Wuhu decoction combined with azithromycin for treatment of Mycoplasma pneumoniae pneumonia in Asian children: a systematic review and meta analysis of randomized controlled trials by Shuo Yang, Shuo Yang, Xinying Liu, Xinying Liu, Huizhe Wang, Huizhe Wang, Haokai Wang, Haokai Wang, Dan Sun, Dan Sun, Yaowei Han, Yaowei Han, Huanmin Li, Huanmin Li, Xinmin Li, Xinmin Li

“…Additionally, meta-regression analysis and subgroup analysis were carried out on primary outcomes to identify potential sources of heterogeneity and confounding factors.Results: A total of 22 randomized controlled trials involving 2,026 patients were included in this study. …”
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Relationship between the structure, function and endothelial damage, and vascular ageing and the biopsychological situation in adults diagnosed with persistent COVID (BioICOPER stu... by Leticia Gómez-Sánchez, Leticia Gómez-Sánchez, Olaya Tamayo-Morales, Olaya Tamayo-Morales, Olaya Tamayo-Morales, Nuria Suárez-Moreno, Nuria Suárez-Moreno, Nuria Suárez-Moreno, Jesus F. Bermejo-Martín, Jesus F. Bermejo-Martín, Andrea Domínguez-Martín, Andrea Domínguez-Martín, Andrea Domínguez-Martín, José A. Martín-Oterino, José A. Martín-Oterino, José A. Martín-Oterino, José A. Martín-Oterino, José I. Martín-González, José I. Martín-González, José I. Martín-González, José I. Martín-González, David González-Calle, David González-Calle, David González-Calle, David González-Calle, Ángel García-García, Ángel García-García, Ángel García-García, Ángel García-García, Cristina Lugones-Sánchez, Cristina Lugones-Sánchez, Cristina Lugones-Sánchez, Susana González-Sánchez, Susana González-Sánchez, Susana González-Sánchez, Raquel Jiménez-Gómez, Raquel Jiménez-Gómez, Raquel Jiménez-Gómez, Luis García-Ortiz, Luis García-Ortiz, Luis García-Ortiz, Luis García-Ortiz, Luis García-Ortiz, Manuel A. Gómez-Marcos, Manuel A. Gómez-Marcos, Manuel A. Gómez-Marcos, Manuel A. Gómez-Marcos, Manuel A. Gómez-Marcos, Elena Navarro-Matías, Elena Navarro-Matías, Elena Navarro-Matías, ICOPER investigators group

“…The objective of this study is to analyse how the structure, vascular function, vascular ageing and endothelial damage are related to the biopsychological situation in adults diagnosed with persistent COVID and the differences by gender.Methods: This cross-sectional, descriptive, observational study will be carried out in the Primary Care Research Unit of Salamanca (APISAL) and in the BioSepsis laboratory of the University of Salamanca. …”
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Cardiovascular abnormalities and its correlation with genotypes of children with osteogenesis imperfecta by Dichen Zhao, Yongtai Liu, Jidong Liu, Jing Hu, Qian Zhang, Ou Wang, Yan Jiang, Weibo Xia, Xiaoping Xing, Mei Li

“…Abnormalities of echocardiography were found in 6 OI children, including enlarged left atrium (n=5), increased internal diameter of the left ventricle (n=1), who all carried the COL1A1 mutation. Mild regurgitation of mitral or tricuspid valves was observed in 26 OI patients. …”
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Quantifying Left Atrial Size in the Context of Atrial Fibrillation Ablation: Which Echocardiographic Method Correlates to Outcome of Pulmonary Venous Isolation? by Patrick Leitz, Lena Marie Stebel, Christian Andresen, Christian Ellermann, Fatih Güner, Florian Reinke, Simon Kochhäuser, Gerrit Frommeyer, Julia Köbe, Kristina Wasmer, Philipp S. Lange, Stefan Orwat, Lars Eckardt, Dirk G. Dechering

“…Measurements of the LA were carried out by a single observer in transthoracic echocardiograms (TTE) performed prior to ablation. …”
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Medical Care for Tuberculosis-HIV-Coinfected Patients in Russia with Respect to a Changeable Patients’ Structure by Olga P. Frolova, Olga V. Butylchenko, Patimat G. Gadzhieva, Margarita Yu. Timofeeva, Valeria A. Basangova, Vladislava O. Petrova, Inna A. Fadeeva, Maria I. Kashutina, Nadezhda N. Zabroda, Artem A. Basov, Elena V. Belova, Yury V. Zhernov, Oleg V. Mitrokhin, Inga I. Enilenis, Lyudmila P. Severova

“…Based on the results obtained, our goal was to point out the parameters that need to be taken into account when developing approaches to improve the organization of TB control care for people with HIV infection. We have carried out a cross-sectional, retrospective, epidemiological study using government TB registry data from four regions in two federal districts of Russia in 2019. …”
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A survey on clinical communication competence of psychiatric nurses in Guangdong Province (广东省精神科护士临床沟通能力调查分析) by LI Xiaochan (李晓婵), ZHUANG Jingyi (庄静仪), ZHANG Huixian (张慧娴), XIE Jiao (谢姣), HAO Li (郝丽), LUO Juanjuan (罗娟娟), ZENG Junfang (曾君芳), ZOU Caimei (邹彩媚)

