An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar by Nathan D. Grubaugh, Karthik Gangavarapu, Joshua Quick, Nathaniel L. Matteson, Jaqueline Goes De Jesus, Bradley J. Main, Amanda L. Tan, Lauren M. Paul, Doug E. Brackney, Saran Grewal, Nikos Gurfield, Koen K. A. Van Rompay, Sharon Isern, Scott F. Michael, Lark L. Coffey, Nicholas J. Loman, Kristian G. Andersen

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Pα-syn* mitotoxicity is linked to MAPK activation and involves tau phosphorylation and aggregation at the mitochondria by Diego Grassi, Natalia Diaz-Perez, Laura A. Volpicelli-Daley, Corinne Ida Lasmézas

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Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patie... by Kevin Gregory Phillips, Anand eKolatkar, Kathleen J. Rees, Rachel eRigg, Dena eMarrinucci, Madelyn eLuttgen, Kelly eBethel, Peter eKuhn, Peter eKuhn, Owen J.T. McCarty

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Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate by Franck Madoux, Daniela Dreymuller, Jean-Phillipe Pettiloud, Radleigh Santos, Christoph Becker-Pauly, Andreas Ludwig, Gregg B. Fields, Thomas Bannister, Timothy P. Spicer, Mare Cudic, Louis D. Scampavia, Dmitriy Minond

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Origin and Lineage Plasticity of Endogenous Lacrimal Gland Epithelial Stem/Progenitor Cells by Liana Basova, Geraint J. Parfitt, Alex Richardson, Vanessa Delcroix, Takeshi Umazume, Daniel Pelaez, David T. Tse, Ivo Kalajzic, Nick Di Girolamo, James V. Jester, Helen P. Makarenkova

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Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework by Simon Dellicour, Sebastian Lequime, Bram Vrancken, Mandev S. Gill, Paul Bastide, Karthik Gangavarapu, Nathaniel L. Matteson, Yi Tan, Louis du Plessis, Alexander A. Fisher, Martha I. Nelson, Marius Gilbert, Marc A. Suchard, Kristian G. Andersen, Nathan D. Grubaugh, Oliver G. Pybus, Philippe Lemey

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Phenotypic changes in the brain of SIV-infected macaques exposed to methamphetamine parallel macrophage activation patterns induced by the common gamma-chain cytokine system by Nikki eBortell, Brenda eMorsey, Liana eBasova, Howard S Fox, Maria Cecilia G Marcondes

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Control of stilbene conformation and fluorescence in self-assembled capsules by Mark R. Ams, Dariush Ajami, Stephen L. Craig, Jye-Shane Yang, Julius Rebek Jr

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The Cyclophilin Inhibitor Rencofilstat Decreases HCV-Induced Hepatocellular Carcinoma Independently of Its Antiviral Activity by Winston Stauffer, Michael Bobardt, Daren Ure, Robert Foster, Philippe Gallay

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LPA receptor signaling: pharmacology, physiology, and pathophysiology by Yun C. Yung, Nicole C. Stoddard, Jerold Chun

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Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels by Sebok K. Halder, Ravi Kant, Richard Milner

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Inhibition of autophagic flux by S-nitrosylation of SQSTM1/p62 promotes neuronal secretion and cell-to-cell transmission of SNCA/α-synuclein in Parkinson disease and Lewy body deme... by Chang-ki Oh, Tomohiro Nakamura, Stuart A. Lipton

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Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells by Guocai Zhong, Haimin Wang, Charles C Bailey, Guangping Gao, Michael Farzan

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Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases by Dorit Trudler, Swagata Ghatak, Stuart A. Lipton

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A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia by Layne N. Rodden, Christian Rummey, Yi Na Dong, Sarah Lagedrost, Sean Regner, Alicia Brocht, Khalaf Bushara, Martin B. Delatycki, Christopher M. Gomez, Katherine Mathews, Sarah Murray, Susan Perlman, Bernard Ravina, S. H. Subramony, George Wilmot, Theresa Zesiewicz, Alessandra Bolotta, Alain Domissy, Christine Jespersen, Baohu Ji, Elisabetta Soragni, Joel M. Gottesfeld, David R. Lynch

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Targeting the Orexin System for Prescription Opioid Use Disorder by Alessandra Matzeu, Rémi Martin-Fardon

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P1303: POTENTIATING ANTI-CD20 MONOCLONAL ANTIBODY THERAPY BY TARGETING COMPLEMENT C3 ACTIVATION FRAGMENTS COVALENTLY DEPOSITED ON LYMPHOMA CELLS by A. Wiestner, S. Baskar, H. Peng, E. Gaglione, M. Lindorfer, R. Taylor, C. Rader

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Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats by Valentina Vozella, Bryan Cruz, Luis A. Natividad, Federica Benvenuti, Nazzareno Cannella, Scott Edwards, Eric P. Zorrilla, Roberto Ciccocioppo, Marisa Roberto

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Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors by Cesare Orlandi, Yoshihiro Omori, Yuchen Wang, Yan Cao, Akiko Ueno, Michel J. Roux, Giuseppe Condomitti, Joris de Wit, Motoi Kanagawa, Takahisa Furukawa, Kirill A. Martemyanov

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Chemical activation of the mechanotransduction channel Piezo1 by Ruhma Syeda, Jie Xu, Adrienne E Dubin, Bertrand Coste, Jayanti Mathur, Truc Huynh, Jason Matzen, Jianmin Lao, David C Tully, Ingo H Engels, H Michael Petrassi, Andrew M Schumacher, Mauricio Montal, Michael Bandell, Ardem Patapoutian

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