Patient-reported outcome measures in pediatric palliative care—a protocol for a scoping review by Heidi Holmen, Anette Winger, Simen A. Steindal, Charlotte Castor, Lisbeth Gravdal Kvarme, Kirsti Riiser, Kari L. Mariussen, Anja Lee

“…Covidence will facilitate the independent review of eligible citations, and data will be extracted and presented descriptively, and thematically analyzed using NVivo. …”
Get full text

Prevalence of premature rupture of membrane and its associated factors among pregnant women in Ethiopia: A systematic review and meta-analysis by Getahun Tiruye, Kassiye Shiferaw, Abera Kenay Tura, Adera Debella, Abdulbasit Musa

“…Methods: PubMed/Medline, Scopus, and African journal online databases and Google Scholar were searched for articles published in the English language. Independent review authors selected and screened studies. …”
Get full text

Sutures versus staples for wound closure in orthopaedic surgery: a randomized controlled trial by Shantz Jesse A, Vernon James, Leiter Jeff, Morshed Saam, Stranges Gregory

“…The primary outcome measure will be a composite all-cause wound complication outcome measure composed of: infection, wound drainage, wound necrosis, blistering, dehiscence, suture abscess and material sensitivity reaction. An independent review board blinded to treatment assignment will adjudicate suspected complications based on clinical data. …”
Get full text

Increasing transparency in indirect treatment comparisons: is selecting effect modifiers the missing part of the puzzle? A review of methodological approaches and critical consider... by Andreas Freitag, Laura Gurskyte, Grammati Sarri

“…Researchers and manufacturers are also encouraged to improve transparent reporting and justification of their selection of EMs to allow for an independent review of the set of factors being considered for adjustment. …”

The safety and tolerability of candesartan cilexetil in CHF by Erland Erdmann, Michael George, Bernhard Voet, Glyn Belcher, Doris Kolb, Siegfried Hiemstra, Monika Pietrek, Peter Held

“…None was designed as an endpoint trial. A blinded, independent review of all adverse event data was performed to assess all-cause mortality and unexpected deaths, and hospitalisations for acute deterioration of CHF, chronic progression of CHF, other intercurrent events, or accidental injury/attempted suicide. …”
Get full text

Fluvoxamine versus other anti-depressive agents for depression. by Omori, I, Watanabe, N, Nakagawa, A, Cipriani, A, Barbui, C, McGuire, H, Churchill, R, Furukawa, T

“…DATA COLLECTION AND ANALYSIS: Two independent review authors inspected citations and abstracts, obtained papers, extracted data and assessed the risk of bias of included studies. …”

Effectiveness of Social Cognitive Theory–Based Interventions for Glycemic Control in Adults With Type 2 Diabetes Mellitus: Protocol for a Systematic Review and Meta-Analysis by Smith, Yvonne, Garcia-Torres, Rosalia, Coughlin, Steven S, Ling, Jiying, Marin, Terri, Su, Shaoyong, Young, Lufei

“…Screening and data collection will be performed in multiple stages with three reviewers as follows: (1) an independent review of titles/abstracts, (2) a full review, and (3) data collection with alternating teams of two reviewers for disputes to be resolved by a third reviewer. …”
Get full text

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma by Shinichi Makita, Go Yamamoto, Dai Maruyama, Yuki Asano‐Mori, Daisuke Kaji, Revathi Ananthakrishnan, Ken Ogasawara, Lara Stepan, Claudia Schusterbauer, Nils Rettby, Jens Hasskarl, Koji Izutsu

“…The primary efficacy endpoint was objective response rate (ORR; Lugano 2014 criteria) assessed by an independent review committee. Fourteen patients were enrolled; 10 received liso‐cel infusion (median time to liso‐cel availability, 23 days) and were evaluable at data cutoff (median follow‐up, 12.5 months). …”
Get full text

Integration between Novel Imaging Technologies and Modern Radiotherapy Techniques: How the Eye Drove the Chisel by Giulio Francolini, Ilaria Morelli, Maria Grazia Carnevale, Roberta Grassi, Valerio Nardone, Mauro Loi, Marianna Valzano, Viola Salvestrini, Lorenzo Livi, Isacco Desideri

“…Three independent authors (GF, IM and ID) performed an independent review focusing on these issues. Key references were derived from a PubMed query. …”
Get full text

Comparison of Efficacy and Safety of Brigatinib in First-Line Treatments for Patients with Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: A Systematic Review and I... by Yongfeng Yu, Fanfan Zhu, Wenxin Zhang, Shun Lu

“…In intent-to-treat (ITT) patients, brigatinib significantly prolonged blinded independent review committee-assessed PFS compared with crizotinib (HR: 0.48, 95% CI: 0.35 to 0.66) and ceritinib (HR: 0.38, 95% CI: 0.23, 0.60) and had a comparable PFS with other 2nd-generation ALK inhibitors. …”
Get full text

