Strumos chirurginio gydymo pavojai: pooperacinis balso klosčių paralyžius by Algimantas Žindžius, Virgilijus kKrasauskas, Jelena Jončiauskienė

“…The injuries to the recurrent laryngeal nerve are determined by both objective (thyroid gland pathology, thyroid cancer, recurrence of goiter, long-lasting medical treatment, unfavorable variants of thyroid gland and adjacent anatomic structures and the extent of operation) and subjective factors (methods of operation, surgeon’s experience, operative technique). …”
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Proteasome inhibitors in medullary thyroid carcinoma: time to restart with clinical trials? by Giuseppe Fanciulli, Giuseppe Fanciulli, Roberta Modica, Anna La Salvia, Erika Maria Grossrubatscher, Tullio Florio, Tullio Florio, Francesco Ferraù, Alessandro Veresani, Flaminia Russo, Annamaria Colao, Annamaria Colao, Antongiulio Faggiano

“…IntroductionMedullary thyroid cancer (MTC) is a rare thyroid tumour whose management in advanced stages is challenging, despite effective therapeutic options having expanded in recent years. …”
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Quantification of Boron Compound Concentration for BNCT Using Positron Emission Tomography by Marcin Balcerzyk, Manuel De-Miguel, Carlos Guerrero, Begoña Fernandez

“…For future BNCT treatments of thyroid cancer, contrary to the ¹³¹I used now, there is no post-treatment radioactive decay, the patient can be immediately discharged from hospital, and there is no six-month moratorium for pregnancy. …”
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US-Elastography With Different Techniques for Thyroid Nodule Characterization: Systematic Review and Meta-analysis by Vito Cantisani, Annalisa De Silvestri, Valeria Scotti, Daniele Fresilli, Maria Grazia Tarsitano, Giorgia Polti, Olga Guiban, Eleonora Polito, Patrizia Pacini, Cosimo Durante, Giorgio Grani, Andrea M. Isidori, Elisa Giannetta, Salvatore Sorrenti, Pierpaolo Trimboli, Carlo Catalano, Roberto Cirocchi, Augusto Lauro, Vito D’Andrea

“…BackgroundThyroid nodules are frequent in adult population and thyroid cancer incidence has increased dramatically over the past three decades. …”
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Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx] by Stefano Bonassi, Giulia Prinzi, Palma Lamonaca, Patrizia Russo, Irene Paximadas, Giuseppe Rasoni, Raffaella Rossi, Marzia Ruggi, Salvatore Malandrino, Maria Sánchez-Flores, Vanessa Valdiglesias, Barbara Benassi, Francesca Pacchierotti, Paola Villani, Martina Panatta, Eugenia Cordelli

“…Recently, concerns of the safety of the extract have been raised after a report from US National Toxicology Program (NTP) claimed high doses of GBLE increased liver and thyroid cancer incidence in mice and rats. A safety study has been designed to assess, in a population of elderly residents in nursing homes, clinical and genomic risks associated to GBLE treatment. …”
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En bloc resection of total thyroid and bilateral central compartment lymph nodes via a gasless transoral approach in papillary thyroid carcinoma by Xuren Sheng, Xuren Sheng, Jianjun Liu, Jianjun Liu, Jing Fang, Jing Fang, Xucai Zheng, Xucai Zheng, Shengying Wang, Shengying Wang

“…Therefore, this technique may be a better surgical method for patients with bilateral thyroid cancer and cosmetic needs.…”
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International patterns and trends of childhood and adolescent cancer, 1978-2012 by Yawen Zhao, Peiyuan Sun, Jingyuan Xiao, Lan Jin, Ning Ma, Zhe Li, Guoshuang Feng, Huang Huang, Nicole C. Deziel, Xiaomei Ma, Xin Ni, Yawei Zhang

“…The incidence of thyroid cancer among adolescents increased in most regions and that of testicular cancer decreased in approximately one-half of the regions studied. …”
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Advances in Detecting Low Prevalence Somatic TERT Promoter Mutations in Papillary Thyroid Carcinoma by Vitor Rodrigues da Costa, Larissa Valdemarin Bim, Luiza Dornelles Penteado Pacheco e Silva, Gabriel Avelar Colloza-Gama, André Uchimura Bastos, André Uchimura Bastos, Rosana Delcelo, Gisele Oler, Janete Maria Cerutti

“…Although far more frequent in the poorly differentiated and undifferentiated thyroid cancer, the TERT promoter mutations play a significant role on PTC recurrence and disease-specific mortality. …”
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Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis by Xiang Xiao, Xuanyu Wu, Lu Yi, Fengming You, Fengming You, Xueke Li, Chong Xiao, Chong Xiao

