Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the Open... by Krishnan Bhaskaran, Sebastian Bacon, Stephen JW Evans, Chris J Bates, Christopher T Rentsch, Brian MacKenna, Laurie Tomlinson, Alex J Walker, Anna Schultze, Caroline E Morton, Daniel Grint, Amir Mehrkar, Rosalind M Eggo, Peter Inglesby, Ian J Douglas, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, Helen J Curtis, William J Hulme, John Parry, Frank Hester, Sam Harper, David Spiegelhalter, Liam Smeeth, Ben Goldacre

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Identifying Care Home Residents in Electronic Health Records - An OpenSAFELY Short Data Report [version 1; peer review: 2 approved] by Anna Schultze, Chris Bates, Jonathan Cockburn, Brian MacKenna, Emily Nightingale, Helen J Curtis, William J Hulme, Caroline E Morton, Richard Croker, Seb Bacon, Helen I McDonald, Christopher T Rentsch, Krishnan Bhaskaran, Rohini Mathur, Laurie A Tomlinson, Elizabeth J Williamson, Harriet Forbes, John Tazare, Daniel J Grint, Alex J Walker, Peter Inglesby, Nicholas J DeVito, Amir Mehrkar, George Hickman, Simon Davy, Tom Ward, Louis Fisher, David Evans, Kevin Wing, Angel YS Wong, Robert McManus, John Parry, Frank Hester, Sam Harper, Stephen JW Evans, Ian J Douglas, Liam Smeeth, Rosalind M Eggo, Ben Goldacre

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Utilising primary care electronic health records to deliver the ALABAMA randomised controlled trial of penicillin allergy assessment by Shadia Ahmed, Joanne Fielding, Catherine E. Porter, Kelsey F. Armitage, Marta Wanat, Chris Bates, Lazarina Engonidou, Robert M. West, Ly-Mee Yu, Ushma Galal, Philip Howard, Christopher C. Butler, Sinisa Savic, Jenny Boards, Sarah Tonkin-Crine, John Parry, Sue A. Pavitt, Jonathan T. Sandoe, on behalf of ALABAMA research team

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Estimating primary care attendance rates for fever in infants after meningococcal B vaccination in England using national syndromic surveillance data by Harcourt, S, Morbey, RA, Bates, C, Carter, H, Ladhani, SN, de Lusignan, S, Smith, GE, Elliot, AJ

“…<p><strong>Methods</strong></p> Consultations for infant all-cause fever in the year following the vaccine introduction were identified from The Phoenix Partnership (TPP) ResearchOne general practice database using Read (CTV3) codes. …”

Evaluation of the impact of COVID-19 pandemic on hospital admission related to common infections: Risk prediction models to tackle antimicrobial resistance in primary care. by Ali Fahmi, Victoria Palin, Xiaomin Zhong, Ya-Ting Yang, Simon Watts, Darren M Ashcroft, Ben Goldacre, Brian MacKenna, Louis Fisher, Jon Massey, Amir Mehrkar, Seb Bacon, OpenSAFELY Collaborative, Kieran Hand, Tjeerd Pieter van Staa

“…<h4>Methods</h4>With the approval of NHS England, we accessed electronic health records from The Phoenix Partnership (TPP) through OpenSAFELY platform. We included adult patients with primary care diagnosis of common infections, including lower respiratory tract infection (LRTI), upper respiratory tract infections (URTI), and lower urinary tract infection (UTI), from 1 January 2019 to 31 August 2022. …”
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Evaluation of the impact of COVID-19 pandemic on hospital admission related to common infections: Risk prediction models to tackle antimicrobial resistance in primary care by Fahmi, A, Palin, V, Zhong, X, Yang, Y, Watts, S, Ashcroft, DM, Goldacre, B, MacKenna, B, Fisher, L, Massey, J, Mehrkar, A, Bacon, S, the OpenSAFELY Collaborative, Hand, K, van Staa, TP

“…Methods: With the approval of NHS England, we accessed electronic health records from The Phoenix Partnership (TPP) through OpenSAFELY platform. We included adult patients with primary care diagnosis of common infections, including lower respiratory tract infection (LRTI), upper respiratory tract infections (URTI), and lower urinary tract infection (UTI), from 1 January 2019 to 31 August 2022. …”

