Immune correlates of therapy outcomes in women with cervical cancer treated with chemoradiotherapy: A systematic review by David S. Lakomy, Juliana Wu, Dorothy Lombe, Emmanouil Papasavvas, Susan Citonje Msadabwe, Yimin Geng, Luis J. Montaner, Elizabeth Chiao, Lilie L. Lin

Get full text

Immune Responses of a Novel Bi-Cistronic SARS-CoV-2 DNA Vaccine Following Intradermal Immunization With Suction Delivery by Moonsup Jeong, Sagar B. Kudchodkar, Areum Gil, Bohyun Jeon, Gee Ho Park, Youngran Cho, Hyojin Lee, Mi Sun Cheong, Wonil Kim, Yun-Ho Hwang, Jung-Ah Lee, Heeji Lim, Mi Young Kim, Emran O. Lallow, Tej Brahmbhatt, Stephen A. Kania, Nandita C. Jhumur, Jerry W. Shan, Jeffrey D. Zahn, David I. Shreiber, Jonathan P. Singer, Hao Lin, Erin K. Spiegel, Laurent Pessaint, Maciel Porto, Alex Van Ry, Danielle Nase, Swagata Kar, Hanne Andersen, Ian Tietjen, Joel Cassel, Joseph M. Salvino, Luis J. Montaner, Young K. Park, Kar Muthumani, Christine C. Roberts, Joel N. Maslow

Get full text

Editorial: Double-edged swords: Important factors connecting metabolic disorders and cancer development – from basic research to translational applications by Che-Pei Kung, Thibaut Barnoud, Cong-Hui Yao, Maureen E. Murphy

Get full text

Marked variation in the susceptibility of HIV-1 to type 1 interferon inhibition during early, late and rebound infection by M. Gondim, S. Sherrill-Mix, M. Saag, M. Nussenzweig, J. Silicano, P. Sharp, P. Borrow, L. Montaner, K. Bar, B. Hahn

Get full text

Corrigendum: The critical role of PARPs in regulating innate immune responses by Huifang Zhu, Yan-Dong Tang, Guoqing Zhan, Chenhe Su, Chunfu Zheng

Get full text

Editorial: Double-Edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer by Che-Pei Kung, Che-Pei Kung, Maureen E. Murphy, Hua Lu

Get full text

OP 6.4 – 00096 High-efficiency CRISPR/Cas9-mediated disruption of ccr5 in human hematopoietic stem progenitor cells generates HIV-refractory immune systems by D. Claiborne, Z. Detwiler, K. Okawa, T. Bateson, T. Chen, D. Scadden, C. Boutwell, T. Allen

Get full text

Distinct HIV reservoir measures correlate with defective but not intact pro-viral DNA by E. Papasavvas, L. Azzoni, P. Tebas, K. Mounzer, J.R. Kostman, D. Richman, N. Chomont, B. Howell, L.J. Montaner

Get full text

A functionally significant SNP in TP53 and breast cancer risk in African-American women by Maureen E. Murphy, Song Liu, Song Yao, Dezheng Huo, Qin Liu, Sonia C. Dolfi, Kim M. Hirshfield, Chi-Chen Hong, Qiang Hu, Andrew F. Olshan, Temidayo O. Ogundiran, Clement Adebamowo, Susan M. Domchek, Katherine L. Nathanson, Barbara Nemesure, Stefan Ambs, William J. Blot, Ye Feng, Esther M. John, Leslie Bernstein, Wei Zheng, Jennifer J. Hu, Regina G. Ziegler, Sarah Nyante, Sue A. Ingles, Michael F. Press, Sandra L. Deming, Jorge L. Rodriguez-Gil, Christopher A. Haiman, Olufunmilayo I. Olopade, Kathryn L. Lunetta, Julie R. Palmer, Christine B. Ambrosone

