Precision therapy in pancreatic cancer: from streamlet towards mainstream by LUO Guopei, YU Xianjun

“…In 2019, The New England Journal of Medicine published the POLO study which investigated olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), in patients with metastatic pancreatic cancer and BRCA1 or BRCA2 germline mutation. …”
Get full text

LINFOMA DA ZONA MARGINAL NODAL ASSOCIADO A ANEMIA APLÁSTICA: RELATO DE CASO by RC Bressa, VG Freitas, JAN Bressa

“…Materiais e métodos: Levantamento de prontuário, descrição e discussão de relato de caso com revisão bibliográfica em bancos de dados (BVS/MS, Cochrane, PubMed, The New England Journal of Medicine, e JAMA). Resultados: Paciente, feminina, 56 anos, procura serviço médico ambulatorial com queixa de fraqueza há 6 meses e pancitopenia. …”
Get full text

A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent by Colleen E. Lawrence, Leah Dunkel, Mark McEver, Tiffany Israel, Robert Taylor, Germán Chiriboga, Karin Valentine Goins, Elizabeth J. Rahn, Amy S. Mudano, Erik D. Roberson, Carol Chambless, Virginia G. Wadley, Maria I. Danila, Melissa A. Fischer, Yvonne Joosten, Kenneth G. Saag, Jeroan J. Allison, Stephenie C. Lemon, Paul A. Harris

“…AbstractIntroduction:The updated common rule, for human subjects research, requires that consents “begin with a ‘concise and focused’ presentation of the key information that will most likely help someone make a decision about whether to participate in a study” (Menikoff, Kaneshiro, Pritchard. The New England Journal of Medicine. 2017; 376(7): 613–615.). We utilized a community-engaged technology development approach to inform feature options within the REDCap software platform centered around collection and storage of electronic consent (eConsent) to address issues of transparency, clinical trial efficiency, and regulatory compliance for informed consent (Harris, et al. …”
Get full text

Role of Checkpoint Inhibitors in the Management of Gastroesophageal Cancers by Frederic Karim, Adina Amin, Marie Liu, Nivetha Vishnuvardhan, Saif Amin, Raffey Shabbir, Brandon Swed, Uqba Khan

“…Electronic database (PubMed, Clinicaltrials.gov, Society of Immunotherapy of Cancer, Aliment Pharmacology & Therapeutics, BMC cancer, Molecular Cancer Research, Nature Reviews Molecular Cell Biology, American Association for Cancer Research, Science, Nature, Cancer Discovery, Journal of the National Cancer Institute, Advanced Immunology, Oncotarget, Nature Medicine, Nature Genetics, Gut, Pathology and Oncology Research, Journal of Clinical Oncology, The New England Journal of Medicine, Gastrointestinal oncology, JAMA Oncology, Journal of Gastrointestinal Oncology, Current Oncology, Annals of Oncology, The Lancet, JCO Oncology Practice, Future Oncology, Gastric Cancer, CA: A Cancer Journal for Clinicians, American Journal of Gastroenterology, Gastroenterology, Journal of the National Cancer Institute, International Journal of Epidemiology, Helicobacter, Gastroenterology Review) were searched using a combination of relevant keywords and MESH terms. …”
Get full text

DOSTARLIMAB: A BEACON OF HOPE FOR CANCER PATIENTS by Abdul Haseeb Sahibzada, Fatima Ihsan

“…Anti PD-1 monoclonal antibodies blocks ligand binding to PD-1 and hence reactivates the T cells to act against the tumours.6 A breakthrough in the treatment of cancer and specifically rectal cancer was highlighted recently in a study published in the ‘The new England Journal of Medicine’ the results of phase 2 trial demonstrated that Dostarlimab, an anti-PD-1 monoclonal antibody had shown a 100% clinical complete response rate among a small cohort of patients with mismatch repair-deficient locally advanced rectal cancer. …”
Get full text

Top 100 Cited Articles on Clinical Hematopoietic Stem Cell Transplantation: A Bibliometric Analysis by Moazzam Shahzad, Moazzam Shahzad, Sibgha Gull Chaudhary, Iqra Anwar, Muhammad Arslan, Zehra Naseem, Naira T. Fatima, Sakina Abbas, Tayyaba Ali, Raheel S. Siddiqui, Peiman Hematti, Sunil H. Abhyankar, Joseph P. McGuirk, Muhammad Umair Mushtaq