“…Ten hub genes were identified, which mainly enriched in pathways including maturity onset diabetes of the young, thyroid cancer, gastric acid secretion, longevity regulating pathway, melanogenesis, and pancreatic secretion.ConclusionThe presence of T2DM does not increase the risk of CRC or IBD. …”
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Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification by Nathan L. DeBono, Robert D. Daniels, Laura E. Beane Freeman, Judith M. Graber, Johnni Hansen, Lauren R. Teras, Tim Driscoll, Kristina Kjaerheim, Paul A. Demers, Deborah C. Glass, David Kriebel, Tracy L. Kirkham, Roland Wedekind, Adalberto M. Filho, Leslie Stayner, Mary K. Schubauer-Berigan

“…Results: Among the 16 included cancer incidence studies, the estimated meta-rate ratio, 95% confidence interval (CI), and heterogeneity statistic (I2) for ever-employment as a career firefighter compared mostly to general populations were 1.58 (1.14–2.20, 8%) for mesothelioma, 1.16 (1.08–1.26, 0%) for bladder cancer, 1.21 (1.12–1.32, 81%) for prostate cancer, 1.37 (1.03–1.82, 56%) for testicular cancer, 1.19 (1.07–1.32, 37%) for colon cancer, 1.36 (1.15–1.62, 83%) for melanoma, 1.12 (1.01–1.25, 0%) for non-Hodgkin lymphoma, 1.28 (1.02–1.61, 40%) for thyroid cancer, and 1.09 (0.92–1.29, 55%) for kidney cancer. …”
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Network Pharmacology Combined with Transcriptional Analysis to Unveil the Biological Basis of Astaxanthin in Reducing the Oxidative Stress Induced by Diabetes Mellitus by Sun X, Ji Y, Tahir A, Kang J

“…The differentially expressed genes were enriched in euchromatin, thyroid cancer, and metaphase-plate congression. Three Ast-intersecting targets — Col5A1, Nqo1, and Notch2 — were then identified. …”
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Improved technique thyroidectomy with lateral modified radical neck dissection by A V Shabunin, D D Dolidze, S O Podvyaznikov, K V Melnik, R B Mumladze, A V Vardanyan, I N Lebedinskiy, P V Grachev

“…According to World Health Organization thyroid cancer (TC) is the most common endocrine malignancy. …”
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Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study by Hidekazu Shirota, Keigo Komine, Masanobu Takahashi, Shin Takahashi, Eisaku Miyauchi, Hidetaka Niizuma, Hiroshi Tada, Muneaki Shimada, Tetsuya Niihori, Yoko Aoki, Ikuko Sugiyama, Maako Kawamura, Jun Yasuda, Shuhei Suzuki, Takeshi Iwaya, Motonobu Saito, Tsuyoshi Saito, Hiroyuki Shibata, Toru Furukawa, Chikashi Ishioka

“…The leading biomarkers that led to treatment recommendations were tumor mutational burden‐high (TMB‐H) (n = 32), ERBB2 amplification (n = 24), BRAF V600E (n = 16), and BRCA1/2 alterations (n = 32). Thyroid cancer accounted for most cancer cases for which treatment recommendation was provided (81.3%), followed by non‐small cell lung cancer (42.4%) and urologic cancer (31.3%). …”
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Targeting Aurora-A inhibits tumor progression and sensitizes thyroid carcinoma to Sorafenib by decreasing PFKFB3-mediated glycolysis by Zhi Jingtai, Hu Linfei, Qian Yuyang, Kang Ning, Yun Xinwei, Wang Xin, Ruan Xianhui, Huang Dongmei, Yang Weiwei, Meng Xiangrui, Zhu Tianze, Wang Wei, Zheng Xiangqian

“…Abstract Thyroid cancer (TC) is the most common endocrine tumor, amongst which anaplastic thyroid carcinoma (ATC) is the most deadly. …”
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Association between exposure to radioactive iodine after the Chernobyl accident and thyroid volume in Belarus 10-15 years later by Ekaterina Chirikova, Robert J. McConnell, Patrick O’Kane, Vasilina Yauseyenka, Mark P. Little, Victor Minenko, Vladimir Drozdovitch, Ilya Veyalkin, Maureen Hatch, June M. Chan, Chiung-Yu Huang, Kiyohiko Mabuchi, Elizabeth K. Cahoon, Alexander Rozhko, Lydia B. Zablotska

