Finger millet RNA-seq reveals differential gene expression associated with tolerance to aluminum toxicity and provides novel genomic resources by Haftom Brhane, Haftom Brhane, Haftom Brhane, Teklehaimanot Haileselassie, Kassahun Tesfaye, Kassahun Tesfaye, Rodomiro Ortiz, Cecilia Hammenhag, Kibrom B. Abreha, Ramesh R. Vetukuri, Mulatu Geleta

“…Among the significant DEGs, 54.7% were annotated in the GO database with the top hits being ATP binding (GO:0005524) and DNA binding (GO:0003677) in the molecular function, DNA integration (GO:0015074) and cell redox homeostasis in the biological process, as well as cellular anatomical entity and intracellular component in the cellular component GO classes. …”
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TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma by Kara M. Ruicci, Jalna Meens, Paul Plantinga, William Stecho, Nicole Pinto, John Yoo, Kevin Fung, Danielle MacNeil, Joe S. Mymryk, John W. Barrett, Christopher J. Howlett, Paul C. Boutros, Laurie Ailles, Anthony C. Nichols

“…We then used reverse phase protein arrays (RPPAs) to profile the expression of proteins in parental and drug-resistant models. Top hits were validated by immunoblotting and immunohistochemistry. …”
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Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti-<i>Mycobacterium ulcerans</i> Natural Product-Derived Compounds by Samuel K. Kwofie, Kweku S. Enninful, Jaleel A. Yussif, Lina A. Asante, Mavis Adjei, Kwabena Kan-Dapaah, Elvis K. Tiburu, Wilhelmina A. Mensah, Whelton A. Miller, Lydia Mosi, Michael D. Wilson

“…The area under the curve (AUC) values greater than 0.7 were obtained for the computed Receiver Operating Characteristics (ROC) curves, validating the docking protocol. The identified top hits were pharmacologically profiled using Absorption, Distribution, Metabolism, Elimination and Toxicity (ADMET) predictions and their binding mechanisms were characterized. …”
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A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy by Shuwei Liu, Haoyi Fu, Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, Cindy M. Anderson, Carl A. Hubel, James M. Roberts, Arun Jeyabalan, Daniel E. Weeks, Mandy J. Schmella

“…Additional research is warranted for cg16155413/cg21882990, as well as top hits in trimesters 1–2 and significant DMRs that were not examined in the replication phase.…”
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