“…In a study of more than 14,000 women of African ancestry, a team led by Maureen Murphy from the Wistar Institute in Philadelphia, Pennsylvania, USA, and Christine Ambrosone from Roswell Park Cancer Institute in Buffalo, NY, USA, tested for an association between breast cancer and a rare genetic polymorphism in the TP53 gene that’s found almost exclusively in African-descent populations. …”
Get full text

PP 8.3 – 00049 Reduction in Markers of HIV Persistence with Gag/Pol/Il-12 DNA Therapeutic Vaccination by K. Chew, D. Glidden, R. Fromentin, J. Jacobs, G. Laird, N. Chomont, J. Mellors, D. Weiner, S. Deeks, R. Rutishauser

Get full text

Integrated microRNA–mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism by Pritmohinder S. Gill, Harsh Dweep, Shannon Rose, Priyankara J. Wickramasinghe, Kanan K. Vyas, Sandra McCullough, Patricia A. Porter-Gill, Richard E. Frye

Get full text

A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription by Xuanmao Jiao, Gabriele Di Sante, Mathew C. Casimiro, Agnes Tantos, Anthony W. Ashton, Zhiping Li, Yen Quach, Dharmendra Bhargava, Agnese Di Rocco, Claudia Pupo, Marco Crosariol, Tamas Lazar, Peter Tompa, Chenguang Wang, Zuoren Yu, Zhao Zhang, Kawthar Aldaaysi, Ratna Vadlamudi, Monica Mann, Emmanuel Skordalakes, Andrew Kossenkov, Yanming Du, Richard G. Pestell

Get full text

PP 1.44 – 00107 Longitudinal evaluation of epigenetic age among people living with HIV (PLWH) undergoing multimodal curative interventions by M. Corley, N. Mantovani, L. Giron, A. Pang, J. Galinskas, D. Dias, J. Hunter, A. Savarino, R. Diaz, L. Ndhlovu

Get full text

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow by Arielle Glatman Zaretsky, Christoph Konradt, Fabien Dépis, James B. Wing, Radhika Goenka, Daniela Gomez Atria, Jonathan S. Silver, Sunglim Cho, Amaya I. Wolf, William J. Quinn, Julie B. Engiles, Dorothy C. Brown, Daniel Beiting, Jan Erikson, David Allman, Michael P. Cancro, Shimon Sakaguchi, Li-Fan Lu, Christophe O. Benoist, Christopher A. Hunter

Get full text

LIMD2 Regulates Key Steps of Metastasis Cascade in Papillary Thyroid Cancer Cells via MAPK Crosstalk by Rodrigo Pinheiro Araldi, Thatiana Correa de Melo, Débora Levy, Dener Madeiro de Souza, Beatriz Maurício, Gabriel Avelar Colozza-Gama, Sergio Paulo Bydlowski, Hongzhuang Peng, Frank J. Rauscher, Janete Maria Cerutti

Get full text

Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States by Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé

Get full text

PP 4.8 – 00108 Presentation of cognate antigens by dendritic cells causes stochastic HIV expression by M. Moskovljevic, F. Dragoni, F. Wu, N.L. Board, J. Lai, L.J. Montaner, S.G. Deeks, J.D. Siliciano, R.F. Siliciano, F.R. Simonetti

Get full text

PP 8.4 – 00061 Bispecific antibodies promote natural killer cell-mediated elimination of the HIV reservoir by N. Board, F. Wu, M. Moskovljevic, M. Ravi, S. Sengupta, F. Simonetti, L. Montaner, S. Deeks, J. Siliciano, R. Siliciano

Get full text

Correction to: Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes by Konstantinos Voskarides, Harsh Dweep, Charalambos Chrysostomou

Get full text

Post-therapy viral set-point abatement following combined antiproliferative and immune-boosting interventions: results from a randomised clinical trial by R. Sobhie Diaz, L.B. Giron, J. Galinskas, J. Hunter, M. Janini, I.L. Shytaj, R. Cauda, M.C. Sucupira, J. Maricato, A. Savarino

Get full text