IMbrave150: Efficacy and Safety of Atezolizumab Plus Bevacizumab vs Sorafenib in Patients With Barcelona Clinic Liver Cancer Stage B Unresectable Hepatocellular Carcinoma—An Explor... by Masatoshi Kudo, Richard S. Finn, Peter R. Galle, Andrew X. Zhu, Michel Ducreux, Ann-Lii Cheng, Masafumi Ikeda, Kaoru Tsuchiya, Ken-ichi Aoki, Jing Jia, Riccardo Lencioni

“…Co-primary endpoints were overall survival (OS) and progression-free survival (PFS) per independent review facility (IRF)–assessed Response Evaluation Criteria in Solid Tumours (RECIST) version 1.1 in the BCLC Stage B subgroup. …”
Get full text

Test reliability and comparability of paper and Chinese electronic version of the western Ontario and McMaster University osteoarthritis index: protocol for a randomised controlled... by Yujie Zhang, Yuxin Zheng, Ye Zhao, Kaoqiang Liu, Yongli Chai, Fen Lin, Hongsheng Zhan, Weian Yuan

“…The primary outcome of the study is the mean score difference in WOMAC, and the secondary outcomes are the score differences in WOMAC subscales: pain, stiffness and physical function.Ethics and dissemination The protocol has been approved by the Independent Review Board of SGH (approval number: 2020-814-21-01). …”
Get full text

A Cost-Effectiveness Analysis of the Integration of Robotic Spine Technology in Spine Surgery by Richard Philip Menger, Amey R. Savardekar, Frank Farokhi, Anthony Sin

“…Fifty-eight (10.4%) were MIS fusions. Independent review determined an additional ~10% cases (50) to be candidates for MIS fusion. …”
Get full text

Effectiveness of Technology-Enabled Knowledge Translation Strategies in Improving the Use of Research in Public Health: Systematic Review by Brown, Alison, Barnes, Courtney, Byaruhanga, Judith, McLaughlin, Matthew, Hodder, Rebecca K, Booth, Debbie, Nathan, Nicole, Sutherland, Rachel, Wolfenden, Luke

“…A hand search of 2 journals (Implementation Science and Journal of Medical Internet Research) and a gray literature search were also conducted. Pairs of independent review authors screened studies, assessed the risk of bias, and extracted data from relevant studies. …”
Get full text

Patient and healthcare provider reported barriers and enablers to virtual or remote-only follow-up models for cardiovascular implantable electronic devices: protocol for a qualitat... by Shannon E. Kelly, Tammy J. Clifford, Becky Skidmore, David Birnie, Ratika Parkash, George A. Wells

“…Screening will be completed by two independent review authors. Original research articles having a qualitative component (i.e., qualitative, mixed-, or multi-method) are eligible. …”
Get full text

When is a Vestibular Aqueduct Enlarged? by Nathaniel W. Yang

“…The formal radiologic interpretation of the scan stated that the vestibular aqueducts were not enlarged. However, independent review of the axial CT images appeared to indicate the presence of enlarged vestibular aqueducts. …”
Get full text

A chart review tool to systematically assess the safety of prehospital care for children with out‐of‐hospital cardiac arrest by Amanda Schoonover, Carl O. Eriksson, Thuan Nguyen, Garth Meckler, Matthew Hansen, Tabria Harrod, Jeanne‐Marie Guise

“…We randomly selected 28 charts for independent review by 2 expert reviewers who determined the presence or absence of a severe ASE for each care episode and identified the domain of care and preventability for each ASE. …”
Get full text

From ASCEND-5 to ALUR to ALTA-3, an Anti-Climactic End to the Era of Randomized Phase 3 Trials of Next-Generation ALK TKIs in the Crizotinib-Refractory Setting by Lee AT, Ou SI

“…ALTA-3 compared brigatinib to alectinib, showing that both achieved near identical blinded independent review committee (BIRC)-assessed progression-free survival (PFS) (19.2– 19.3 months). …”
Get full text

The effect of antenatal magnesium sulfate on intraventricular hemorrhage in premature infants: a systematic review and meta-analysis by Yousef Moradi, Rozhin Khateri, Ladan Haghighi, Shoaib Dehghani, Shiva Mansouri Hanis, Mehrdad Valipour, Zahra Najmi, Zahra Fathollahy, Meisam Allahmoradi, Kamyar Mansori

“…MethodsTwo review authors independently searched all randomized clinical trials from international databases, including Medline (PubMed), Web of Sciences, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), and Research Registers of ongoing trials (ClinicalTrials.gov), from January 1989 to August 2017. Two independent review authors were responsible for data collection. …”
Get full text

Clinical Utility of Mobocertinib in the Treatment of NSCLC – Patient Selection and Reported Outcomes by Arnold A, Ganti AK

“…A third phase evaluated patients who had received pre-treatment with platinum-based chemotherapy (PPP) and included an extension cohort (EXCLAIM cohort) which evaluated patients treated previously with 1 or 2 lines of therapy. An Independent Review Committee (IRC) found both cohorts to have similar outcomes in terms of ORR, median time to response, mPFS, and disease progression or death. …”
Get full text