GENETIC POLIMORPHISMS OF ENZYMES INVOLVED IN FOLATE METABOLISM IN HEALTHY SLOVENIAN POPULATION by Petra Bohanec, Vita Dolžan

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Regulation of 5‐fluorodeoxyuridine monophosphate‐thymidylate synthase ternary complex levels by autophagy confers resistance to 5‐fluorouracil by Nana Nishizawa, Chinatsu Kurasaka, Yoko Ogino, Akira Sato

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Activity of pemetrexed in recurrent, metastatic sacral chordoma: A case report by Dominique G. Celestino, Lara E. Davis, Santosh Kesari

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Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine by Stefano Vitello, Italia Di Liegro, Maria Rita Ricciardi, Chiara Verga, Alessandra Amato, Gabriella Schiera, Carlo Di Liegro, Giuseppe Messina, Patrizia Proia

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Administration of adjuvant oral tegafur/uracil chemotherapy post hepatocellular carcinoma resection: A randomized controlled trial by Mitsuru Ishizuka, Keiichi Kubota, Takehiko Nemoto, Mitsugi Shimoda, Masato Kato, Yukihiro Iso, Kazuma Tago

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Development and validation a radiomics nomogram for predicting thymidylate synthase status in hepatocellular carcinoma based on Gd-DTPA contrast enhanced MRI by Zongren Ding, Yijun Wu, Guoxu Fang, Zhaowang Lin, Kongying Lin, Jun Fu, Qizhen Huang, Yanyan Tang, Wuyi You, Jingfeng Liu, Yongyi Zeng

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Crystal structures of thymidylate synthase from nematodes, Trichinella spiralis and Caenorhabditis elegans, as a potential template for species-specific drug design by Dowierciał Anna, Wilk Piotr, Rypniewski Wojciech, Frączyk Tomasz, Jarmuła Adam, Banaszak Katarzyna, Dąbrowska Magdalena, Cieśla Joanna, Rode Wojciech

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Review of Prodrug and Nanodelivery Strategies to Improve the Treatment of Colorectal Cancer with Fluoropyrimidine Drugs by Santu Sarkar, Sezgin Kiren, William H. Gmeiner

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Alvaxanthone, a Thymidylate Synthase Inhibitor with Nematocidal and Tumoricidal Activities by Piotr Maj, Mattia Mori, Justyna Sobich, Joanna Markowicz, Łukasz Uram, Zbigniew Zieliński, Deborah Quaglio, Andrea Calcaterra, Ylenia Cau, Bruno Botta, Wojciech Rode

Subjects: “…thymidylate synthase…”
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Visfatin and Resveratrol Differentially Regulate the Expression of Thymidylate Synthase to Control the Sensitivity of Human Colorectal Cancer Cells to Capecitabine Cytotoxicity by Kuen-Lin Wu, Ko-Chao Lee, Chia-Kuang Yen, Cheng-Nan Chen, Shun-Fu Chang, Wen-Shih Huang

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Relationship between the Expression of the Thymidylate Synthase and the Prognosis of Gastric Cancer Patients Treated with Combinational Chemotherapy Regimen Including Fluorouracil,... by Mozaffar Aznab, Seyed Majid Ahmadi, Sedigheh Khazaei, Seyed Mojtaba Ahmadi, Mansour Khazaei, Hamid Hamdi

Subjects: “…Thymidylate synthase; Gastric cancer; 5- fluorouracil; Survival; Chemotherapy…”
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Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells by Changwon Yang, Jisoo Song, Sunjae Hwang, Jungil Choi, Gwonhwa Song, Whasun Lim

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One day versus two days of hepatic arterial infusion with oxaliplatin and fluorouracil for patients with unresectable hepatocellular carcinoma by Zhicheng Lai, Yexing Huang, Dongsheng Wen, Xuanjia Lin, Anna Kan, Qijiong Li, Wei Wei, Minshan Chen, Li Xu, Minke He, Ming Shi

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Analysis of the TSER and G>C variants in the TYMS gene: a high frequency of low expression genotypes predicted in the Mexican population by Alma Faviola Favela-Mendoza, Andrea Dinorah Godínez-López, Mariana Chávez-Arreguin, José Alonso Aguilar-Velázquez, Gabriela Martínez-Cortes, Héctor Rangel-Villalobos

Subjects: “…thymidylate synthase…”
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Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4 by Cong Hu, Xinhua Chen, Xu Lin, Jun Dai, Jiang Yu

Subjects: “…Thymidylate synthase inhibitor…”
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Mechanistic and structural basis for inhibition of thymidylate synthase ThyX by Tamara Basta, Yap Boum, Julien Briffotaux, Hubert F. Becker, Isabelle Lamarre-Jouenne, Jean-Christophe Lambry, Stephane Skouloubris, Ursula Liebl, Marc Graille, Herman van Tilbeurgh, Hannu Myllykallio

Subjects: “…thymidylate synthase thyx…”
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Effect of PD-L1 expression on the efficacy of pemetrexed-based chemotherapy in patients with advanced lung adenocarcinoma and its mechanism by SHI Maolin , BAI Yudi , WANG Chao , LI Siqi , ZHOU Daijun , PENG Jingjing , SUN Feifan , LI Dong , ZHANG Tao

Subjects: “…lung adenocarcinoma| pd-l1|thymidylate synthase| pemetrexed…”
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Crystal structures of complexes of mouse thymidylate synthase crystallized with N4-OH-dCMP alone or in the presence of N5,10-methylenetetrahydrofolate by Dowierciał Anna, Jarmuła Adam, Wilk Piotr, Rypniewski Wojciech, Kierdaszuk Borys, Rode Wojciech

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Corrigendum: Targeting thymidylate synthase enhances the chemosensitivity of triple-negative breast cancer towards 5-FU-based combinatorial therapy by Nair Hariprasad Haritha, Akbar Nawab, Vinod Vijayakurup, Nikhil Ponnoor Anto, Vijayasteltar B. Liju, Vijai V. Alex, Areekkara Nisthul Amrutha, Sreekumar U. Aiswarya, Mundanattu Swetha, Balachandran S. Vinod, Sankar Sundaram, Maria V. Guijarro, Thomas Herlevich, Archana Krishna, Nesteena K. Nestory, Smitha V. Bava, Chittalakkottu Sadasivan, Maria Zajac-Kaye, Ruby John Anto

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Prognostic value of folate-associated gene expression in stage II colon cancer by Donia Kaidi, Elisabeth Odin, Yvonne Wettergren, Elinor Bexe Lindskog

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