Predicting incident heart failure from population-based nationwide electronic health records: protocol for a model development and validation study by Chris Gale, Ahmet Fuat, Jianhua Wu, Ramesh Nadarajah, Farag Shuweihdi, Yoko M Nakao, Christopher Bates, Kazuhiro Nakao, Jim Moore

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Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and econ... by Michael Marks, Mark Jit, Frank Sandmann, Ben Goldacre, Liam Smeeth, Laurie A Tomlinson, Liang-Yu Lin, Emily Herrett, Deb Smith, Jessica Morley, Andrew Briggs, Seb Bacon, Amir Mehrkar, John Parry, Keith Tomlin, Viyaasan Mahalingasivam, Christopher Bates, Benjamin Butler-Cole, Alan Dennison, Ethan Gabriel, Rosalind M M Eggo

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Liaison psychiatry—measurement and evaluation of service types, referral patterns and outcomes (LP-MAESTRO): a protocol by Chris Smith, Allan House, Elspeth Guthrie, Carolyn J Czoski Murray, Jenny Hewison, Robert M West, Claire Hulme, Peter Trigwell, Mike J Crawford, Matt Fossey, Sandy Tubeuf

“…Introduction We describe the protocol for a project that will use linkage of routinely collected NHS data to answer a question about the nature and effectiveness of liaison psychiatry services in acute hospitals in England.Methods and analysis The project will use three data sources: (1) Hospital Episode Statistics (HES), a database controlled by NHS Digital that contains patient data relating to emergency department (ED), inpatient and outpatient episodes at hospitals in England; (2) ResearchOne, a research database controlled by The Phoenix Partnership (TPP) that contains patient data relating to primary care provided by organisations using the SystmOne clinical information system and (3) clinical databases controlled by mental health trusts that contain patient data relating to care provided by liaison psychiatry services. …”
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Connected Bradford:  a Whole System Data Linkage Accelerator [version 2; peer review: 2 approved] by Dan Mason, John Wright, Kuldeep Sohal, Mai Elshehaly, Mark Mon-Williams, John Birkinshaw, Megan Wood, Rob Shore, Chris Bates, Michael McCooe, Tom Lawton, Rosemary R.C. McEachan, Duncan Cooper, Trevor Sheldon, Jane West

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Towards UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): protocol for an evaluation of the requirements for arthroplasty follow-up, and the production of consensus-based r... by Andrew Judge, Sarah R Kingsbury, Nigel K Arden, Jamie Matu, Jamie O’Shea, Rafael Pinedo-Villanueva, Lindsay K Smith, Christine M Thomas, Robert M West, Martin H Stone

“…Following advice from the Confidentiality Advisory Group (17/CAG/0122), data controllers for the data sets used in WP2a (RO-HES) – NHS Digital and The Phoenix Partnership – confirmed that Section 251 support was not required as no identifiable data was flowing into or out of these parties. …”
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The Use of Online Consultation Systems or Remote Consulting in England Characterized Through the Primary Care Health Records of 53 Million People in the OpenSAFELY Platform: Retros... by Martina Fonseca, Brian MacKenna, Amir Mehrkar, Caroline E Walters, George Hickman, Jonathan Pearson, Louis Fisher, Peter Inglesby, Seb Bacon, Simon Davy, William Hulme, Ben Goldacre, Ofra Koffman, Minal Bakhai

“…MethodsWith the approval of NHS England, the OpenSAFELY platform was used to query and analyze the in situ electronic health records of suppliers The Phoenix Partnership (TPP) and Egton Medical Information Systems, covering >53 million patients in >6400 practices, mainly in 2019-2020. …”
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Linkage of routinely collected NHS data to evaluate liaison mental health services: challenges and lessons learned by Elspeth Guthrie, Allan House, Chris Smith, Sam Relton, Daniel Romeu, Sonia Saraiva, Peter Trigwell, Robert West, Farag Shuweihdi, Mike Crawford, Matt Fossey, Jenny Hewison, Claire Hulme, Sandy Tubeuf

