811 Transient EZH2 suppression by tazemetostat during in vitro expansion maintains T cell stemness and improves adoptive T cell therapy by Peng Wu, Yingqin Hou

Role of metallothionein-III following central nervous system damage by Javier Carrasco, Milena Penkowa, Mercedes Giralt, Jordi Camats, Amalia Molinero, Iain L. Campbell, Richard D. Palmiter, Juan Hidalgo

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An Alternative Terminal Step of the General Secretory Pathway in <named-content content-type="genus-species">Staphylococcus aureus</named-content> by Arryn Craney, Melissa M. Dix, Ramkrishna Adhikary, Benjamin F. Cravatt, Floyd E. Romesberg

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Optical quantification of cellular mass, volume and density of circulating tumor cells identified in an ovarian cancer patient by Kevin Gregory Phillips, Carmen Ruiz Velasco, Julia eLi, Anand eKolatkar, Madelyn eLuttgen, Kelly eBethel, Bridgette eDuggan, Peter eKuhn, Owen eMcCarty

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Activation of Pro-uPA Is Critical for Initial Escape from the Primary Tumor and Hematogenous Dissemination of Human Carcinoma Cells by Erin M. Bekes, Elena I. Deryugina, Tatyana A. Kupriyanova, Ewa Zajac, Kenneth A. Botkjaer, Peter A. Andreasen, James P. Quigley

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LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors by Ignacio Sarria, Yan Cao, Yuchen Wang, Norianne T. Ingram, Cesare Orlandi, Naomi Kamasawa, Alexander V. Kolesnikov, Johan Pahlberg, Vladimir J. Kefalov, Alapakkam P. Sampath, Kirill A. Martemyanov

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Combined accelerometer and genetic analysis to differentiate essential tremor from Parkinson’s disease by Bhuvan Molparia, Brian N. Schrader, Eli Cohen, Jennifer L. Wagner, Sandeep R. Gupta, Sherrie Gould, Nelson Hwynn, Emily G. Spencer, Ali Torkamani

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And then there were two by Lorraine F Clark, Thomas Kodadek

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Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2 by Maya L Bulos, Edyta M Grzelak, Chloris Li-Ma, Emily Chen, Mitchell Hull, Kristen A Johnson, Michael J Bollong

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Structural features of synthetic peptides of apolipoprotein E that bind the LDL receptor by C A Dyer, D P Cistola, G C Parry, L K Curtiss

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Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists by Linda K. Curtiss, Audrey S. Black, David J. Bonnet, Peter S. Tobias

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Central nervous system (CNS) transcriptomic correlates of human immunodeficiency virus (HIV) brain RNA load in HIV-infected individuals by Pietro Paolo Sanna, Yu Fu, Eliezer Masliah, Celine Lefebvre, Vez Repunte-Canonigo

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Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency by David T. Valenta, Joshua J. Bulgrien, David J. Bonnet, Linda K. Curtiss

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Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice by Nobuhiko Kubo, William A. Boisvert, Christie M. Ballantyne, Linda K. Curtiss

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Lead identification using 3D models of pancreatic cancer by Virneliz Fernandez-Vega, Shurong Hou, Dennis Plenker, Hervé Tiriac, Pierre Baillargeon, Justin Shumate, Louis Scampavia, Jan Seldin, Glauco R. Souza, David A. Tuveson, Timothy P. Spicer

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Prefrontal cortex glutamatergic adaptations in a mouse model of alcohol use disorder by Mahum T. Siddiqi, Dhruba Podder, Amanda R. Pahng, Alexandria C. Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J. Roberts, Scott Edwards, Marisa Roberto, Florence P. Varodayan

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A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin by Eirini Vamva, Stosh Ozog, Daniel P. Leaman, Rene Yu-Hong Cheng, Nicholas J. Irons, Andee Ott, Claire Stoffers, Iram Khan, Geraldine K.E. Goebrecht, Matthew R. Gardner, Michael Farzan, David J. Rawlings, Michael B. Zwick, Richard G. James, Bruce E. Torbett

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Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging by Andria R. Robinson, Matthew J. Yousefzadeh, Tania A. Rozgaja, Jin Wang, Xuesen Li, Jeremy S. Tilstra, Chelsea H. Feldman, Siobhán Q. Gregg, Caroline H. Johnson, Erin M. Skoda, Marie-Céline Frantz, Harris Bell-Temin, Hannah Pope-Varsalona, Aditi U. Gurkar, Luigi A. Nasto, Renã A.S. Robinson, Heike Fuhrmann-Stroissnigg, Jolanta Czerwinska, Sara J. McGowan, Nadiezhda Cantu-Medellin, Jamie B. Harris, Salony Maniar, Mark A. Ross, Christy E. Trussoni, Nicholas F. LaRusso, Eugenia Cifuentes-Pagano, Patrick J. Pagano, Barbara Tudek, Nam V. Vo, Lora H. Rigatti, Patricia L. Opresko, Donna B. Stolz, Simon C. Watkins, Christin E. Burd, Claudette M. St. Croix, Gary Siuzdak, Nathan A. Yates, Paul D. Robbins, Yinsheng Wang, Peter Wipf, Eric E. Kelley, Laura J. Niedernhofer

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Integrative modeling of JCVI-Syn3A nucleoids with a modular approach by David S. Goodsell, Ludovic Autin

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PP 2.7 – 00093 Modeling HIV-1 Pathogenesis and Latency in iPSC-Derived Human Cerebral Organoids by J. Crater, T. Premeaux, A. Leda, S. Jablonski, K. Newcombe, H. Fine, S. Valente, L. Ndhlovu, R. Furler O'Brien, D. Nixon

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