The Effect of Gabapentin on Preoperative Anxiety and Postoperative Analgesia in Breast Cancer Surgery by Seda Kisi, Ersel Gulec, Mediha Turktan, Zehra Hatipoglu, Yasemin Gunes

“…Purpose: The goal of this study was to evaluate the effect of pre-emptive gabapentin administration on anxiety and on postoperative tramadol requirement in patients undergoing breast cancer surgery. …”
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تحضير مبعثرات صلبة للترامادول هيدروكلوريد بطريقة التجفيف بالإرذاذ by وهاد إبراهيم

“… Tramadol Hydorchloride is a centrally acting analgesic, which often used for the treatment of chronic and acute pain. …”
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تحضير مبعثرات صلبة للترامادول هيدروكلوريد بطريقة التجفيف بالإرذاذ by وهاد إبراهيم

“… Tramadol Hydorchloride is a centrally acting analgesic, which often used for the treatment of chronic and acute pain. …”
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Ultrasound guided peritubal infiltration of 0.25% Bupivacaine versus 0.25% Ropivacaine for postoperative pain relief after percutaneous nephrolithotomy: A prospective double blind... by Geeta P Parikh, Veena R Shah, Kalpana S Vora, Beena K Parikh, Manisha P Modi, Pratibha Kumari

“…Mean number of doses of tramadol and total consumption of tramadol in 24 h was less in Group R, though not statistically significant. …”
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Comparative evaluation of bupivacaine with magnesium sulphate and dexamethasone as adjuvants in ultrasound-guided transversus abdominis plane block for open unilateral inguinal her... by T Shambhavi, Saswati Das, Laxman K Senapati, Pulak P Padhi

“…Patients were assessed for the first 24 hours after surgery for pain at rest and movement using a numerical rating scale (NRS). Two mg/kg of tramadol was administered as rescue analgesia. The time to first demand tramadol, total consumption of tramadol, patient satisfaction score and side effects were evaluated. …”
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Femoral nerve block: assessment of postoperative analgesia in arthroscopic anterior cruciate ligament reconstruction by Úrsula Bueno do Prado Guirro, Elizabeth Milla Tambara, Fernanda Reinaldi Munhoz

“…Keywords: Postoperative analgesia, Femoral nerve block, Anterior cruciate ligament reconstruction, Spinal anesthesia, Tramadol, Adverse event…”
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Systemic Analgesia versus Continuous Erector Spinae Plane Block (ESPB) Infusion During Paediatric Nephrectomy: A Randomized, Controlled Trial by Adlan S, Abd El-Rahman A, Mohamed SAB, Thabet AM, Hamada EM, Farouk BR, El Sherif FA

“…Immediately postoperatively, Group E (ESPB group) received continuous ESPB with a PCA (patient controlled analgesia) pump at a rate of 0.2 mL/kg/hour bupivacaine 0.125%. Group T (Tramadol group), Tramadol hydrochloride was administered intravenously at a dose of 2 mg/kg/8hour, which could be increased to 2 mg/kg/6hours. …”
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Opioid analgesics-related pharmacokinetic drug interactions: from the perspectives of evidence based on randomized controlled trials and clinical risk management by Feng XQ, Zhu LL, Zhou Q

“…Circumstances in which opioid is comedicated as an object drug include rifampin–opioids (morphine, tramadol, oxycodone, methadone), quinidine–opioids (morphine, fentanyl, oxycodone, codeine, dihydrocodeine, methadone), antimycotics–opioids (buprenorphine, fentanyl, morphine, oxycodone, methadone, tilidine, tramadol), protease inhibitors–opioids (ritonavir, ritonavir/lopinavir–oxycodone, ritonavir–fentanyl, ritonavir–tilidine), grapefruit juice–opioids (oxycodone, fentanyl, methadone), antidepressants–opioids (paroxetine–tramadol, paroxetine–hydrocodone, paroxetine–oxycodone, escitalopram–tramadol), metoclopramide–morphine, amantadine–morphine, sumatriptan–butorphanol nasal sprays, ticlopidine–tramadol, St John’s wort–oxycodone, macrolides/ketolides–oxycodone, and levomepromazine–codeine. …”
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Comparing Continuous and Intermittent Infusion Effects on Serratus Anterior Plane Blocks in Video-Assisted Thoracoscopic Surgery: A Randomized Clinical Trial by He K, Meng Y, Zhu Y, Wang S, Zong Y

“…As compared to the CI group, the PIBI group consumed less tramadol during the first 24 hours (145 mg [87.5, 210] vs 190 mg [140, 400], p=0.012). …”
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Ultrasound-Guided Erector Spinae Plane Block versus Oblique Subcostal Transversus Abdominis Plane Block for Post-Operative Analgesia of Adult Patients Undergoing Laparoscopic Chole... by Muhammad Ali, Bilal Yasin, Sidra Khan, Iftikhar Ali, Hassam Abdullah, Humayun Munir Tarar

