Analogs in the treatment of chronic hepatitis B: real life experience with tenofovir and entecavir by Rosanna Villani, Roberta Forlano, Gianluigi Vendemiale, Gaetano Serviddio

Subjects: “…Tenofovir…”
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Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture. by Zheng Shen, John V Fahey, Jack E Bodwell, Marta Rodriguez-Garcia, Angela D M Kashuba, Charles R Wira

“…The conflicting results of recent pre-exposure prophylaxis (PrEP) trials utilizing tenofovir (TFV) to prevent HIV infection in women led us to evaluate the accumulation of intracellular TFV-diphosphate (TFV-DP) in cells from the female reproductive tract (FRT) and whether sex hormones influence the presence of TFV-DP in these cells. …”
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Bone outcomes in virally suppressed youth with HIV switching to tenofovir disoproxil fumarate by Kate Braithwaite, Tristan D. McPherson, Yanhan Shen, Stephen Arpadi, Stephanie Shiau, Gillian Sorour, Karl-Günter Technau, Michael T. Yin

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The partial virological response to Tenofovir monotherapy in naïve patients with chronic hepatitis B by Habip Gedik, Muge Sonmezisik

“…Keywords: Chronic hepatitis B, Tenofovir, partial response, Entecavir, combination therapy …”
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The Role of Tenofovir on the Prevention of Hepatitis B Transmission in Mothers with High Viral Load by Jung Hyun Kwon

“…Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load…”
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Bone turnover markers in HIV-infected women on tenofovir-based antiretroviral therapy by Mwila Mulubwa, Michelle Viljoen, Iolanthe M. Kruger, Herculina S. Kruger, Malie Rheeders

Subjects: “…Tenofovir levels…”
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The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses by Gibbs Julie E, Anthonypillai Christy, Thomas Sarah A

“…<p>Abstract</p> <p>Background</p> <p>Tenofovir disoproxil fumarate, a prodrug of the nucleotide reverse transcriptase inhibitor, tenofovir (9-[9(R)-2-(phosphonomethoxy)propyl]adenine; PMPA), was recently approved for use in the combination therapy of human immunodeficiency virus (HIV)-1 infection. …”
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Rates and predictors of switching to tenofovir alafenamide-containing ART in a nationwide cohort by Bernard Surial, Matthias Cavassini, Alexandra Calmy, Jan Fehr, Marcel Stöckle, Enos Bernasconi, Bianca Roth, Christoph A. Fux, Helen Kovari, Hansjakob Furrer, Andri Rauch, Gilles Wandeler, the Swiss HIV Cohort Study

Subjects: “…Tenofovir alafenamide…”
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Tenofovir-induced Fanconi syndrome in a patient with chronic hepatitis B monoinfection by Fabio Conti, Giovanni Vitale, Carmela Cursaro, Mauro Bernardi, Pietro Andreone

“…Tenofovir disoproxil fumarate (TDF) is a nucleotide reverse transcriptase inhibitor indicated for treatment of patients with chronic hepatitis B virus (CHB) and human immunodeficiency virus (HIV) infections. …”
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Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa by Y. Singh, J. Castillo-Mancilla, R. Madimabe, L. Jennings, C. M. Ferraris, R. N. Robbins, P. L. Anderson, R. H. Remien, C. Orrell

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Discovery of Genetic Variants of the Kinases That Activate Tenofovir in a Compartment-specific Manner by Julie M. Lade, Elaine E. To, Craig W. Hendrix, Namandjé N. Bumpus

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Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles by Denise A. Cobb, Nathan Smith, Suyash Deodhar, Aditya N. Bade, Nagsen Gautam, Bhagya Laxmi Dyavar Shetty, JoEllyn McMillan, Yazen Alnouti, Samuel M. Cohen, Howard E. Gendelman, Benson Edagwa

“…Here, the authors report two lipophilic tenofovir (TVF) ProTide nanoformulations, NM1TFV and NM2TFV, which sustain drug levels above therapeutic concentrations for two months after a single intramuscular dose in rats.…”
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Tenofovir-associated renal toxicity in a cohort of HIV infected patients in Ghana by Edmund T. Nartey, Raymond A. Tetteh, Barbara A. Yankey, Aukje K. Mantel-Teeuwisse, Hubert G. M. Leufkens, Alexander N. O. Dodoo, Margaret Lartey