“…Abstract Background While there is a robust literature on environmental exposure to iodine-131 (131I) in childhood and adolescence and the risk of thyroid cancer and benign nodules, little is known about its effects on thyroid volume. …”
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Association between use of antihypertensive drugs and the risk of cancer: a population-based cohort study in Shanghai by Suna Wang, Li Xie, Jianlin Zhuang, Ying Qian, Guanglu Zhang, Xiaowei Quan, Lei Li, Herbert Yu, Weituo Zhang, Wensui Zhao, Biyun Qian

“…The second commonly used drug ARBs were also associated with increased risk of total cancer (HR = 1.10, 95%CI: 1.03–1.17) as well as lung and thyroid cancers (HR = 1.21, 95%CI: 1.05–1.39; HR = 1.62 95%CI: 1.18–2.21, respectively). …”
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Causal relationship between genetically predicted depression and cancer risk: a two-sample bi-directional mendelian randomization by Guang-Li Zhu, Cheng Xu, Kai-bin Yang, Si-Qi Tang, Ling-Long Tang, Lei Chen, Wen-Fei Li, Yan-Ping Mao, Jun Ma

“…Methods We performed the two-sample bi-directional mendelian randomization with the publicly available GWAS summary statistics to investigate the causal relationship between the genetically predicted depression and the risk of multiple types of cancers, including ovarian cancer, breast cancer, lung cancer, glioma, pancreatic cancer, lymphoma, colorectal cancer, thyroid cancer, bladder cancer, and kidney cancer. The total sample size varies from 504,034 to 729,150. …”
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Cancers and COVID-19 Risk: A Mendelian Randomization Study by Zengbin Li, Yudong Wei, Guixian Zhu, Mengjie Wang, Lei Zhang

“…The corresponding <i>p</i>-values for the casual associations were all statistically insignificant: overall cancer (<i>p</i> = 0.34; <i>p</i> = 0.42; <i>p</i> = 0.69), lung cancer (<i>p</i> = 0.60; <i>p</i> = 0.37; <i>p</i> = 0.96), breast cancer (<i>p</i> = 0.43; <i>p</i> = 0.74; <i>p</i> = 0.43), endometrial cancer (<i>p</i> = 0.79; <i>p</i> = 0.24; <i>p</i> = 0.83), prostate cancer (<i>p</i> = 0.54; <i>p</i> = 0.17; <i>p</i> = 0.58), thyroid cancer (<i>p</i> = 0.70; <i>p</i> = 0.80; <i>p</i> = 0.28), ovarian cancer (<i>p</i> = 0.62; <i>p</i> = 0.96; <i>p</i> = 0.93), melanoma (<i>p</i> = 0.79; <i>p</i> = 0.45; <i>p</i> = 0.82), small bowel cancer (<i>p</i> = 0.09; <i>p</i> = 0.08; <i>p</i> = 0.19), colorectal cancer (<i>p</i> = 0.85; <i>p</i> = 0.79; <i>p</i> = 0.30), oropharyngeal cancer (<i>p</i> = 0.31; not applicable, NA; <i>p</i> = 0.80), lymphoma (<i>p</i> = 0.51; NA; <i>p</i> = 0.37) and cervical cancer (<i>p</i> = 0.25; <i>p</i> = 0.32; <i>p</i> = 0.68). …”
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Prevalence and factors of COVID-19 vaccine refusal among solid cancer patients in China: an application of the health belief model by Zhaomin Xie, Zhaomin Xie, Zhaomin Xie, Joseph Tak-Fai Lau, Joseph Tak-Fai Lau, Joseph Tak-Fai Lau, Joseph Tak-Fai Lau, Yuanke Liang, Qiaolei Ouyang, Junjia Chen, Si Lin, Kaitao Yao, Xuanyin Hu, Haoyu Lin, Yanqiu Yu, De Zeng, De Zeng

“…This study investigated factors of vaccine refusal based on the Health Belief Model (HBM).MethodsA cross-sectional study was conducted among female breast cancer patients, male/female thyroid cancer patients, and gynecological cancer patients in Shantou, China from April to August 2022 (n = 1,115). …”
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Cancer in Africa: The Untold Story by Yosr Hamdi, Yosr Hamdi, Ines Abdeljaoued-Tej, Ines Abdeljaoued-Tej, Afzal Ali Zatchi, Afzal Ali Zatchi, Sonia Abdelhak, Samir Boubaker, Samir Boubaker, Joel S. Brown, Alia Benkahla

“…With the exception of thyroid cancer, all other cancers have higher incidences in males than females.ConclusionOur results show that the African continent suffers from a shortage of medical equipment, research resources and epidemiological expertise. …”
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