Pregabalin for acute and chronic pain in adults. by Moore, R, Straube, S, Wiffen, P, Derry, S, McQuay, H

“…DATA COLLECTION AND ANALYSIS: Two independent review authors extracted data and assessed trial quality. …”

Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial by Thwaites, GE, Scarborough, M, Szubert, AJ, Nsutebu, E, Tilley, R, Greig, J, Wyllie, SA, Wilson, P, Auckland, C, Cairns, J, Ward, D, Lal, P, Guleri, A, Jenkins, N, Sutton, J, Wilselka, M, Armando, G-R, Graham, C, Chadwick, PR, Barlow, G, Gordon, NC, Young, B, Meisner, S, McWhinney, P, Price, DA, Harvey, D, Nayar, D, Jeyaratnam, D, Planche, T, Minton, J, Hudson, F, Hopkins, S, Williams, J, Torok, ME, Llewelyn, MJ, Edgeworth, JD, Walker, AS

“…The primary outcome was time to bacteriologically confirmed treatment failure or disease recurrence, or death (all-cause), from randomisation to 12 weeks, adjudicated by an independent review committee masked to the treatment. Analysis was intention to treat. …”

Strategies for nevirapine initiation in HIV-infected children taking pediatric fixed-dose combination "baby pills" in Zambia: a randomized controlled trial. by Mulenga, V, Cook, A, Walker, A, Kabamba, D, Chijoka, C, Ferrier, A, Kalengo, C, Kityo, C, Kankasa, C, Burger, D, Thomason, M, Chintu, C, Gibb, D

“…Twenty-two children died (12 in FD and 10 in DE), 1 FD and 5 DE children at <4 weeks; none were considered to be drug related by independent review. CONCLUSIONS: Rash was more frequent with FD nevirapine, but 88% had no clinical toxicity; elevated AST or ALT levels were transient and resolved spontaneously, suggesting that routine laboratory monitoring has limited value. …”

The prevalence, risk factors and outcomes of anaemia in South African pregnant women: a protocol for a systematic review and meta-analysis by Vinogrin Dorsamy, Chauntelle Bagwandeen, Jagadesa Moodley

“…The articles obtained by these searches will be analysed for causative factors, severity and outcomes by a parallel and independent review team, using suitable eligibility criteria. …”
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Improving patient-provider communication about chronic pain: development and feasibility testing of a shared decision-making tool by Nananda Col, Stephen Hull, Vicky Springmann, Long Ngo, Ernie Merritt, Susan Gold, Michael Sprintz, Noel Genova, Noah Nesin, Brenda Tierman, Frank Sanfilippo, Richard Entel, Lori Pbert

“…Trial registration This study was approved by the University of New England Independent Review Board for the Protection of Human Subjects in Research (012616–019) and was registered with ClinicalTrials.gov (protocol ID: NCT03425266) prior to enrollment. …”
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The Conceptualization and Measurement of Research Impact in Primary Health Care: Protocol for a Rapid Scoping Review by Monica Aggarwal, Brian G Hutchison, Kristina M Kokorelias, Vivian R Ramsden, Noah M Ivers, Andrew Pinto, Ross E G Uphsur, Sabrina T Wong, Nick Pimlott, Steve Slade

“…The collected papers will undergo a 2-stage independent review process based on predetermined inclusion criteria. …”
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Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: final update of the pivotal ERIVANCE BCC study by Aleksandar Sekulic, Michael R. Migden, Nicole Basset-Seguin, Claus Garbe, Anja Gesierich, Christopher D. Lao, Chris Miller, Laurent Mortier, Dedee F. Murrell, Omid Hamid, Jorge F. Quevedo, Jeannie Hou, Edward McKenna, Natalie Dimier, Sarah Williams, Dirk Schadendorf, Axel Hauschild, for the ERIVANCE BCC Investigators

“…Abstract Background In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration–approved Hedgehog pathway inhibitor, showed objective response rates (ORRs) by independent review facility (IRF) of 30% and 43% in metastatic basal cell carcinoma (mBCC) and locally advanced BCC (laBCC), respectively. …”
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Injury-related gaining momentum as external causes of deaths in Ethiopian health and demographic surveillance sites: evidence from verbal autopsy study by Kassahun Alemu Gelaye, Fasil Tessema, Befikadu Tariku, Semaw Ferede Abera, Alemseged Aregay Gebru, Nega Assefa, Desalew Zelalem, Melkamu Dedefo, Mekdes Kondal, Mesfin Kote, Mitike Molla Sisay, Wubegzier Mekonnen, Mamo Wubshet Terefe, Gashaw Andargie Biks, Firehywot Eshetu, Mulumebet Abera, Yoseph Fekadu, Gessessew Bugssa Hailu, Etsehiwot Tilahun, Yihunie Lakew

“…Disagreed cases sent to third physician for independent review and diagnosis. The final cause of death considered when two of the three physicians assigned underlying cause of death; otherwise, labeled as undetermined. …”
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Efficacy and safety analysis of hypofractionated and conventional fractionated radiotherapy in postoperative breast cancer patients by Yongkai Lu, Beina Hui, Di Yang, Yi Li, Binglin Li, Luping Zhou, Lei Xu, Fengwen Tang, Wei Wang, Ruijuan Chen, Dongli Zhao

