A Descriptive Study of the Types and Survival Patterns of Saudi Patients with Multiple Primary Solid Malignancies: A 30-Year Tertiary Care Center Experience by Moustafa S. Alhamadh, Rakan B. Alanazi, Sultan T. Algarni, Ahmed Abdullah R. Alhuntushi, Mohammed Qasim Alshehri, Yusra Sajid Chachar, Mohammad Alkaiyat, Fouad Sabatin

“…The most frequent site of the first primary malignancy was breast cancer, followed by colorectal, skin, and thyroid cancers. The most frequent site of the second primary malignancy was colorectal cancer, followed by thyroid, breast, and liver cancers. …”
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Role of Transmembrane 4 L Six Family 1 in the Development and Progression of Cancer by Fangmei Fu, Xudong Yang, Minying Zheng, Qi Zhao, Kexin Zhang, Zugui Li, Hao Zhang, Shiwu Zhang

“…TM4SF1 has been shown to be overexpressed in many malignant tumors, including gliomas; malignant melanomas; and liver, prostate, breast, pancreatic, bladder, colon, lung, gastric, ovarian, and thyroid cancers. TM4SF1 promotes the migration and invasion of cancer cells by inducing epithelial-mesenchymal transition, self-renewal ability, tumor angiogenesis, invadopodia formation, and regulating the related signaling pathway. …”
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Controlled release of gallium maltolate complex from injectable phosphocalcic cements by Manon Dupleichs, Maxence Limelette, Charlotte Mellier, Valérie Montouillout, François-Xavier Lefevre, Sophie Quillard, Jean-Yves Mevellec, Pascal Janvier

“…Some cancers have tropism for bone: breast, prostate, lung, kidney, and thyroid cancers are the most common. Bone metastases can be treated with surgical resection and the resulting bone defects can be filled with injectable biomaterials. …”
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Frequency of Promoter Mutations in Real-World Analysis of 2,092 Thyroid Carcinoma Patients by Heera Yang, Hyunju Park, Hyun Jin Ryu, Jung Heo, Jung-Sun Kim, Young Lyun Oh, Jun-Ho Choe, Jung Han Kim, Jee Soo Kim, Hye Won Jang, Tae Hyuk Kim, Sun Wook Kim, Jae Hoon Chung

“…Advanced T stage, advanced N stage, and distant metastasis at diagnosis were highly prevalent in mutated thyroid cancers. However, initial distant metastasis was not present in patients with TERT promoter mutations in PTMC. …”
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Prevalence of subclinical lung cancer detected at autopsy: a systematic review by Asha Bonney, Kayo Togawa, Michelle Ng, Michael Christie, Kwun M Fong, Henry Marshall, Katharine See, Cameron Patrick, Daniel Steinfort, Renee Manser

“…Compared to autopsy systematic reviews in breast, prostate and thyroid cancers, the pooled prevalence is lower in lung cancer for subclinical cancer. …”
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Survival and prognostic factors for survival, cancer specific survival and disease free interval in 239 patients with Hurthle cell carcinoma: a single center experience by Branisav Oluic, Ivan Paunovic, Zlatibor Loncar, Vladimir Djukic, Aleksandar Diklic, Milan Jovanovic, Zeljko Garabinovic, Nikola Slijepcevic, Branislav Rovcanin, Dusan Micic, Aleksandar Filipovic, Vladan Zivaljevic

“…Abstract Background Hurthle cell carcinoma makes up 3 to 5% of all thyroid cancers and is considered to be a true rarity. …”
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Risk of cardiovascular diseases in cancer patients: A nationwide representative cohort study in Taiwan by Tzu-Lin Yeh, Min-Shu Hsu, Hsin-Yin Hsu, Ming-Chieh Tsai, Jing-Rong Jhuang, Chun-Ju Chiang, Wen-Chung Lee, Kuo-Liong Chien

“…We focused on colorectal cancer, women’s breast cancer, lung cancer, liver cancer, oral cancer, prostate cancer, and thyroid cancers. The study endpoint was fatal and non-fatal CVD, which was defined as ischemic heart disease and ischemic stroke according to the National Health Insurance Research Database. …”
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Value of cytokeratin-19, Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms by Rajasekhar Sanuvada, Rukmangadha Nandyala, Amit Kumar Chowhan, Phaneendra Bobbidi, Mutheeswariah Yootla, Narendra Hulikal, Alok Sachan

“…BACKGROUND: Diagnosis of types and aggressiveness of thyroid cancers is difficult. The "gold standard" in diagnosis is using routine hematoxylin and eosin staining. …”
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Thyroid Collision Tumors: The Presence of the Medullary Thyroid Carcinoma Component Negatively Influences the Prognosis by Ion Negura, Victor Ianole, Mihai Danciu, Cristina Preda, Diana Gabriela Iosep, Radu Dănilă, Alexandru Grigorovici, Delia Gabriela Ciobanu Apostol

