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12361
The Asociación Mexicana de Gastroenterología consensus on the diagnosis and treatment of acute pancreatitis in children and adolescents
Published 2023-07-01“…Different AP topics were addressed by 6 working groups, each of which reviewed the information and formulated statements considered pertinent for each module, on themes involving recommendations and points of debate, concerning diagnostic or therapeutic approaches. All the statements were presented and discussed. …”
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12362
High PD-L1/IDO-2 and PD-L2/IDO-1 Co-Expression Levels Are Associated with Worse Overall Survival in Resected Non-Small Cell Lung Cancer Patients
Published 2021-02-01“…These features may have important implications for future immune-checkpoint therapeutic approaches.…”
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12363
Consenso de la Asociación Mexicana de Gastroenterología sobre el diagnóstico y tratamiento de pancreatitis aguda en niñas, niños y adolescentes
Published 2023-07-01“…Different AP topics were addressed by 6 working groups, each of which reviewed the information and formulated statements considered pertinent for each module, on themes involving recommendations and points of debate, concerning diagnostic or therapeutic approaches. All the statements were presented and discussed. …”
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12364
The Real-World Data in Japanese Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib from a Nationwide Multicenter Study
Published 2021-05-01“…The patients with bone metastasis would be candidates for new therapeutic approaches.…”
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12365
PARP1 IS DIFFERENTIALLY EXPRESSED IN BCR-ABL P190+ ALL PATIENT SAMPLES AND TARGETING PARP INHIBITION INDUCES CELL DEATH COMPARABLE TO THAT OF TYROSINE-KINASE GOLDEN STANDARD IN PRE...
Published 2023-10-01“…Objective: BCR-ABL1 p190 translocation represents a worse prognosis for acute lymphoblastic leukemia (ALL) patients, and development of new therapeutic approaches is of utmost importance to the oncologic routine. …”
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PREDICTIVE FACTORS AND CLINICAL AND PARACLINICAL FEATURES OF URINARY TRACT DYSFUNCTION IN PRETERM INFANTS
Published 2023-10-01“…The research themes included: a research project on ‘Improvement of Prognostic, Diagnostic, and Therapeutic Approaches to Perinatal Pathology in Newborns and Infants, Optimization of Followup and Rehabilitation Schemes’ (State registration number 0115U002768, duration from 01.2015 to 12.2019); and a research project on ‘Chronobiological and Adaptive Aspects, as well as Features of Vegetative Regulation in Pathological Conditions in Children of Diff erent Age Groups’ (State registration number 0122U002245, duration from 01.2020 to 12.2024). …”
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12367
Cellular responses against DNA damaged by platinum anticancer drugs
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12368
Investigating isocitrate dehydrogenase mutations in cancer using new metabolomics methods
Published 2020“…Consequently, there is a need for better diagnostic and therapeutic approaches. Small molecule inhibitors, which are specific to isocitrate dehydrogenase mutations and reduce the abundance of 2 hydroxyglutarate, have been developed; however, resistance to treatment has since been reported, including the manifestation of second site mutations. …”
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Influência de características gerais na qualidade de vida de pacientes com doença pulmonar obstrutiva crônica Influence of general clinical parameters on the quality of life of chr...
Published 2004-06-01“…CONCLUSIONS: The BMI and 6MWT were shown to have an influence on quality of life in the COPD patients studied. Therefore, therapeutic approaches to improving the quality of life of COPD patients should take these indices into consideration.…”
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12370
Cirurgia vídeo-assistida para a ablação da fibrilação atrial isolada por radiofrequência bipolar Cirugía videoasistida para ablación de fibrilación atrial aislada por radiofrecuenc...
Published 2009-10-01“…<br>BACKGROUND: The prevalence of atrial fibrillation, expenses with the healthcare system and the associated high morbidity and mortality have justified the search for new therapeutic approaches. OBJECTIVE: To evaluate the reproducibility of the surgical technique, its safety and the initial outcome of the video-assisted surgery for the isolated atrial fibrillation ablation with bipolar radiofrequency. …”
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12371
Neurogenetics and Epigenetics of Loneliness
Published 2023-11-01“…Identification of the individual contributions by various (epi)genetic factors presents opportunities for the creation of innovative preventive, diagnostic, and therapeutic approaches for individuals who cope with persistent feelings of loneliness. …”
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12372
Hemograma de cães envenenados experimentalmente com Bothrops alternatus após diferentes tratamentos.