“…Targeted training program should be carried out to improve the clinical communication competence of psychiatric nurses in Guangdong Province (目的 调查广东省精神科护士的临床沟通能力水平并分析其影响因素, 为管理层提高精神科护士沟通能力提供参考依据。…”
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The spleen-strengthening and liver-draining herbal formula treatment of non-alcoholic fatty liver disease by regulation of intestinal flora in clinical trial by Dengcheng Hui, Dengcheng Hui, Dengcheng Hui, Lu Liu, Lu Liu, Lu Liu, Nisma Lena Bahaji Azami, Nisma Lena Bahaji Azami, Nisma Lena Bahaji Azami, Jingru Song, Yanping Huang, Wan Xu, Chao Wu, Chao Wu, Chao Wu, Dong Xie, Yulang Jiang, Yulang Jiang, Yulang Jiang, Yanqin Bian, Mingyu Sun, Mingyu Sun, Mingyu Sun

“…At the genus level, Coprococcus (Lachnospiraceae family), Lachnospiraceae_NK4A136 group (Lachnospiraceae family), and Ruminococcus (Ruminococcaceae family) were significantly higher in the SLF group after treatment, and there was also a tendency for Bilophila (Desulfovibrionaceae family) to be back-regulated toward HC.ConclusionsSLF can improve liver function and glucolipid metabolism in patients with NAFLD and lower down liver fat content to some extent. SLF could be carried out by regulating the disturbance of intestinal flora, especially Coprococcus, Lachnospiraceae_NK4A136 group, and Ruminococcus genus.…”
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Diagnostic Potential of Exosomal HypoxamiRs in the Context of Hypoxia–Sumoylation–HypoxamiRs in Early Onset Preeclampsia at the Preclinical Stage by Vladislava Gusar, Angelika Timofeeva, Vitaliy Chagovets, Nataliya Kan, Mikhail Vysokikh, Maria Marey, Anna Karapetyan, Oleg Baev, Gennadiy Sukhikh

“…Specific exomotifs of studied miRNAs were also identified, to which the sumoylated ribonucleoprotein hnRNPA2/B1 binds, carrying out their packaging into exosomes. The expression of conjugated SUMO 1 (<i>p</i> = 0.05), SUMO 2/3/4 (<i>p</i> = 0.03), and UBC9 (<i>p</i> = 0.1) was increased in exosomes at early-onset PE, and the expression of free SUMO 1 (<i>p</i> = 0.03) and SUMO 2/3/4 (<i>p</i> = 0.01) was significantly increased in the placenta, as an adaptive response to hypoxia. …”
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ORGANIZING EARLY DIAGNOSIS AND SCREENING PROGRAMS FOR BREAST CANCER IN TURKEY by Vahit Özmen, Caner Fidaner, Erol Aksaz, Ümit Bayol, İsmet Dede, Erdem Göker, Bahadır M. Güllüoğlu, Abdurrahman Işıkdoğan, Uğur Topal, Mehmet Uhri, Zafer Utkan, Nurullah Zengin, Murat Tuncer

“…A realistic budget for screening projects should be prepared and carried out. There should be a high-level coordination and a comprehensive organization among study groups, screening centers, and institutions. …”
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Peripheral blood cellular profile at pre-lymphodepletion is associated with CD19-targeted CAR-T cell-associated neurotoxicity by Serena De Matteis, Michele Dicataldo, Michele Dicataldo, Beatrice Casadei, Beatrice Casadei, Gianluca Storci, Noemi Laprovitera, Mario Arpinati, Enrico Maffini, Pietro Cortelli, Pietro Cortelli, Maria Guarino, Francesca Vaglio, Maria Naddeo, Maria Naddeo, Barbara Sinigaglia, Luca Zazzeroni, Serafina Guadagnuolo, Enrica Tomassini, Salvatore Nicola Bertuccio, Daria Messelodi, Manuela Ferracin, Massimiliano Bonafè, Pier Luigi Zinzani, Pier Luigi Zinzani, Francesca Bonifazi

“…These latter also showed increased levels of EVs carrying CD14+ and CD45+ myeloid markers, of the myeloid chemokine CXCL-9, as well of the MDSC-secreted cytokine IL-10. …”
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Effects of ovarian stimulation protocols on outcomes of assisted reproductive technology in adenomyosis women: a retrospective cohort study by Li Ge, Yexing Li, Yexing Li, Yexing Li, Yexing Li, Yexing Li, Yexing Li, Yexing Li, Shengnan Guan, Shengnan Guan, Shengnan Guan, Shengnan Guan, Shengnan Guan, Shengnan Guan, Shengnan Guan, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen

