Identification of novel players implicated in replication-dependent and independent DNA interstrand crosslink (ICL) repair by Yaprianto, K

“…One of the most deleterious types of DNA lesions, interstrand crosslink (ICL), occurs when a crosslinking agent forms covalent bonds with both strands of the double helix and tethers them together. The most well-studied among ICL repair pathways is the Fanconi Anaemia (FA) pathway, the disruption of which gives rise to a disorder of the same name. …”

Molecular Dynamics Simulation of the Interaction between Graphene Oxide Quantum Dots and DNA Fragment by Lingxiao Wu, Pengzhen Zhang, Hanxing Zhou, Jing Li, Xin Shen, Tianyu Li, Zhe Kong, Wei Hu, Yongjun Zhang

“…This interaction way damaged the double helix structure of DNA seriously. We also compare the different functional groups of -1COOH. …”
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Design and Experiment of Profiling Furrow-Ridge Terrain by Cane Leaf-Chopping and Returning Machine by Biao Zhang, Cheng Gao, Weimin Shen, Baoshan Chen

“…The leaves piled at furrow sole are intensively collected and fed into the whirling space by the flexible hook teeth assembly, and are cooperatively broken by the unequal-length swing blades densely arranged along the double helix. Based on the measured topographic trends and dynamic analysis of the leaf-shredding process, experimental factors affecting profiling cutting and picking capabilities of the main components were determined. …”
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Four-dimensional multi-particle tracking in living cells based on lifetime imaging by Chen Danni, Li Heng, Yu Bin, Qu Junle

“…Herein, we propose a method of simultaneously monitoring changes in spatial positions and the local environment related to the fluorescence lifetime, i.e., four-dimensional (4D) multi-particle parallel-tracking in living cells. Based on double-helix point spread function (DH-PSF) microscopy and streak camera, the method combines three-dimensional (3D) localization methods and fluorescence lifetime imaging. …”
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Scaffold Hopping and Structural Modification of NSC 663284: Discovery of Potent (Non)Halogenated Aminobenzoquinones by Nilüfer Bayrak, Belgin Sever, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN

“…<b>PQ2</b> is also bound to the minor groove of the double helix of DNA. Based on computational pharmacokinetic studies, <b>PQ2</b> possessed a remarkable drug-like profile, making it a potential anti-leukemia drug candidate for future studies.…”
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Four common vitamin D receptor polymorphisms and coronary artery disease susceptibility: A trial sequential analysis. by Xiaofei Yan, Yuzhen Wei, Dan Wang, Jiangtao Zhao, Kui Zhu, Yuan Liu, Hailong Tao

“…The RNAfold analysis indicated the mutant G allele of the rs1544410 polymorphism was easier to disperse from the DNA double helix structure and may have a potential crucial role in the VDR transcription process.…”
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Effects of Twin-screw Extrusion Temperatures on Structure and Physicochemical Properties of Corn Starch by XU Xin, GAO Wei, KANG Xue-min, CUI Bo

“…As the temperature increased, the content of amylose increased, and the relative crystallinity (RC) and double-helix order (DO) decreased, indicating that the long-range and short-range ordered structures of corn starch were destroyed during heating. …”
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Assessing B-Z DNA Transitions in Solutions via Infrared Spectroscopy by Mengmeng Duan, Yalin Li, Fengqiu Zhang, Qing Huang

“…Z-DNA refers to the left-handed double-helix DNA that has attracted much attention because of its association with some specific biological functions. …”
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Computational, spectroscopic, sensor and biological studies of Cu(II) complex of Fluoro substituted Schiff base by Chinnaraj Kanagavalli, Manivannan Kalanithi, Shunmugasundaram Gurusamy, Radhakrishnan Nandini Asha, Nagaraj Menaka Megtalin, Murugesan Sankarganesh

“…Moreover, the binding ability of FHPB and Cu[FPB]2 were demonstrated by molecular docking and it evidences the strong binding with CT-DNA double helix.…”
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Flanking monomer repeats define lower context complexity of sites containing single nucleotide polymorphisms in the human genome by N. S. Safronova, M. P. Ponomarenko, I. I. Abnizova, G. V. Orlova, I. V. Chadaeva, Y. L. Orlov

“…The presence of poly-A tracks might be associated with an increased probability of double helix DNA breaks around mutable loci and following fixation of nucleotide changes. …”
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The Current Progress of Tetrahedral DNA Nanostructure for Antibacterial Application and Bone Tissue Regeneration by Hong S, Jiang W, Ding Q, Lin K, Zhao C, Wang X

