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290241
Trehalose Attenuates Oxidative Stress and Endoplasmic Reticulum Stress-Mediated Apoptosis in IPEC-J2 Cells Subjected to Heat Stress
Published 2022-08-01“…This study was carried out to investigate the effects of trehalose (Tre) on antioxidant capacity, endoplasmic reticulum stress (ERS) response and apoptosis of heat-stressed intestinal porcine epithelial cells (IPEC-J2). …”
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290242
Real-world effectiveness of voxilaprevir/velpatasvir/sofosbuvir in patients following DAA failure
Published 2024-03-01“…Most patients were infected with HCV genotype 1 (56%) and 3 (32%). 86% of patients carried resistance-associated substitutions in the NS3, NS5A or NS5B regions. …”
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290243
A modified LC-MS/MS method for the detection of whole blood tacrolimus and its clinical value in Chinese kidney transplant patients
Published 2022-08-01“…In this way, the instrument throughput is also improved and realizing the detection of 2 samples within 3.5 min and carried out a shorter analyzing time for each sample of 1.75 min. …”
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290244
A TNFR2-Specific TNF Fusion Protein With Improved In Vivo Activity
Published 2022-06-01“…With the aim to improve the in vivo availability of TNFR2-specific TNF fusion proteins, we used here the neonatal Fc receptor (FcRn)-interacting IgG1 molecule as an oligomerizing building block and generated a new TNFR2 agonist with improved serum retention and superior in vivo activity.MethodsSingle-chain encoded murine TNF80 trimers (sc(mu)TNF80) were fused to the C-terminus of an in mice irrelevant IgG1 molecule carrying the N297A mutation which avoids/minimizes interaction with Fcγ-receptors (FcγRs). …”
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290245
Estado nutricional y marcadores de estrés oxidativo en trabajadores agrícolas, Arroyo Naranjo, 2019 / Nutritional status and oxidative stress markers in agricultural workers from t...
Published 2022-09-01“…Methods: A descriptive and cross-sectional study was carried out with a sample of 68 workers obtained by random sampling and classified, according to body mass index, in three groups: normal weight, overweight and obese. …”
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290246
Consenso sobre el diagnóstico y el tratamiento de la alergia a las proteínas de la leche de vaca de la Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición
Published 2022-04-01“…A search of the medical literature was carried out to support the information presented in each module and 28 statements were then selected. …”
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290247
Shedding Light on the Role of Na,K-ATPase as a Phosphatase during Matrix-Vesicle-Mediated Mineralization
Published 2022-12-01“…It was hypothesized that the loss of Na/K asymmetry in MVs could be caused by a complete depletion of ATP inside MVs, impairing the maintenance of symmetry by NKA. Our study carried out on NKA-liposomes confirmed that NKA could contribute to mineral formation inside MVs, which might complement the known action of PHOSPHO1 in the MV lumen.…”
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290248
Prescripción de ejercicio en pacientes con cirrosis: recomendaciones para la atención clínica
Published 2019-07-01“…Even though some studies have reported an acute, exercise-induced increase in the hepatic venous pressure gradient (HVPG), the opposite (a decrease in the HVPG) has been shown by recent data after an exercise program carried out for >14 weeks. In addition to that benefit, improvement has been described in the metabolic profile, quality of life, muscle mass, cardiopulmonary function, and nutritional status. …”
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290249
Feasibility, acceptability and practicality of transcranial stimulation in obsessive compulsive symptoms (FEATSOCS): A randomised controlled crossover trial
Published 2023-04-01“…Each course comprised four 20-min 2 mA stimulations, delivered over two consecutive days, separated by a ‘washout’ period of at least four weeks. Assessments were carried out by raters who were blind to stimulation-type. …”
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290250
Terahertz Rotational Spectroscopy of Greenhouse Gases Using Long Interaction Path-Lengths
Published 2021-01-01“…To illustrate, new measurements on CH<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>4</mn></msub></semantics></math></inline-formula> and CF<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>4</mn></msub></semantics></math></inline-formula> have been carried out. For CH<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>4</mn></msub></semantics></math></inline-formula>, pure rotational transitions, recorded by cw-THz photomixing up to 2.6 THz in a White type cell adjusted to 20 m, have allowed to update the methane line list of atmospheric databases. …”
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290251
Spatial modeling, risk mapping, change detection, and outbreak trend analysis of coronavirus (COVID-19) in Iran (days between February 19 and June 14, 2020)
Published 2020-09-01“…Methods: This is the first comprehensive study of COVID-19 in Iran; and it carries out spatial modeling, risk mapping, change detection, and outbreak trend analysis of the disease spread. …”
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290252