“…Blood (n = 32) and New England Journal of Medicine (n = 31) made the greatest contribution, and 52 manuscripts were clinical trials. …”
Get full text

Rethinking Figurative Language in the Rhetoric of Healthcare Allocation by Brian Li, Marta Napiorkowska

“… [5] Rashi Fein, “What Is Wrong with the Language of Medicine?,” The New England Journal of Medicine, 1982, https://doi.org/10.1056/NEJM198204083061409…”
Get full text

Fentanyl Overdoses in North America by Matt Dias

“…Califf, Janet Woodcock, and Stephen Ostroff, “A Proactive Response to Prescription Opioid Abuse,” The New England Journal of Medicine 2016; 15(374): 1480–1485, doi: 10.1056/NEJMsr1601307.…”
Get full text

Analysis of Health-Related Quality of Life Reporting in Phase III RCTs of Advanced Genitourinary Tumors by Fabrizio Di Costanzo, Fabiana Napolitano, Fabio Salomone, Anna Rita Amato, Gennaro Alberico, Fortuna Migliaccio, Giovanna Pecoraro, Annachiara Marra, Felice Crocetto, Antonio Ruffo, Sarah Scagliarini, Sabrina Rossetti, Livio Puglia, Marilena Di Napoli, Roberto Bianco, Alberto Servetto, Luigi Formisano

“…Methods: We searched PubMed RCTs testing novel therapies in genitourinary (GU) cancers and published in fifteen selected journals (Annals of Oncology, BMC Cancer, British Journal of Cancer, Cancer Discovery, Clinical Cancer Research, Clinical Genitourinary cancer, European Journal of Cancer, European Urology, European Urology Oncology, JAMA, JAMA Oncology, Journal of clinical Oncology, Lancet, Lancet Oncology and The New England Journal of Medicine). We excluded trials investigating exclusively best supportive care or behavioral intervention, as well as subgroup or post hoc analyses of previously published trials. …”
Get full text

The effects of the menstrual cycle on the physiological responses to exercise in eumenorrheic women at high-altitude by Guia Tagliapietra, Tom Citherlet, Antoine Raberin, Giorgio Manferdelli, Bastien Krumm, Benjamin J. Narang, Nicolas Bourdillon, Tadej Debevec, Guido Giardini, Grégoire Millet

“…Acute high-altitude illnesses. New England Journal of Medicine, 368, 2294–2302. https://doi.org/10.1056/NEJMcp1214870 Burtscher, J., Raberin, A., Brocherie, F., Malatesta, D., Manferdelli, G., Citherlet, T., Krumm, B., Bourdillon, N., Antero, J., Rasica, L., Burtscher, M. & Millet, G. …”
Get full text

In It Together by Silvia Croydon

“…“After the Storm–A Responsible Path for Genome Editing,” New England Journal of Medicine 380, no. 10 (2019): 897-9. doi:10.1056/NEJMp1900504…”
Get full text

Oscilometría de impulso. Una alternativa a la espirometría en enfermedades de vías aéreas pequeñas by H L Ocaña- Servín, A Hardy-Pérez, M E Arceo Guzmán, J Jaimes García, V E Trujillo-Condes, H U López-Díaz

“…Material y métodos: Se buscaron revisiones sistemáticas, metaanálisis y ensayos clínicos de las revistas New England Journal of Medicine, Lancet, Science, Journal of Apply Physiology, Crit Care Med, Chest, Lung, Thorax, Journal of Pediatrics, American Journal of Respiratory and Critical Care Medicine, y revistas latinoamericanas como la Revista de Neumología y Cirugía de Tórax, la Revista de Sanidad Militar, la Revista Colombiana de Neumología, utilizando las bases de datos de Pubmed, Medline, SciELO y www.mdconsult.com. …”
Get full text

Busca por modelos de organização do trabalho nos atendimentos primários de saúde do Brasil e de países internacionais no enfrentamento da Covid-19 by Wellington Pereira Lopes, Ludmila Ichioka, Viviane Micheli Amaral, Glilciane Morceli, Marselle Nobre Carvalho

“…Um novo coronavírus de paciente com pneumonia na China em 2019. The New England Journal of medicine. Disponível em: https://www.nejm.org/doi/full/10.1056/nejmoa2001017, acessado dia 04/06/2020…”
Get full text