Subjects: “…Tenofovir disoproxil fumarate…”
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Development and validation of analytical method for quantitation of Emtricitabine, Tenofovir, Efavirenz based on HPLC by Arun Ramaswamy, Anton Smith Arul Gnana Dhas

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Review: Efficacy and safety of tenofovir disoproxil fumarate in patients with chronic hepatitis B by Andrés Duarte-Rojo, E. Jenny Heathcote

“…Treatment for this condition may need to be lifelong, thus the drugs used must be both efficacious and safe. Clinical trials of tenofovir have demonstrated a good safety profile for this drug and it has potent antiviral properties. …”
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Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel by Archary, D, Seaton, K E, Passmore, J S, Werner, L, Deal, A, Yates, N L, Bergin, P, Liebenberg, L J, Samsunder, N, Mureithi, M W, Altfeld, M, Garrett, N, Abdool Karim, Q, Abdool Karim, S S, Morris, L, Tomaras, G D, Dunphy, Laura J., Arnold, Kelly Benedict, Lauffenburger, Douglas A

“…Linear mixed effect modeling and partial least squares discriminant analysis was used to identify multivariate antibody signatures associated with tenofovir use. There were significantly higher response rates to gp120 Env (P=0.03), p24 (P=0.002), and p66 (P=0.009) in plasma and GT in women assigned to tenofovir than placebo gel at multiple time points post infection. …”
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Pharmacokinetics of oral tenofovir disoproxil fumarate in pregnancy and lactation: A systematic review by Bierhoff, M, Smolders, EJ, Tanning, J, Burger, DM, Spijker, R, Rijken, MJ, Angkurawaranon, C, McGready, R, White, NJ, Nosten, F, van Vugt, M

“…<p><strong>Background:</strong><br /> Tenofovir disoproxil fumarate (TDF), the oral prodrug of tenofovir (TFV), is advocated in pregnancy for prevention of mother-to-child transmission (PMCT) with failure of hepatitis B immunoglobulin and vaccination. …”

Cost–utility analysis of tenofovir disoproxil fumarate in the treatment of chronic hepatitis B by Dakin, H, Bentley, A, Dusheiko, G

“…<p><strong>Objective</strong></p> <p>The aim of this study was to assess the cost-effectiveness of tenofovir disoproxil fumarate (TDF) in the treatment of chronic hepatitis B (CHB) versus alternative nucleos(t)ides from a UK National Health Service (NHS) perspective.…”

Grado de satisfacción y conocimiento de pacientes positivos para HIV ante el cambio de tenofovir a tenofovir-alafenamida en tratamientos con emtricitabina y rilpivirina by Manuel Vélez-Díaz-Pallarés, Teresa Gramage-Caro, Miguel Ángel Rodríguez-Sagrado, Beatriz Montero-Llorente, Teresa Bermejo-Vicedo

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Cost-effectiveness of the once-daily efavirenz/emtricitabine/tenofovir tablet compared with the once-daily elvitegravir/cobicistat/emtricitabine/tenofovir tablet as first-line antiretroviral therapy in HIV-infected adults in the US by Juday T, Correll T, Anene A, Broder MS, Ortendahl J, Bentley T

“…Timothy Juday,1 Todd Correll,1 Ayanna Anene,2 Michael S Broder,2 Jesse Ortendahl,2 Tanya Bentley21Bristol-Myers Squibb, Plainsboro, NJ, USA; 2Partnership for Health Analytic Research LLC, Beverly Hills, CA, USABackground: February 2013 US treatment guidelines recommend the once-daily tablet of efavirenz/emtricitabine/tenofovir (Atripla&reg;) as a preferred regimen and the once-daily tablet of elvitegravir/cobicistat/emtricitabine/tenofovir (Stribild&trade;) as an alternative regimen for first-line treatment of human immunodeficiency virus (HIV). …”
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