“…Methods This study involved a systematic and independent review of relevant research articles published in reputable databases such as PubMed, Embase, Cochrane Library, and Web of Science. …”
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Twelve-Month Results from a Prospective Clinical Study Evaluating the Efficacy and Safety of Cellular Bone Allograft in Subjects Undergoing Lumbar Spinal Fusion by Joshua Wind, Daniel Park, Todd Lansford, Pierce Nunley, Timothy Peppers, Anthony Russo, Hamid Hassanzadeh, Jonathan N. Sembrano, Jung Yoo, Jonathan Sales

“…Radiographic fusion status was assessed by an independent review of dynamic radiographs and CT scans. …”
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Community interventions and strategies for caries control in Latin American and Caribbean countries by Antônio Pedro RICOMINI FILHO, Bertha Angélica CHÁVEZ, Rodrigo Andrés GIACAMAN, Paulo FRAZÃO, Jaime Aparecido CURY

“…A critical literature review was carried out in a systematic manner that included defined search strategies, independent review of the identified publications, and compilation of results in this report. …”
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Disease-Specific Health Disparities: A Targeted Review Focusing on Race and Ethnicity by Mark R. Cullen, Adina R. Lemeshow, Leo J. Russo, David M. Barnes, Yaa Ababio, Aida Habtezion

“…After primary review of each condition by one author, another undertook an independent review. Differences between reviewers were resolved through discussion. …”
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A pivotal bridging study of lurbinectedin as second-line therapy in Chinese patients with small cell lung cancer by Ying Cheng, Chunjiao Wu, Lin Wu, Jun Zhao, Yanqiu Zhao, Lulu Chen, Ying Xin, Liang Zhang, Pinhua Pan, Xingya Li, Juan Li, Xiaorong Dong, Ke Tang, Emei Gao, Fei Yu

“…No treatment-related deaths occurred. The Independent Review Committee (IRC)-assessed ORR was 45.5% (95% CI 26.9–65.3). …”
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CanCOG^®: Cultural Adaptation of the Evidence-Based UCLA Cognitive Rehabilitation Intervention Program for Cancer Survivors in Portugal by Ana F. Oliveira, Milaydis Sosa-Napolskij, Ana Torres, Diâner Felipe Queiroz, Ana Bártolo, Helena Sousa, Sara Monteiro, Kathleen Van Dyk, Linda M. Ercoli, Isabel M. Santos

“…Nine steps were implemented for this cultural adaptation: needs assessment, initial contacts, translation, cultural adaptation, independent review by a panel of experts (n = 6), focus group discussions with cancer survivors (n = 11), systematization of inputs and improvement of the final materials, fidelity check, and preliminary acceptability assessment. …”
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Mobile Apps to Support Mental Health Response in Natural Disasters: Scoping Review by Nwamaka Alexandra Ezeonu, Attila J Hertelendy, Medard Kofi Adu, Janice Y Kung, Ijeoma Uchenna Itanyi, Raquel da Luz Dias, Belinda Agyapong, Petra Hertelendy, Francis Ohanyido, Vincent Israel Opoku Agyapong, Ejemai Eboreime

“…The initial titles and abstracts of the unique papers were screened by 2 independent review authors. Full texts of the selected papers that met the inclusion criteria were reviewed by the 2 independent reviewers. …”
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Indirect treatment comparison of bevacizumab + interferon-α-2a vs tyrosine kinase inhibitors in first-line metastatic renal cell carcinoma therapy by Gerald HJ Mickisch, Björn Schwander, Bernard Escudier, et al

“…These targeted therapies are currently competing to be primary choice; hence, in the absence of direct head-to-head comparison, there is a need for valid indirect comparison assessment.Methods: Standard indirect comparison methods were applied to independent review PFS data of the pivotal Phase III trials, to determine indirect treatment comparison hazard-ratios (HR) with 95% confidence intervals (95% CI). …”
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Differential attainment at MRCS according to gender, ethnicity, age and socioeconomic factors: a retrospective cohort study by Ellis, Ricky, Brennan, Peter A., Lee, Amanda J., Scrimgeour, Duncan S. G., Cleland, Jennifer

“…Objective: A recent independent review on diversity and inclusivity highlighted concerns that barriers to surgical career progression exist for some groups of individuals and not others. …”
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Translating Suicide Safety Planning Components Into the Design of mHealth App Features: Systematic Review by Kim Gryglewicz, Victoria L Orr, Marissa J McNeil, Lindsay A Taliaferro, Serenea Hines, Taylor L Duffy, Pamela J Wisniewski

“…We conducted an analysis of the literature to evaluate how the apps incorporated SPI components and examined similarities and differences among the apps by conducting a comparative analysis of app features. An independent review of SPI components and app features was conducted by downloading the available apps. …”
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Transitions for older people with learning disabilities and behaviours that challenge others, and their family carers: a merged protocol for two rapid scoping reviews of evidence by J. Vseteckova, J. Jordan, E. Tilley, M. Larkin, S. Ryan, L. M. Wallace

“…One reviewer will extract data, with an independent review undertaken by the research team. Critical appraisal will depend on the nature of included evidence. …”
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Impact of Bevacizumab Being Skipped due to Adverse Events of Special Interest for Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus... by Masatoshi Kudo, Kaoru Tsuchiya, Yu-Yun Shao, Richard S. Finn, Peter R. Galle, Michel Ducreux, Ann-Lii Cheng, Tatsuya Yamashita, Hironori Koga, Ryosuke Take, Kyoko Yamada, Takashi Asakawa, Yuki Nakagawa, Masafumi Ikeda

“…PFS was evaluated per independent review facility (IRF)-assessed Response Evaluation Criteria in Solid Tumours (RECIST) version 1.1 and HCC-modified RECIST (IRF-HCC mRECIST). …”
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