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    Disease progression strikingly differs in research and real-world Parkinson’s populations by Brett K. Beaulieu-Jones, Francesca Frau, Sylvie Bozzi, Karen J. Chandross, M. Judith Peterschmitt, Caroline Cohen, Catherine Coulovrat, Dinesh Kumar, Mark J. Kruger, Scott L. Lipnick, Lane Fitzsimmons, Isaac S. Kohane, Clemens R. Scherzer

    Published 2024-03-01
    “…The research populations are the Harvard Biomarkers Study (HBS, N = 935), a longitudinal biomarkers cohort study with in-person structured study visits; and Fox Insights (N = 36,660), an online self-survey-based research study of the Michael J. Fox Foundation. Real-world cohorts are the Optum Integrated Claims-electronic health records (N = 157,475), representing wide-scale linked medical and claims data and de-identified data from Mass General Brigham (MGB, N = 22,949), an academic hospital system. …”
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