“…ObjectiveTo evaluate the effects of different ovarian stimulation protocols on in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes in infertile women with adenomyosis.MethodsWe carried out a retrospective cohort study among infertile women with adenomyosis receiving IVF/ICSI treatment, including 257 fresh embryo transfer (ET) cycles and 305 frozen embryo transfer (FET) cycles. …”
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A multicomponent intervention to reduce daily sitting time in office workers: the SMART Work & Life three-arm cluster RCT by Edwardson Charlotte L, Maylor Benjamin D, Biddle Stuart JH, Clemes Stacy A, Cox Edward, Davies Melanie J, Dunstan David W, Eborall Helen, Granat Malcolm H, Gray Laura J, Hadjiconstantinou Michelle, Healy Genevieve N, Jaicim Nishal Bhupendra, Lawton Sarah, Mandalia Panna, Munir Fehmidah, Richardson Gerry, Walker Simon, Yates Thomas, Clarke-Cornwell Alexandra M

“…Limitations The study was carried out in one sector, limiting generalisability. …”
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Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation by Janet A Wilson, Tony Fouweather, Deborah D Stocken, Tara Homer, Catherine Haighton, Nikki Rousseau, James O’Hara, Luke Vale, Rebecca Wilson, Sonya Carnell, Scott Wilkes, Jill Morrison, Kim Ah-See, Sean Carrie, Claire Hopkins, Nicola Howe, Musheer Hussain, Lyndsay Lindley, Kenneth MacKenzie, Lorraine McSweeney, Hisham Mehanna, Christopher Raine, Ruby Smith Whelan, Frank Sullivan, Alexander von Wilamowitz-Moellendorff, Dawn Teare

“…There is pressure on doctors to limit the number of tonsillectomies carried out. At the same time, emergency hospital admissions for adults with severe throat infections have been increasing. …”
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A parametric study on design and characteristics of stepwise-built functionally graded Hydroxyapatite/Titanium by Siti Nur Sakinah, Jamaludin

“…Several numerical studies for HA/Ti FGM plate were then carried out using analysis system (ANSYS) software and rule of mixture (ROM) formulations to verify the basis of the present model. …”
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Development of sugar palm fibre reinforced thermoplastic polyurethane composites by Abbas, Mohammed Ausama Al-Sarraf

“…The synthesis of SPF fibre and TPU was carried out using an extruder and the resulting material was compressed in the mould using compression moulding at 190 °C. …”
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ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood–brain barrier integrity after traumatic brain injury by Shan Meng, Hui Cao, Yichen Huang, Ziyu Shi, Jiaying Li, Yana Wang, Yue Zhang, Shuning Chen, Hong Shi, Yanqin Gao

“…Methods We employed the CRIPR/Cas9 system to generate a transgenic mouse model carrying the ASK1-K716R mutation, aming to investigate the functional implications of this specific mutant. …”
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The Effect of Agronomical Management on the Growth Characteristics of the Forgotten Cannabis (Cannabis sativa L.) Plant in the Semi-Arid Climate by Hamed Javadi, Seyed Gholam Reza Moosavi, Nasrin Farahmandrad

“…Material and MethodsThe current research was carried out in Center of Agriculture and Natural Resources Research if South Khorasan, located at 59′ 13° east longitude and 53° 32′north latitude, and 1491m above sea level. …”
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EVALUACIÓN DEL MERCADO DE OPCIONES SOBRE TASAS DE CAMBIO: PERSPECTIVAS PARA UNA MEJOR UTILIZACIÓN by Iván Darío Ochoa, Cristina González

“…So this article focuses on the investigation done about the reasons why the mayor Colombian import/export companies had not progressed in forex hedging even though there is an increasing risk because of the mentioned volatility. Investigations carried out on those topics above said were complemented with the study of the variables that determine the market price of options allowed to conclude about the principal reason against developing a strong culture for hedging against forex risk although this risk has been growing day by day. …”
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Efficacy of Follow-up Monitoring for Patients with Very High Cardiovascular Risk in the Omsk Region by Olga Yu. Korennova, Inna V. Druk, Svetlana P. Podolnaya, Marina V. Savchenko, Yulia E. Yuhina, Lyudmila V. Shukil, Elena A. Ryapolova

“…A clinical-expert analysis of 1502 final clinical reportsof patients who completed follow-up after one year was carried out. The patients’ adherence to dispensary observation, achievementof the target values of the main risk factors, total one-year mortality, frequency of recurrent cardiovascular events and occurrence ofadverse events, primary disability were determined.Results and discussion. …”
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Pengaruh Perendaman dengan Asam Cuka dan Sodium Bikarbonat, serta Perlakuan Blansing terhadap Karakteristik Keripik Kulit Ikan Patin (Pangasius hypophthalmus) by Theresia Dwi Suryaningrum, Suryanti Suryanti, Rodiah Nurbaya Sari, Ema Hastarini, Diah Lestari Ayudiarti

“…As a control, skin that was only blanched and without treatment was also observed. The experiment was carried out with 3 replications. The results showed that the combination of soaking in 1% (w/v) NaHCO3 solution and blanching in hot water at 70-80°C for 2 minutes resulted in catfish skin chips that had the most favorable appearance, aroma, crispness, and overall acceptance by the panelists. …”
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