“…We designed and enacted a methodology to link data from: (1) Hospital Episode Statistics, a database controlled by the National Health Service Digital and (2) ResearchOne, a primary care database controlled by The Phoenix Partnership. Results Obtaining approvals for the steps prespecified in the methodological protocol took 907 days. …”
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Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP by Andrew Steptoe, John Macleod, Daniel McCartney, Aziz Sheikh, Annie Herbert, Ben Goldacre, David Evans, Louise Jones, Sam Harper, Michael Green, Nicholas Timpson, John Wright, Liam Smeeth, Laurie A Tomlinson, Sinead Brophy, Kate Tilling, Andy Gibson, Paola Zaninotto, Stefan Neubauer, Yinghui Wei, Betty Raman, Chloe Park, Alun Hughes, Jonathan Sterne, Elena Lukaschuk, Stefan Piechnik, Angela Wood, Mark Green, Agnieszka Lemanska, Krishnan Bhaskaran, Kathryn Willan, Elsie Horne, Hannah Woodward, Ian Douglas, Andrew Wong, Andy Boyd, Harriet Forbes, Sinéad Langan, Nishi Chaturvedi, Tom Palmer, Kathryn Mansfield, Rachel Denholm, Emily Herrett, Kevin Wang, Bo Hou, Felix Greaves, Laura Sheard, Praveetha Patalay, Kishan Patel, Jessica Morley, Bang Zheng, Charlotte Booth, Spiros Denaxas, Brian MacKenna, Ruth E Costello, Jonathan Kennedy, William Hulme, Michael Parker, Geneviève Cezard, Syed A Shah, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, Laurie Tomlinson, John Parry, Frank Hester, Eoin McElroy, Amelia Green, Gillian Santorelli, Alisia Carnemolla, Richard Shaw, Samantha Ip, Venexia Walker, Emma L Turner, Richard Thomas, Rebecca Rhead, Archie Campbell, Ellen Thompson, Ruth Bowyer, Jane Maddock, Helen Curtis, Alex Walker, Olivia Hamilton, Rosie McEachan, Ellena Badrick, Stephen Smith, Richard Dobson, Stela McLachlan, Vanessa Ferreira, Vittal Katikireddi, Scott Walker, Lucy Teece, Simon Davy, John Tazare, Bettina Moltrecht, Theocharis Kromydas, Giorgio Di Gessa, Gareth Griffith, Viyaasan Mahalingasivam, Elizabeth Tunnicliffe, George Hickman, Tom Ward, Rebecca M Smith, Sam Parsons, Callum Stewart, Amos Folarin, Daniel Kopasker, Claire Steves, Louis Fisher, Sebastian C J Bacon, Lisa Hopcroft, Robin Y Park, Jon Massey, Iain Dillingham, Steven Maude, Wels Jacques, Linda Nab, Christopher Bates, Milan Wiedemann, Ruth Mitchell, Chao Fang, Fatima Almaghrabi, Jingmin Zhu, Lucy Bridges, Kurt Taylor, Colm Andrews, Jean Stafford, Nathan Cheetham, Sebastian CJ Bacon, Alicja Rapala, Robin Flaig, Andrea L Schaffer, Benjamin FC Butler-Cole, Liam Hart Ben Goldacre, Thomas O’Dwyer, Dylan Williams, Anika Knueppel, Katharine M Evans, Samantha Berman, Matthew Crane, Rebecca Whitehorn, Jacqui Oakley, Diane Foster, Kirsteen C Campbell, Alex Kwong, Ana Goncalves Soares, Renin Toms, Lizzie Huntley, Laura Fox, Rochelle Knight, Northstone Kate, Kanagaratnam Arun, Teri North, Marwa AL Arab, Jose IC Coronado, Arun S Karthikeyan, Ploubidis George, Bozena Wielgoszewska, Charis Bridger-Staatz, Paz Garcia, Maxim Freydin, Amy Roberts, Alex Walker Ben Goldacre, Jess Morley, Anoop Shah Richard Silverwood, Thomas Cowling, Kate Mansfield, Tiffany Yang, Tom Bolton, Alexia Sampri, Elena Rafeti, Robert Willans, Fiona Glen, Steve Sharp, Lee Hamill Howes, Lidia Nigrelli, Fintan McArdle, Chelsea Beckford, Yatharth Ranjan, Jd Carpentieri, Sarah Baz, John Kellas, Laura C Saunders, James M Wild, Peter Jezzard, Zeena-Britt Sanders, Lucy Finnigan, Milla Kibble, Francisco Perez-Reche, Dominik Piehlmaier, Edward Parker

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