Published 2005-03-01“…Palavras-chave: Hemograma, Bothrops, cão SUMMARY: The aim of this study was to evaluate hemograms of dogs experimentally envenomed with Bothrops alternatus following different therapeutic approaches (specific anti-venom serum, flunixin meglumine and aqueous extract of Curcuma longa). …”
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12373
Alice Parfitt - Thesis submitted in partial fulfilment of the degree of Doctor of Clinical Psychology (DClinPsych)
Published 2022“…</p> <p><b>Discussion:</b> Recommendations for psychological support in LCCs are suggested. Therapeutic approaches focused on (i) adjusting to CKD (such as Cognitive Behavioural Therapy and Acceptance and Commitment Therapy), (ii) symptom reduction (e.g. pain-management or mindfulness-based interventions) and (iii) systemic-focused interventions may be particularly helpful.…”
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Selected Lectures of the 18th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 19-22, 2022
Published 2022-10-01“…PREECLAMPSIA, FETAL INTRAUTERINE GROWTH RESTRICTION AND MATERNAL CARDIOVASCULAR ADAPTATION: A KEY TO FIND A NEW THERAPEUTICAL APPROACH • H. Valensise, D. Farsetti, F. Pometti, B. …”
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Патогенетические механизмы фибрилляции предсердий и формирования предсердного фиброза = Pathogenic mechanisms of atrial fibrillation and atrial fibrosis formation...
Published 2016-10-01“…This paper reviews the current understanding of how atrial fibrosis creates a substrate for AF, summarizes available data on the mechanisms of fibrosis and its distribution, and highlights the therapeutic approaches aimed at reducing the structural remodeling to prevent AF. …”
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12376
Fibrose pulmonar idiopática: apresentação clÃnica, evolução e fatores de prognóstico basais numa coorte portuguesa
Published 2013-01-01“…These results could mean different physiopathologic pathways, which could implicate different therapeutic approaches. Palavras-chave: Fibrose pulmonar idiopática, Sobrevivência, Prognóstico, Keywords: Idiopathic Pulmonary Fibrosis, Survival, Prognosis…”
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12377
Psychosocial interventions for self-harm in adults.
Published 2016“…Casemanagement and remote contact interventions did not appear to have any benefits in terms of reducing repetition of SH. Other therapeutic approaches weremostly evaluated in single trials ofmoderate to very low quality such that the evidence relating to these interventions is inconclusive.…”
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Artificial Intelligence and Healthcare
Published 2022-11-01“…For healthcare applications, the machine learning allows phenotyping of individuals’ health facilitating targeted diagnostic or therapeutic approaches to diseases. AI with natural language processing can be applied for clinical data to extract information from free text such as clinical observations or health journals and converting into standard clinical terminologies. …”
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COVID-19 associated mucormycosis – a recent challenge
Published 2023-04-01“…Surgery plus antimycotic agent (61%), antimycotic therapy alone (28%), and surgery alone (11%) were the therapeutic approaches. All neonatal patients underwent a surgical procedure; posaconazole (30%) and isavuconazole (11%) effectively treated these patients.5 The authors commented on low immunity during the COVID-19 pandemic favoring the high prevalence of mucormycosis in India and the difficulties of early diagnosis and treatment.5 Divakar6 reviewed data about mucormycosis in general and the cases associated with the two waves of COVID-19 infections in India.6 The estimated mortality rate of mucormycosis (50%) may be over 90% if untreated; Rhizopus arrhizus was the most common agent of human mucormycosis described in Indian patients, followed by Apophysomyces variabilis, R. microsporus, and R. homothallicus.6 Mucormycosis among COVID-19 patients, including the mortality rate, are increasing in India and some of the neighboring countries such as Bangladesh, Nepal, and Pakistan.6 Because of species-specific differences, there are therapeutic challenges in India, with only three potentially efficient drugs (amphotericin B, posaconazole, and isavuconazole). …”
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