“…Furthermore, functional molecules can be easily modified at the vertices of DNA tetrahedron, DNA double helix structure, DNA tetrahedral arms or DNA tetrahedral cage structure, enabling TDN to be used as a nanocarrier for a variety of biological applications, including targeted therapies, molecular diagnosis, biosensing, antibacterial treatment, antitumor strategies, and tissue regeneration. …”
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Four common vitamin D receptor polymorphisms and coronary artery disease susceptibility: A trial sequential analysis by Xiaofei Yan, Yuzhen Wei, Dan Wang, Jiangtao Zhao, Kui Zhu, Yuan Liu, Hailong Tao

“…The RNAfold analysis indicated the mutant G allele of the rs1544410 polymorphism was easier to disperse from the DNA double helix structure and may have a potential crucial role in the VDR transcription process. …”
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Study on water fraction of oil–gas–water three-phase flow based on electrical methods by Kang Chen, Xiao Wang, Huaiwu Peng, Wei Liu, Pengfei Chen, Long Wen

“…Under the slug flow pattern, the two measurement results of the double-ring conductivity probe and the double-helix capacitance probe were compared. It is found that the double-ring conductivity probe can clearly and accurately reflect the change of the flow pattern in the pipe.…”
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The Crystal Structure of a Junction Between Two Z-DNA Helices by Rich, Alexander, de Rosa, Matteo, de Sanctis, Daniele, Rosario, Ana Lucia, Archer, Margarida, Athanasiadis, Alekos, Carrondo, Maria Armenia

“…The double helix of DNA, when composed of dinucleotide purine-pyrimidine repeats, can adopt a left-handed helical structure called Z-DNA. …”
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Unveiling the retrogradation mechanism of a novel high amylose content starch-Pouteria campechiana seed by Wanru Luo, Bo Li, Yanjun Zhang, Lehe Tan, Chi Hu, Chongxing Huang, Zhanpeng Chen, Lijie Huang

“…Pearson correlation indicated that, as retrogradation days increased, values of α-1,4-glycosidic bond, A chains, double helix, V-type polymorphism, Mw, relative crystallinity (Rc) and short-range order gradually significantly increased, and B1 chains, B3 + chains values gradually significantly dropped (p < 0.05). …”
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Evaluation of Viscosity Changes and Rheological Properties of Diutan Gum, Xanthan Gum, and Scleroglucan in Extreme Reservoirs by Xin Gao, Lixin Huang, Jianlong Xiu, Lina Yi, Yongheng Zhao

“…Rheological tests showed that the unique double-helix structure of diutan gum and the rigid triple-helix structure of scleroglucan caused them to have better viscoelastic properties than xanthan gum. …”
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Establishment of a Rapid LAMP Assay for <i>Aeromonas hydrophila</i> and Comparison with the Application of qPCR by Zihui Gao, Chunhua Yang, Xiaobo Zhang, Bing Hu, Huang Zhang, Zhihong Zhang, Wendong Kuang, Qiuyue Zheng, Jijuan Cao

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Deep Splicer: A CNN Model for Splice Site Prediction in Genetic Sequences by Elisa Fernandez-Castillo, Liliana Ibeth Barbosa-Santillán, Luis Falcon-Morales, Juan Jaime Sánchez-Escobar

“…DNA is an organic molecule of two complementary strands of four different nucleotides wound up in a double helix. These nucleotides are adenine (A), thymine (T), guanine (G), and cytosine (C). …”
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Terminal Mono- and Bis-Conjugates of Oligonucleotides with <i>Closo</i>-Dodecaborate: Synthesis and Physico-Chemical Properties by Darya S. Novopashina, Mariya A. Vorobyeva, Alexander A. Lomzov, Vladimir N. Silnikov, Alya G. Venyaminova

“…According to circular dichroism spectroscopy results, two terminal <i>closo</i>-dodecaborate residues cause a prominent structural rearrangement of complementary complexes with a substantial shift from the B-form to the A-form of the double helix. The revealed changes of key characteristics of oligonucleotides caused by incorporation of terminal boron clusters, such as the increase of hydrophobicity, change of duplex stability, and prominent structural changes for DNA conjugates, should be taken into account for the development of antisense oligonucleotides, siRNAs, or aptamers bearing boron clusters. …”
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Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile by Park, Ga Young, Wilson, Justin Jeff, Song, Ying, Lippard, Stephen J.

“…Monofunctional platinum(II) complexes of general formula cis-[Pt(NH3)2(N-heterocycle)Cl]Cl bind DNA at a single site, inducing little distortion in the double helix. Despite this behavior, these compounds display significant antitumor properties, with a different spectrum of activity than that of classic bifunctional cross-linking agents like cisplatin. …”
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