Showing 21 - 40 results of 1,134 for search '"The Hallmarks of Cancer"', query time: 0.11s Refine Results
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    Investigating small non-coding RNA regulating the hallmarks of cancer by Dhawan, A

    Published 2018
    “…In a second chapter, I use this methodology to generate a statistical mapping from miRNA to gene signatures for the hallmarks of cancer. I show that there is a core set of miRNA statistically associated with these gene signatures, which preferentially and, in some cases, exclusively, anti-correlate across cancer types with a subset of tumour suppressor genes, such as <em>PTEN, FAT4,</em> and <em>CDK12</em>.…”
    Thesis
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    Ancient genes establish stress-induced mutation as a hallmark of cancer. by Luis Cisneros, Kimberly J Bussey, Adam J Orr, Milica Miočević, Charles H Lineweaver, Paul Davies

    Published 2017-01-01
    “…Reversion to a stress-induced mutational response is a hallmark of cancer that allows for effectively searching "protected" genome space where genes causally implicated in cancer are located and underlies the high adaptive potential and concomitant therapeutic resistance that is characteristic of cancer.…”
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    Roles of NRF3 in the Hallmarks of Cancer: Proteasomal Inactivation of Tumor Suppressors by Akira Kobayashi

    Published 2020-09-01
    “…Collectively, the evidence indicates that NRF3 confers cells with six so-called “hallmarks of cancer”, implying that it exhibits cancer driver gene-like function. …”
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    Aspirin and the metabolic hallmark of cancer: novel therapeutic opportunities for colorectal cancer by Ashley J. Hoskin, Amy K. Holt, Danny N. Legge, Tracey J. Collard, Ann C. Williams, Emma E. Vincent

    Published 2023-08-01
    “…This review focuses on the emerging role of aspirin as a regulator of metabolic reprogramming, an essential “hallmark of cancer” required to support the increased demand for biosynthetic intermediates needed for sustained proliferation. …”
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    Lung Cancer Gene Regulatory Network of Transcription Factors Related to the Hallmarks of Cancer by Beatriz Andrea Otálora-Otálora, Liliana López-Kleine, Adriana Rojas

    Published 2023-01-01
    “…Our results indicate that lung cancer has unique and common deregulated genes and transcription factors with pulmonary arterial hypertension, co-expressed and regulated in a coordinated and cooperative manner by the transcriptional regulatory network that might be associated with critical biological processes and signaling pathways related to the acquisition of the hallmarks of cancer, making them potentially relevant tumor biomarkers for lung cancer early diagnosis and targets for the development of personalized therapies against lung cancer.…”
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    MmuPV1 E6 induces cell proliferation and other hallmarks of cancer by James C. Romero-Masters, Laura K. Muehlbauer, Mitchell Hayes, Miranda Grace, Evgenia Shishkova, Joshua J. Coon, Karl Munger, Paul F. Lambert

    Published 2023-12-01
    “…Collectively, our results suggest that MmuPV1 E6 is a major driver of multiple hallmarks of cancer in MmuPV1’s natural host cells, mouse keratinocytes.IMPORTANCEThe Mus musculus papillomavirus 1 (MmuPV1) E6 and E7 proteins are required for MmuPV1-induced disease. …”
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