Advanced Functionalized CeO₂/Al₂O₃ Nanocomposite Sensor for Determination of Opioid Medication Tramadol Hydrochloride in Pharmaceutical Formulations by Seham S. Alterary, Maha F. El-Tohamy

Subjects: “…tramadol hydrochloride…”
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10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition by Gehad M. Elnagar, Mohamed M. Elseweidy, Yasmin K. Mahmoud, Nesreen M. I. M. Elkomy, Ziyad M. Althafar, Sultan F. Alnomasy, Naif A. Al-Gabri, Mohamed Shawky

Subjects: “…tramadol…”
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Alarmingly high prevalence of high-risk drug use among palestinian males: a cross-sectional study by Salwa Massad, Hadil Dalloul, Lina Adwan, Khalid Abu Saman, Rawan Kafri, Walaa Abu Alia, Marina Tucktuck, Lisa G. Johnston

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Toxicological Findings in a Possible Drug-drug Interaction Death: A Case Report by Mohammed Y. Albeishy, Magbool E. Oraiby, Ahmad M. Alamir, Ibrahim A. Khardali, Farid M. Abualsail, Ibraheem Mohammed Attafi

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Addition of 100 mg of Tramadol to 40 mL of 0.5% Ropivacaine for Interscalene Brachial Plexus Block Improves Postoperative Analgesia in Patients Undergoing Shoulder Surgeries as Compared to Ropivacaine Alone—A Randomized Controlled Study by Eleftheria Soulioti, Athanasia Tsaroucha, Alexandros Makris, Maria Koutsaki, Eirini Sklika, Argyro Mela, Panayiotis D. Megaloikonomos, Andreas F. Mavrogenis, Argyro Fassoulaki

Subjects: “…tramadol…”
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SeDeM tool-driven full factorial design for osmotic drug delivery of tramadol HCl: Formulation development, physicochemical evaluation, and in-silico PBPK modeling for predictive pharmacokinetic evaluation using GastroPlus™ by Muhammad Talha Saleem, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Farrukh Rafiq Ahmed, Kamran Ahmed, Fahad Siddiqui, Zafar Alam Mahmood, Muhammad Sikandar, Muhammad Suleman Imtiaz

Subjects: “…tramadol…”
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Association between Non-Steroidal Anti-Inflammatory Drugs Use and the Risk of Type 2 Diabetes Mellitus: A Nationwide Retrospective Cohort Study by Ming-Hsun Lin, Wen-Tung Wu, Yong-Chen Chen, Chieh-Hua Lu, Sheng-Chiang Su, Feng-Chih Kuo, Yu-Ching Chou, Chien-An Sun

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The dilemma of repeat weak opioid prescriptions – experiences from swedish GPs by Elsa Ekelin, Anders Hansson

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The Effect of Polymorphisms in the CYP2D6 and CYP2C9 Genes on the Clinical Efficacy of Tramadol and Ketorolac When Using the Accelerated Recovery Protocol in Patients With Uncomplicated Acute Calculous Cholecystitis Who Underwent Cholecystectomy by A. A. Muradyan, D. A. Blagovestnov, D. A. Sychev, P. A. Yartsev, M. L. Rogal, L. N. Kerimova, V. T. Koroshvili, I. A. Yepifanova

Subjects: “…tramadol…”
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P-015: A NON-INFERIORITY SINGLE-BLINDED RANDOMIZED CONTROLLED CLINICAL TRIAL ON THE EFFICACY OF ORAL MORPHINE VERSUS INJECTABLE TRAMADOL IN THE ANALGESIC MANAGEMENT OF SEVERE PAINFUL VASO-OCCLUSIVE CRISIS IN CHILDREN WITH SICKLE CELL DISEASE by ALIMA YANDA A., EPOSSE EKOUBE C., MAYI MBAM E., WETE E., MANDENG MA LINWA E., KOKI NDOMBO P.

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DAYA GUNA TRAMADOL 1 MG/KGBB DIBANDING PETIDIN 0,5 MG/KGBB YANG DIBERIKAN DRIP INTRAVENA SELAMA 10 MENIT UNTUK MENCEGAH MENGGIGIL PADA PASIEN SEKSIO SESARIA DENGAN ANESTESI SPINAL by , Kamala Kan Nur Azza, , Dr. Yusmein Uyun, Sp.An, KAO

“…An alternative drug, tramadol 1 mgkg-1 iv can be expected to prevent the spinal anasthetic shivering effectively and has a few complications. …”

REKOVER study protocol: a pRospective patient treatment rEgistry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in mOderate to seVere acutE pain in Real-world setting in Asia by Ankur Gupta, Suwimon Tangwiwat, Cesar Dimayuga, Kok Yuen Ho, Bibek Gyanwali, Edgar Michael Eufemio, Edwin Bernardo, Gopinathan Raju, Keen Wai Chong, Kritsadakorn Waithayayothin, Leonardo Ona, Marc Anthony L Castro, Passakorn Sawaddiruk, Roehl C Salvador, Sharifah Ahmad Roohi, Vajara Wilairatana, Zhi Hao Oon, Dinesh Nagrale

