Editorial: Fibrosis and Inflammation in Tissue Pathophysiology by Isotta Chimenti, Isotta Chimenti, Susanne Sattler, Gonzalo del Monte-Nieto, Elvira Forte

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Translating Data Science Results into Precision Oncology Decisions: A Mini Review by Enrico Capobianco, Marco Dominietto

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SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes by Jeroen Pouwels, Nicola De Franceschi, Pia Rantakari, Kaisa Auvinen, Marika Karikoski, Elina Mattila, Christopher Potter, John P. Sundberg, Nancy Hogg, Carl G. Gahmberg, Marko Salmi, Johanna Ivaska

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Randomized feature selection based semi-supervised latent Dirichlet allocation for microbiome analysis by Namitha Pais, Nalini Ravishanker, Sanguthevar Rajasekaran, George Weinstock, Dong-Binh Tran

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Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss by Stephanie A. Mauriac, Thibault Peineau, Aamir Zuberi, Cathleen Lutz, Gwénaëlle S. G. Géléoc

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Toward Modeling Context-Specific EMT Regulatory Networks Using Temporal Single Cell RNA-Seq Data by Daniel Ramirez, Vivek Kohar, Mingyang Lu

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Quantitative trait mapping in Diversity Outbred mice identifies novel genomic regions associated with the hepatic glutathione redox system by Rebecca L. Gould, Steven W. Craig, Susan McClatchy, Gary A. Churchill, Robert Pazdro

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Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia by Xujie Zhao, Ping Wang, Jonathan D. Diedrich, Brandon Smart, Noemi Reyes, Satoshi Yoshimura, Jingliao Zhang, Wentao Yang, Kelly Barnett, Beisi Xu, Zhenhua Li, Xin Huang, Jiyang Yu, Kristine Crews, Allen Eng Juh Yeoh, Marina Konopleva, Chia-Lin Wei, Ching-Hon Pui, Daniel Savic, Jun J. Yang

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System-Level Analysis of Alzheimer’s Disease Prioritizes Candidate Genes for Neurodegeneration by Jeffrey L. Brabec, Montana Kay Lara, Anna L. Tyler, J. Matthew Mahoney, J. Matthew Mahoney

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Thanatomicrobiome composition profiling as a tool for forensic investigation by Wei Zhou, Yingnan Bian

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One reference genome is not enough by Xiaofei Yang, Wan-Ping Lee, Kai Ye, Charles Lee

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TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome by Elizabeth A. Werren, Geneva R. LaForce, Anshika Srivastava, Delia R. Perillo, Shaokun Li, Katherine Johnson, Safa Baris, Brandon Berger, Samantha L. Regan, Christian D. Pfennig, Sonja de Munnik, Rolph Pfundt, Malavika Hebbar, Raúl Jimenez-Heredia, Elif Karakoc-Aydiner, Ahmet Ozen, Jasmin Dmytrus, Ana Krolo, Ken Corning, E. J. Prijoles, Raymond J. Louie, Robert Roger Lebel, Thuy-Linh Le, Jeanne Amiel, Christopher T. Gordon, Kaan Boztug, Katta M. Girisha, Anju Shukla, Stephanie L. Bielas, Ashleigh E. Schaffer

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Mendelian gene identification through mouse embryo viability screening by Pilar Cacheiro, Carl Henrik Westerberg, Jesse Mager, Mary E. Dickinson, Lauryl M. J. Nutter, Violeta Muñoz-Fuentes, Chih-Wei Hsu, Ignatia B. Van den Veyver, Ann M. Flenniken, Colin McKerlie, Stephen A. Murray, Lydia Teboul, Jason D. Heaney, K. C. Kent Lloyd, Louise Lanoue, Robert E. Braun, Jacqueline K. White, Amie K. Creighton, Valerie Laurin, Ruolin Guo, Dawei Qu, Sara Wells, James Cleak, Rosie Bunton-Stasyshyn, Michelle Stewart, Jackie Harrisson, Jeremy Mason, Hamed Haseli Mashhadi, Helen Parkinson, Ann-Marie Mallon, International Mouse Phenotyping Consortium, Genomics England Research Consortium, Damian Smedley

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Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity by Gihyeon Kim, Youngmin Yoon, Jin Ho Park, Jae Won Park, Myung-guin Noh, Hyun Kim, Changho Park, Hyuktae Kwon, Jeong-hyeon Park, Yena Kim, Jinyoung Sohn, Shinyoung Park, Hyeonhui Kim, Sun-Kyoung Im, Yeongmin Kim, Ha Yung Chung, Myung Hee Nam, Jee Young Kwon, Il Yong Kim, Yong Jae Kim, Ji Hyeon Baek, Hak Su Kim, George M. Weinstock, Belong Cho, Charles Lee, Sungsoon Fang, Hansoo Park, Je Kyung Seong

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Integrative deep learning analysis improves colon adenocarcinoma patient stratification at risk for mortalityResearch in context by Jie Zhou, Ali Foroughi pour, Hany Deirawan, Fayez Daaboul, Thazin Nwe Aung, Rafic Beydoun, Fahad Shabbir Ahmed, Jeffrey H. Chuang

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Auriculocondylar syndrome 2 results from the dominant-negative action of PLCB4 variants by Stanley M. Kanai, Caleb Heffner, Timothy C. Cox, Michael L. Cunningham, Francisco A. Perez, Aaron M. Bauer, Philip Reigan, Cristan Carter, Stephen A. Murray, David E. Clouthier

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Multi-omic and multi-species meta-analyses of nicotine consumption by Rohan H. C. Palmer, Chelsie E. Benca-Bachman, Spencer B. Huggett, Jason A. Bubier, John E. McGeary, Nikhil Ramgiri, Jenani Srijeyanthan, Jingjing Yang, Peter M. Visscher, Jian Yang, Valerie S. Knopik, Elissa J. Chesler

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Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma by Aaron M. Taylor, Jiayi M. Sun, Alexander Yu, Horatiu Voicu, Jianhe Shen, Donald A. Barkauskas, Timothy J. Triche, Julie M. Gastier-Foster, Tsz-Kwong Man, Ching C. Lau

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Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy by Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. Varn, Roel G. Verhaak, Junfei Zhao, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea M. Muscat, Eric S. Lipp, Smita K. Nair, Mustafa Khasraw, Katherine B. Peters, Dina Randazzo, John H. Sampson, Roger E. McLendon, Darell D. Bigner, David M. Ashley

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Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers by Mario F. Perez, Marina Yurieva, Spandana Poddutoori, Eric M. Mortensen, Laura E. Crotty Alexander, Adam Williams

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