Using Knock-Out Mutants to Investigate the Adhesion of <i>Staphylococcus aureus</i> to Abiotic Surfaces by Christian Spengler, Friederike Nolle, Nicolas Thewes, Ben Wieland, Philipp Jung, Markus Bischoff, Karin Jacobs

Subjects: “…<i>Staphylococcus aureus</i> knock-out mutants…”
Get full text

Long-Term Evaluation of Retinal Morphology and Function in Rosa26-Cas9 Knock-In Mice by Kabhilan Mohan, Sushil Kumar Dubey, Kyungsik Jung, Rashmi Dubey, Qing Jun Wang, Subhash Prajapati, Jacob Roney, Jennifer Abney, Mark Ellsworth Kleinman

Subjects: Get full text

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells by Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H. De Vos, Emmanuel Valjent, Bálazs Gaszner, Ann Van Eeckhaut, Ilse Smolders, Dimitri De Bundel

Subjects: Get full text

Rapid clonal identification of biallelic CRISPR/Cas9 knock-ins using SNEAK PEEC by Sameer Singh, Anoosha Banerjee, Arnaud Vanden Broeck, Sebastian Klinge

Get full text

Investigations Concerning Improvements of the Knock Out Property of Ceramic Moulds Applied in the Investment Casting Technology by Joanna Kolczyk-Tylka, Jerzy Zych

Subjects: Get full text

Investigation of the effect of ignition position on combustion behavior and knock characteristics by using an optically accessible engine by Sota NAKAMURA, Toshiki KIMURA, Kensuke KUWADA, Yosuke ABE, Akihito KASAI, Akira IIJIMA

Subjects: “…knocking…”
Get full text

Auditory or Audiovisual Stimulation Ameliorates Cognitive Impairment and Neuropathology in ApoE4 Knock-In Mice by Harry Jung, Yeonkyeong Lee, Sang-Hwa Lee, Jong-Hee Sohn

Get full text

Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells by Yuki Kobayashi, Ryuhei Hayashi, Andrew J. Quantock, Kohji Nishida

Subjects: Get full text

Antioxidant Behavioural Phenotype in the <i>Immp2l</i> Gene Knock-Out Mouse by Adam J. Lawther, Jerzy Zieba, Zhiming Fang, Teri M. Furlong, Illya Conn, Hemna Govindaraju, Laura L. Y. Choong, Nigel Turner, Khawar Sohail Siddiqui, Wallace Bridge, Sam Merlin, Tzipi Cohen Hyams, Murray Killingsworth, Valsamma Eapen, Raymond A. Clarke, Adam K. Walker

Get full text

Amelioration of Alzheimer’s Disease by Gut-Pancreas-Liver-Brain Interaction in an App Knock-In Mouse Model by Mayumi Minamisawa, Yuma Sato, Eitarou Ishiguro, Tetsuyuki Taniai, Taiichi Sakamoto, Gota Kawai, Takashi Saito, Takaomi C. Saido

Get full text

Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish by Meredith H Wilson, Stephen C Ekker, Steven A Farber

Get full text

Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells by Liora Jacobs Catane, Ofra Moshel, Yoav Smith, Ben Davidson, Reuven Reich

Get full text

CRISPR/Cas9-mediated knock-in strategy at the Rosa26 locus in cattle fetal fibroblasts. by Yuxuan Xie, Ming Wang, Liang Gu, Yang Wang

“…In this study, we efficiently integrated three targeted vector into the cattle Rosa26 (cRosa26) by CRISPR/Cas9 technology in which EGFP was driven by CAG, EF1a, PGK and cRosa26 endogenous promoter respectively. The CRISPR/Cas9 knock-in system allows highly efficient gene insertion of different expression units at the cRosa26 locus. …”
Get full text

Effect of Spark Ignition Timing and Water Injection Temperature on the Knock Combustion of a GDI Engine by Aqian Li, Zhaolei Zheng

Subjects: Get full text

Involvement of ceramide biosynthesis in increased extracellular vesicle release in Pkd1 knock out cells by Valentina Carotti, Jenny van der Wijst, Eric H. J. Verschuren, Luco Rutten, Nico Sommerdijk, Charlotte Kaffa, Vera Sommers, Juan P. Rigalli, Joost G. J. Hoenderop

Get full text

An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation by Yukiko U. Inoue, Yuki Morimoto, Mayumi Yamada, Ryosuke Kaneko, Kazumi Shimaoka, Shinji Oki, Mayuko Hotta, Junko Asami, Eriko Koike, Kei Hori, Mikio Hoshino, Itaru Imayoshi, Takayoshi Inoue

Subjects: Get full text

Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment by Raquel Brañas Casas, Alessandro Zuppardo, Giovanni Risato, Alberto Dinarello, Rudy Celeghin, Camilla Fontana, Eleonora Grelloni, Alexandru Ionut Gilea, Carlo Viscomi, Andrea Rasola, Luisa Dalla Valle, Tiziana Lodi, Enrico Baruffini, Nicola Facchinello, Francesco Argenton, Natascia Tiso

Get full text

Investigation of Scavenging, Combustion and Knock in a Two-Stroke SI Engine Operated with Gasoline and CNG by S Fontanesi, E Severi, F Bozza, A Gimelli

“…At the end of the simulation process, the 1D knock index is qualitatively compared to results obtained from full 3D knocking analyses for different in-cylinder compositions and spark timings. …”
Get full text

Impaired telomere integrity and rRNA biogenesis in PARN‐deficient patients and knock‐out models by Maname Benyelles, Harikleia Episkopou, Marie‐Françoise O'Donohue, Laëtitia Kermasson, Pierre Frange, Florian Poulain, Fatma Burcu Belen, Meltem Polat, Christine Bole‐Feysot, Francina Langa‐Vives, Pierre‐Emmanuel Gleizes, Jean‐Pierre deVillartay, Isabelle Callebaut, Anabelle Decottignies, Patrick Revy

“…Using cells from two unrelated HH individuals carrying novel PARN mutations and a human PARN knock‐out (KO) cell line with inducible PARN complementation, we found that PARN deficiency affects both telomere length and stability and down‐regulates the expression of TRF1, TRF2, TPP1, RAP1, and POT1 shelterin transcripts. …”
Get full text

Genome editing-mediated knock-in of therapeutic genes ameliorates the disease phenotype in a model of hemophilia by Jeong Hyeon Lee, Hye-Kyung Oh, Beom Seok Choi, Ho Hyeon Lee, Kyu Jun Lee, Un Gi Kim, Jina Lee, Hyerim Lee, Geon Seong Lee, Se Jun Ahn, Jeong Pil Han, Seokjoong Kim, Su Cheong Yeom, Dong Woo Song

Subjects: Get full text