“…Introduction Satisfactory management of acute pain remains a major medical challenge despite the availability of multiple therapeutic options including the fixed-dose combination (FDC) drugs. Tramadol and dexketoprofen trometamol (TRAM/DKP) 75/25 mg FDC was launched in 2018 in Asia and is widely used in the management of moderate to severe acute pain. …”
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Short Onset and Enhanced Analgesia Following Nasal Administration of Non-Controlled Drugs in Nanovesicular Systems by Elka Touitou, Hiba Natsheh, Shatha Boukeileh, Rania Awad

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Opioid Prescribing for Osteoarthritis: Cross-Sectional Survey among Primary Care Physicians, Rheumatologists, and Orthopaedic Surgeons by Thomas J. Schnitzer, Rebecca L. Robinson, Lars Viktrup, Joseph C. Cappelleri, Andrew G. Bushmakin, Leslie Tive, Mia Berry, Chloe Walker, James Jackson

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Analgesic Effects and Impairment in Locomotor Activity Induced by Cannabinoid/Opioid Combinations in Rat Models of Chronic Pain by Mohammad Alsalem, Ahmad Altarifi, Mansour Haddad, Belal Azab, Heba Kalbouneh, Amer Imraish, Tareq Saleh, Khalid El-Salem

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Efficacy of serratus posterior superior intercostal plane block (SPSIPB) on post-operative pain and total analgesic consumption in patients undergoing video-assisted thoracoscopic... by Onur Avci, Oğuz Gundogdu, Fatih Balci, Muhammed N Tekcan, Mahmut Ozbey

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A comparison of postoperative analgesic efficacy of opioid-free anesthesia using intravenous paracetamol (15 mg/kg), lignocaine (2 mg/kg), and magnesium sulfate (20 mg/kg) versus standard opioid anesthesia using intravenous tramadol (2 mg/kg) for preemptive analgesia in abdominal surgeries under general anesthesia by Neena Jain, Neha Surendran, Meera Kumari, Pradeep Kumar, Veena Patodi, Kavita Jain

“…In this study, we will investigate the 24-h postsurgical analgesia and analgesic consumption with the use of OFA versus opioid anesthesia (tramadol) in patients undergoing abdominal surgery under general anesthesia. …”
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Effects of single-injection intercostal nerve block as a component of multimodal analgesia for pediatrics undergoing autologous auricular reconstruction: A double-blinded, prospect... by Kang Zheng, Bin Li, Jie Sun

“…Patients from group C received Tramadol 2 mg/kg by the end of the surgery as control. …”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…The active pharmaceutical ingredient is an organic, low molecular weight compound 4-(3,4-dibromothiophene carbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo [5,5,0,03,11,05,9]dodecane that was first synthesized according to computer modeling results at the IPCET SB RAS (Biysk).The likelihood of developing physical dependence was explored by per os administration of thiowurtzine and the reference drug tramadol twice a day for 5 days as follows: 1) at 9 a.m. – thiowurtzine 50 mg / kg and tramadol 10 mg / kg, at 3 p.m. – thiowurtzine 50 mg / kg and tramadol 10 mg / kg; 2) at 9 a.m. – thiowurtzine 50 mg / kg and tramadol 10 mg / kg, at 3 p.m. – thiowurtzine 75 mg / kg and tramadol 15 mg / kg; 3) at 9 a.m. – thiowurtzine 75 mg / kg and tramadol 15 mg / kg, at 3 p.m. – thiowurtzine 75 mg / kg and tramadol 15 mg / kg; 4) at 9 a.m. – thiowurtzine 100 mg / kg and tramadol 20 mg / kg, at 3 p.m. – thiowurtzine 100 mg / kg and tramadol 20 mg / kg; 5) at 9 a.m. – thiowurtzine 100 mg / kg and tramadol 20 mg / kg, at 3 p.m. – naloxone 10 mg / kg subcutaneously.In all the groups, the intensity of the withdrawal syndrome was studied by specific features in outbred male CD1 mice. …”
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Autonomic and hemodynamic effects of pre-anesthetic use of clonidine in healthy dogs by João Paulo da Exaltação Pascon, Fernanda Melo de Oliveira, Marilia Avila Valandro, Diane Jaqueline Waschburger, Roberto Thiesen

“…Six healthy adult mixed-breed dogs were administered a clonidine (clonidine group, CLG) and 30 days later, a placebo (control group, CG) preanesthetic protocol, in addition to propofol, isoflurane, and an bolus of tramadol and the continuous infusion thereafter. The total time mean values of HRV meanNN, SDNN, SDANN, SDNNI, and rMSSD were higher in the CL group, as observed in some HRV variables on tramadol bolus time (T4), tramadol continuous infusion (T8), and tracheal extubation time (T10). …”
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