Effect of tenofovir on nucleotidases and cytokines in HIV-1 target cells. by Nabanita Biswas, Marta Rodriguez-Garcia, Sarah G Crist, Zheng Shen, Jack E Bodwell, John V Fahey, Charles R Wira

“…Tenofovir (TFV) has been widely used for pre-exposure prophylaxis of HIV-1 infection with mixed results. …”
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Model Linking Plasma and Intracellular Tenofovir/Emtricitabine with Deoxynucleoside Triphosphates. by Xinhui Chen, Sharon M Seifert, Jose R Castillo-Mancilla, Lane R Bushman, Jia-Hua Zheng, Jennifer J Kiser, Samantha MaWhinney, Peter L Anderson

“…The coformulation of the nucleos(t)ide analogs (NA) tenofovir (TFV) disoproxil fumarate (TDF) and emtricitabine (FTC) is approved for HIV-infection treatment and prevention. …”
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Tenofovir alafenamide nephrotoxicity: a case report and literature review by Thornthun Ueaphongsukkit, Sivaporn Gatechompol, Anchalee Avihingsanon, Jerasit Surintrspanont, Kroonpong Iampenkhae, Yingyos Avihingsanon, Suwasin Udomkarnjananun

Subjects: “…Tenofovir alafenamide…”
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Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel. by Yajing Gao, David F Katz

“…Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting results. …”
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Drug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxis. by Thanyanan Chaowanachan, Emily Krogstad, Cameron Ball, Kim A Woodrow

“…Here we show unique combination drug activities mediated by our polymeric delivery systems when combined with free tenofovir (TFV).Biodegradable poly(lactide-co-glycolide) nanoparticles loaded with efavirenz (NP-EFV) or saquinavir (NP-SQV) were individually prepared by emulsion or nanoprecipitation techniques. …”
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Effects of Genetic Polymorphisms of Cathepsin A on Metabolism of Tenofovir Alafenamide by Soichiro Ito, Takeshi Hirota, Miyu Yanai, Mai Muto, Eri Watanabe, Yuki Taya, Ichiro Ieiri

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Effects of Hydrochlorothiazide on Tenofovir Disoproxil Fumarate-Induced Nephrotoxicity in Rats by Iman G.Al-Rakhat, Nada N.Al-Shawi

Subjects: “…nephrotoxicity, tenofovir, hydrochlorothiazide, cystatin c, il-10…”
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Tenofovir-associated kidney disease in Africans: a systematic review by Takudzwa J. Mtisi, Chiratidzo E. Ndhlovu, Chiedza C. Maponga, Gene D. Morse

Subjects: “…Tenofovir…”
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Tenofovir disoproxil fumarate for the treatment of chronic hepatitis B infection by J Jones, J Colquitt, J Shepherd, P Harris, K Cooper

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Corrigendum: The role of drug transporters in the kidney: lessons from tenofovir by Darren eMoss

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Di- tert -butyl Phosphonate Route to the Antiviral Drug Tenofovir by Dietz, Jule-Philipp, Ferenc, Dorota, Jamison, Timothy F, Gupton, B Frank, Opatz, Till

“…For the synthesis of tenofovir, a two-step sequence was developed using Mg(OtBu)2 as the base for the alkylation of (R)-9-(2-hydroxypropyl)adenine. …”
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Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B by Juan Li, Chunhua Hu, Yi Chen, Rou Zhang, Shan Fu, Mimi Zhou, Zhijie Gao, Mengjun Fu, Taotao Yan, Yuan Yang, Jianzhou Li, Jinfeng Liu, Tianyan Chen, Yingren Zhao, Yingli He

Subjects: “…Tenofovir alafenamide…”
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Observational study on the response of tenofovir monotherapy versus tenofovir plus telbivudine dual therapy in patients with hepatitis B virus related acute on chronic liver failure by Abul H Manik, Debraj Malakar, Sheikh M Noor-E-Alam, Mamun A Mahtab, Dulal C Das, Ayub A Mamun, Sakirul Khan, Mohammad Fazle Akbar, Zakiur Rahman, Salimur Rahman

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Treatment persistence of bictegravir/emtricitabine/tenofovir alafenamide and efavirenz + lamivudine + tenofovir disoproxil among HIV-1 patients newly starting treatment in Hunan Province in China by Cao Jing, Tang Wei, Wang Ning, Zheng Fang, Xiao Gang, Wang Xingzhi, Zhou Guoqiang, Wang Min

“…Abstract Background Though bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF) have been regulatory approved and included in the National Reimbursement Drug List in China, due to the affordability concern, generic version of efavirenz + lamivudine + tenofovir (EFV + 3TC + TDF) is still recommended as the first-line therapy in the clinical guideline and widely used in clinical practice. …”
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Renal and bone side effects of long-term use of entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide fumarate in patients with Hepatitis B: a network meta-analysis by Zekun Liu, Zhenzhen Zhao, Xuefeng Ma, Shousheng Liu, Yongning Xin

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P1- HIGH VIRAL SUPPRESSION AND IMPROVED SAFETY PROFILE OF TENOFOVIR ALAFENAMIDE RELATIVE TO TENOFOVIR DISOPROXIL FUMARATE IN CHRONIC HEPATITIS B PATIENTS TREATED FOR 5 YEARS by Wai Kay Seto, Ting-Tsung Chang, Abhijit Chowdhry, Chi-Yi Chen, Mustafa Kemal Celen, Xiaoli Ma, Mang Ma, Ajay Duseja, Ki Tae Yoon, Wan Cheng Chow, Leland Yee, Gregor Weber, Ms Jin Youn, John F. Flaherty, Anuj Gaggar, Bing Gao, Gregory Camus, Eric Bassetti, Jae Seok Hwang, Tetshuro Inokuma, Young- Suk Lin, Edward J. Gane

“…Introduction and Objectives: Tenofovir Alafenamide (TAF) is a preferred treatment in the most recent EASL and AASLD HBV Guidelines, especially in patients with risk factors for TDF-associated renal and bone effects. …”
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Evaluation of genotoxic activity of tenofovir disoproxil fumarate in human peripheral lymphocytes by Kubra Kurt, Lale Donbak, Ahmet Kayraldiz

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Tenofovir Alafenamide Rescues Renal Tubules in Patients with Chronic Hepatitis B by Tomoya Sano, Takumi Kawaguchi, Tatsuya Ide, Keisuke Amano, Reiichiro Kuwahara, Teruko Arinaga-Hino, Takuji Torimura

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Tenofovir induced acute kidney injury and its outcome; an Indian perspective by Sreedhara C. Gurusiddaiah, Bhushan C Shetty, Kishan Aralapuram, Shashank Shetty, Mythri Shankar, Mahesha Vankalakunti

Subjects: “…tenofovir…”
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Tenofovir-associated nephrotoxicity in patients with chronic hepatitis B: two cases by Hyeki Cho, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Kook-Hwan Oh, Kyoungbun Lee, Syifa Mustika, Jung-Hwan Yoon, Yoon Jun Kim

Subjects: “…Tenofovir…”
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