Digging into the NGS Information from a Large-Scale South European Population with Metastatic/Unresectable Pancreatic Ductal Adenocarcinoma: A Real-World Genomic Depiction
Published 2023-12-01“…<i>BRCA1/2</i> variants with on-label indications were detected in 2%, and 87.50% carried a variant associated with off-label treatment (<i>KRAS</i>, <i>ERBB2</i>, <i>STK11</i>, or HRR-genes), while 3.5% of the alterations had unknown/preliminary-studied actionability (<i>TP53/CDKN2A</i>). …”
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290253
Chemical Composition and Biological Properties of Two <i>Jatropha</i> Species: Different Parts and Different Extraction Methods
Published 2021-05-01“…Finally, a bioinformatics analysis was carried out with the aim to unravel the putative mechanisms consistent with both metabolomic fingerprints and pharmacological effects. …”
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290254
The Responses of Leaf Litter Calcium, Magnesium, and Manganese Dynamics to Simulated Nitrogen Deposition and Reduced Precipitation Vary with Different Decomposition Stages
Published 2021-10-01“…Thus, to better understand Ca, Mg, and Mn dynamics during leaf litter decomposition in the scenario of increasing N deposition and decreasing precipitation, we carried out a two-year field litterbag experiment in a natural evergreen broad-leaved forest in the central area of the rainy area of Western China. …”
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290255
The Asociación Mexicana de Gastroenterología consensus on the diagnosis and treatment of acute pancreatitis in children and adolescents
Published 2023-07-01“…Despite the ever-increasing evidence regarding the management of AP in children and adults, therapeutic actions that could potentially affect having a poor prognosis in those patients, especially in the pediatric population, continue to be carried out. Therefore, the Asociación Mexicana de Gastroenterología convened a group of 24 expert pediatric gastroenterologists from different institutions and areas of Mexico, as well as 2 pediatric nutritionists and 2 specialists in pediatric surgery, to discuss different aspects of the epidemiology, diagnosis, and treatment of AP and RAP in the pediatric population. …”
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290256
Tibetan medicine Jiuwei Qingpeng San could inhibit influenza A virus induced lung injury via regulating the expression of IFN-γ and its signaling pathway
Published 2023-09-01“…A replication competent PR8 carrying Gaussia luciferase (PR8-Luci) was further utilized to infect BEAS-2B cells to determine the inhibitory activity of virus replication by detection of the intensity of bioluminescence that correlates with viral load. …”
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290257
Use of Radiology, D-Dimer, and Mean Platelet Volume Combination as a Prognostic Marker in Hospitalized Coronavirus Disease-19 Patients
Published 2022-02-01“…Receiver operator curve (ROC) analyzes were carried out to assess the efficacy of D-dimer and MPV parameters as prognostic markers.ResultsBetween the mentioned dates, 575 of 1,564 patients were found to be compatible with COVID-19, and the number of patients who were included in the study was 306. …”
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290258
Preliminary Assessment and Verification of the Langley Plots Calibration of the Sun Photometer at Mt Foyeding Observatory, Beijing
Published 2022-09-01“…We explored whether the Langley plot calibration is practicable for this mountainous site by analyzing the aerosol climatology and carrying out a case study. Then, the aerosol optical depth (AOD) results were verified under the reference of AERONET AOD. …”
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290259
Association of High‐Sensitivity Troponin T and I Blood Concentrations With All‐Cause Mortality and Cardiovascular Outcome in Stable Patients—Results From the INTERCATH Cohort
Published 2022-09-01“…To investigate the association of hsTnT and hsTnI with outcome, a multivariable analysis adjusting for classical cardiovascular risk factors, low‐density lipoprotein cholesterol, estimated glomerular filtration rate, hs‐CRP (high‐sensitivity C‐reactive protein), NT‐proBNP (N‐terminal pro–brain natriuretic peptide), and Gensini score was carried out. Of 1829 patients, 27.9% were women, and the mean age was 68.6±10.9 years. …”
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290260
Robotic Versus Laparoscopic Gastrectomy for Gastric Cancer: A Mega Meta-Analysis
Published 2022-06-01“…To systematically assess the safety and effectiveness of robotic gastrectomy for gastric cancer, we carried out a systematic review and meta-analysis on short-term and long-term outcomes of robotic gastrectomy.MethodsIn order to find relevant studies on the efficacy and safety of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) in the treatment of gastric cancer, numerous medical databases including PubMed, Medline, Cochrane Library, Embase, Google Scholar, and China Journal Full-text Database (CNKI) were consulted, and Chinese and English studies on the efficacy and safety of RG and LG in the treatment of gastric cancer published from 2012 to 2022 were screened according to inclusion and exclusion criteria, and a meta-analysis was conducted using RevMan 5.4 software.ResultsThe meta-analysis inlcuded 48 literatures, with 20,151 gastric cancer patients, including 6,175 in the RG group and 13,976 in the LG group, respectively. …”
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