Ventilación líquida. Metaanálisis y revisión sistemática de la literatura by J. Mariol Palacios Lara, B X Pasco Ramírez, H L Ocaña Servín, M E Arceo Gúzman, A E Hardy Pérez, J Jaimes García, H U López Díaz, M L Palacios Jaimes, M Hernández Sánchez

“…Analizando lo que dice la literatura y cómo ha funcionado en pacientes con Covid-19 y sira que ameritaron internamiento en unidades de cuidados intensivos.Material y métodos: Se buscaron revisiones sistemáticas, metaa-nálisis y ensayos clínicos de las revistas The New England Journal of Medicine, The Lancet , Science, Journal of Apply Physiology, Crit Care Med, Chest, Lung, Journal of Pediatrics, American Journal of Respiratory and Critical Care Medicine, Medicina Intensiva, Revista de la Facultad de Medicina de la UNAM, utilizando las bases de datos de Pubmed, medline, y www.mdconsult.com. …”
Get full text

Truth and Transparency, Compromise and Climate Change by Jose Florencio Lapeña

“…On another front, the Philippine Journal of Otolaryngology Head and Neck Surgery has agreed to co-publish an editorial calling on wealthy countries to do more to support Africa and other vulnerable nations in mitigating the impact of climate change on health.8  The guest editorial in this issue is authored by the editors of 16 African health journals, and is co-published by 259 international journals, including The Lancet, British Medical Journal, New England Journal of Medicine, National Medical Journal of India, and Medical Journal of Australia and the Philippine Journal of Otolaryngology Head and Neck Surgery (see http://press.psprings.co.uk/bmj/october/Journals.pdf). …”
Get full text

Global trends in the health economics field of PD-1/PD-L1 inhibitors: A bibliometric and visualized study by Sicen Lai, Sicen Lai, Sicen Lai, Sicen Lai, Licong Xu, Licong Xu, Licong Xu, Licong Xu, Liang Zhang, Lanyuan Peng, Lanyuan Peng, Lanyuan Peng, Lanyuan Peng, Yixin Li, Yixin Li, Yixin Li, Yixin Li, Yuancheng Liu, Yuancheng Liu, Yuancheng Liu, Yuancheng Liu, Nianzhou Yu, Nianzhou Yu, Nianzhou Yu, Nianzhou Yu, Wangqing Chen, Wangqing Chen, Wangqing Chen, Wangqing Chen, Kai Huang, Kai Huang, Kai Huang, Kai Huang

“…Value in Health (166 publications, 13.79% of total documents) had the most publications, while New England Journal of Medicine (2,890 co-citations) was the most co-cited journal. …”
Get full text

Reducing the Risks of Nuclear War— the Role of Health Professionals by Kamran Abbasi, Parveen Ali, Virginia Barbour, Kirsten Bibbins-Domingo, Marcel GM Olde Rikkert, Andy Haines, Ira Helfand, Richard Horton, Robert Mash, Arun Mitra, Carlos Monteiro, Elena Naumova, Eric Rubin, Tilman Ruff, Peush Sahni, James Tumwine, Paul Yonga Yonga, Chris Zielinski

Get full text

The Quest for Ethical Isometric Principles in Cross-Cultural Bioethical Research by Emmanuel Kornyo

“…"Ethical and Scientific Implications of the Globalization of Clinical Research." New England Journal of Medicine 360, no. 8 (2009): 816-23. See also, Arun Bhatt “Quality of Clinical Trials: A moving Target in Perspectives” Clinical Research. …”
Get full text

Effects of age on hypoxic tolerance in women by Tom Citherlet, Antoine Raberin, Giorgio Manferdelli, Grégoire Millet

“…Acute high-altitude illnesses. New England Journal of Medicine, 368(24), 2294-2302. https://doi.org/10.1056/NEJMcp1214870 Kronenberg, R. …”
Get full text

Confidentiality and Cost by Kaitlynd Hiller

“… [2] Brooke Winner, et al., “Effectiveness of Long-Acting Reversible Contraception,” New England Journal of Medicine 366 (2012). Page numbers? [3] “Unintended Pregnancy in the United States,” Guttmacher Institute, accessed October 14, 2014, http://www.guttmacher.org/pubs/FB-Unintended-Pregnancy-US.html#10…”
Get full text