“…Thyroid collision tumors (TCTs) are rare pathological findings, representing <1% of thyroid cancers. This study aimed to compare the main pathological features of TCTs containing medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) components with MTC-only tumors and PTC-only tumors. …”
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Increased risk of malignancy in patients with systemic lupus erythematosus: population-based cohort study in Korea by Jung-Yong Han, Hyoungyoung Kim, Sun-Young Jung, Eun Jin Jang, Soo-Kyung Cho, Yoon-Kyoung Sung

“…In SLE patients, breast and reproductive system and thyroid cancers occurred predominantly, followed by liver and colon cancers. …”
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Role of Alternatively Spliced Messenger RNA (mRNA) Isoforms of the Insulin-Like Growth Factor 1 (IGF1) in Selected Human Tumors by Aldona Kasprzak, Witold Szaflarski

“…This review highlights the role of IGF1 isoform expression (mRNAs, proteins) in physiology and different types of human tumors (e.g., breast cancer, cervical cancer, colorectal cancer, osteosarcoma, prostate and thyroid cancers), as well as mechanisms of IGF1 spliced variants involvement in tumor biology.…”
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Comparing postoperative complication of LigaSure Small Jaw instrument with clamp and tie method in thyroidectomy patients: a randomized controlled trial [IRCT2014010516077N1] by Ali Ramouz, Seyed Ziaeddin Rasihashemi, Abdolrasoul Safaeiyan, Mahdie Hosseini

“…Methods All patients with the diagnosis of multinodular goiter, thyroid cancers, retrosternal goiter and other indications for thyroid surgeries, enrolled. …”
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Incidence and Survival for Head and Neck Cancers in Estonia, 1996&ndash;2016: A Population-Based Study by Kase S, Baburin A, Kuddu M, Innos K

“…The latest 5-year RSR was 90% for thyroid cancers (99% for papillary carcinoma). Large female survival advantage was seen for most sites.Conclusion: The observed trends suggest an emerging role of HPV infection in combination with traditional risk factors in the development of head and neck cancers in Estonia. …”
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Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. by Junaid Abdulghani, Joshua E Allen, David T Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D Smith, Robin Humphreys, Wafik S El-Deiry

“…This panel included human breast, prostate, colon, liver and thyroid cancers. The cooperativity of these combinations was also observed in vivo, as measured by tumor volume and TUNEL staining as a measure of apoptosis. …”
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Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma. by Willem E Corver, Dina Ruano, Karin Weijers, Wietske C E den Hartog, Merlijn P van Nieuwenhuizen, Noel de Miranda, Ronald van Eijk, Anneke Middeldorp, Ekaterina S Jordanova, Ekaterina S Jordanova, Jan Oosting, Ellen Kapiteijn, Guido Hovens, Jan Smit, Tom van Wezel, Hans Morreau

“…We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). …”
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Galectin-3 and Beclin1/Atg6 genes in human cancers: using cDNA tissue panel, qRT-PCR, and logistic regression model to identify cancer cell biomarkers. by Halliday A Idikio

“…Breast, kidney and thyroid cancers had high galectin-3 levels and low Beclin1 levels.…”
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The loss of the p53 activator HIPK2 is responsible for galectin-3 overexpression in well differentiated thyroid carcinomas. by Luca Lavra, Cinzia Rinaldo, Alessandra Ulivieri, Emidio Luciani, Paolo Fidanza, Laura Giacomelli, Carlo Bellotti, Alberto Ricci, Maria Trovato, Silvia Soddu, Armando Bartolazzi, Salvatore Sciacchitano

“…Therefore, HIPK2 can be considered as a new tumour suppressor gene for thyroid cancers.…”
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Integrated transcriptome sequencing and weighted gene co-expression network analysis reveals key genes of papillary thyroid carcinomas by Lingfeng Pan, Lianbo Zhang, Jingyao Fu, Keyu Shen, Guang Zhang

“…Objective: Papillary thyroid carcinoma (PTC) accounts for the majority of thyroid cancers and has a high recurrence rate. We aimed to screen key genes involved in PTC to provide novel insights into the mechanisms of PTC. …”
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Risk of Second Primary Malignancies Based on the Histological Subtypes of Colorectal Cancer by Meijuan Wu, Mengxi Huang, Chenglong He, Cheng Chen, Cheng Chen, Huiyu Li, Jing Wang, Mengyan Liu, Gongbo Fu, Gongbo Fu, Zengjie Lei, Zengjie Lei, Xiaoyuan Chu, Xiaoyuan Chu

“…Increased risks of second stomach, uterus, urinary bladder, kidney, and thyroid cancers were only observed in CA patients, while increased risk of second renal pelvis cancer was limited to MA patients. …”
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<i>CHEK2^p.I157T</i> Mutation Is Associated with Increased Risk of Adult-Type Ovarian Granulosa Cell Tumors by Peter Švajdler, Peter Vasovčák, Marián Švajdler, Monika Šedivcová, Veronika Urbán, Michal Michal, Roman Mezencev

“…Pathogenic germline mutations c.1100delC and p.I157T in the <i>CHEK2</i> gene have been associated with increased risk of breast, colon, kidney, prostate, and thyroid cancers; however, no associations have yet been identified between these two most common European founder mutations of the <i>CHEK2</i> gene and ovarian cancers of any type. …”
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