Subjects: “…tenofovir (TEV)…”
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Observation of Glomerular Filtration Change in Chronic Hepatitis B Patients Using Tenofovir Disoproxil Fumarate by Meltem Karslıoğlu

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Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma by Sung Won Lee, Jonggi Choi, Seung Up Kim, Young-Suk Lim

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Efficacy and Safety of Tenofovir Disoproxil Fumarate in Asian-Americans with Chronic Hepatitis B in Community Setting

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Switching from entecavir to tenofovir alafenamide for maintaining complete virological response in chronic hepatitis B by Shun Ishido, Nobuharu Tamaki, Naoki Uchihara, Keito Suzuki, Yuki Tanaka, Haruka Miyamoto, Michiko Yamada, Hiroaki Matsumoto, Tsubasa Nobusawa, Taisei Keitoku, Kenta Takaura, Shohei Tanaka, Chiaki Maeyashiki, Yutaka Yasui, Yuka Takahashi, Kaoru Tsuchiya, Hiroyuki Nakanishi, Jun Itakura, Masayuki Kurosaki, Namiki Izumi

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Triple-combination rilpivirine, emtricitabine, and tenofovir (Complera™/Eviplera™) in the treatment of HIV infection by Bernardini C, Maggiolo F

“…Claudia Bernardini, Franco MaggioloDivision of Infectious Diseases and Unit of Antiviral Therapy, AO Papa Giovanni XXIII, Bergamo, ItalyAbstract: The combination rilpivirine (RPV)/emtricitabine (FTC)/tenofovir (TDF) is a once-daily, single-tablet regimen (STR) containing one nonnucleoside reverse-transcriptase inhibitor associated with two nucleos(t)ide reverse transcriptase inhibitors. …”
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Virologic response and safety of tenofovir versus entecavir in treatment-naïve chronic Hepatitis B patients by Hyung Min Yu, So Young Kwon, Jiwan Kim, Hyun Ah Chung, Se Woong Kwon, Taek Gun Jeong, Sang Hee An, Gyung Won Jeong, Seon Ung Yun, Jae Ki Min, Jeong Han Kim, Won Hyeok Choe

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Comparing pharmacologic measures of tenofovir exposure in a U.S. pre-exposure prophylaxis randomized trial. by Sanjiv M Baxi, Eric Vittinghoff, Peter Bacchetti, Yong Huang, Kata Chillag, Ryan Wiegand, Peter L Anderson, Robert Grant, Ruth M Greenblatt, Susan Buchbinder, Monica Gandhi, Albert Y Liu

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