“…Post-operatively, Acetaminophen 1g IV 8 hourly was given to all patients, and in addition, Tramadol was used as rescue analgesia. Endpoints included comparing total Tramadol usage and Numerical Rating Scale scores between respective Groups. …”
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Evaluation of Postoperative Analgesic Consumption After Emergency and Elective Cesarean Section by Hakan Tapar, Serkan Karaman, Serkan Dogru, Tugba Karaman, Hatice Yilmaz Dogru

“…In patients under spinal anesthesia, total tramadol consumption was found to be 169.58±59.52 mg and 160.62±70.47 mg in emergency and elective cases respectively (p>0.05). …”
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Analgesic efficacy of systemic ketamine and lignocaine for pre-emptive multimodal analgesia in dogs by Kaka, Ubedullah

“…Results showed that the combination of ketamine-lidocaine-tramadol obtunded intra-operative sympathetic responses better than tramadol alone. …”
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Combined Neuroleptic Analgesia in Acute Coronary Heart Disease by O.V. Voennov, G.A. Boyarinov

“…The aim of investigation was opthimizaition an analgesia in patients with the acute forms of an ischemic heart, based on a combination of phentanyl, tramadol and droperidol. It proceeds from a comparative analysis of the investigating vales that a use of the phentanile-tramadole neuroleptanalgesia permits to more adequately conduct an analgesia, normalized the hemodynamics values, has better prognosis. …”
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Efficacy of Combination Therapy with Pregabalin in Neuropathic Pain: A Preclinical Study in the Rat L5 Spinal Nerve Ligation Model by Nozawa K, Karasawa Y, Shidahara Y, Ushida T

“…Pregabalin combined with tramadol may serve as a promising drug combination for the effective management of neuropathic pain.Keywords: analgesic, animal model, isobologram, synergistic effects…”
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Comparison of the efficacy of erector spinae plane block performed with different concentrations of bupivacaine on postoperative analgesia after mastectomy surgery: ramdomized, pro... by Başak Altıparmak, Melike Korkmaz Toker, Ali İhsan Uysal, Semra Gümüş Demirbilek

“…The main measurements were postoperative tramadol consumption; Numerical Rating Scale (NRS) scores 15, 30, and 60 min and 12 and 24 h postoperatively; and intraoperative fentanyl requirements. …”
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Meme Kanseri Cerrahisinde Gabapentin Uygulamasının Preoperatif Anksiyete ve Postoperatif Analjezi Üzerine Etkisi by Seda KİŞİ, Ersel GÜLEÇ, Mediha TÜRKTAN, Zehra HATİPOĞLU, Yasemin GÜNEŞ

“…Her iki gruba da postoperatif analjezi amacıyla operasyon bitiminden 30 dk önce 1mg/kg i.v. tramadol uygulanmıştır. Postoperatif ağrıyı değerlendirmek amacıyla postoperatif Vizüel Analog Skala değerleri ile total tramadol tüketimi değerlendirilmiştir. …”
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Comparison of suprainguinal approach with infrainguinal approach of fascia iliaca compartment block for postoperative analgesia by Kamya Bansal, Namrata Sharma, Mirley R Singh, Anubhav Sharma, Rajat Roy, Sunanda Sethi

“…Conclusion: Suprainguinal FICB has superior analgesic efficacy over infrainguinal FICB in terms of reduced pain intensity, reduced 24-h tramadol consumption and better patient satisfaction.…”
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Relative toxicity of analgesics commonly used for intentional self-poisoning: a study of case fatality based on fatal and non-fatal overdoses by Hawton, K, Ferrey, A, Casey, D, Wells, C, Fuller, A, Bankhead, C, Clements, C, Ness, J, Gunnell, D, Kapur, N, Geulayov, G

“…<br/><br/> <strong>Conclusions</strong> Dihydrocodeine and tramadol are particularly toxic in overdose and codeine is also relatively toxic. …”

Subcostal transversus abdominis plane block can improve analgesia after laparoscopic cholecystectomy by Vladimir Vrsajkov, Nedjica Mančić, Dunja Mihajlović, Suzana Tonković Milićević, Arsen Uvelin, Jelena Pantić Vrsajkov

“…First group received bilateral ultrasound guided subcostal transversus abdominis plane block with 20 mL of 0.33% bupivacaine per side before operation and tramadol 1 mg.kg−1 IV for pain breakthrough (≥6). Second group received after operation tramadol 1 mg.kg−1/6 h as standard hospital analgesia protocol. …”
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The analgesic efficacy of ultrasound-guided transversus abdominis plane block vs. local anesthetic infiltration technique in major gynecologic surgery: A randomized controlled tria... by Samina Ismail, Akbar A Mistry, Ali S Siddiqui, Aliya Aziz, Nadeem F Zuberi

“…Outcome measures were cumulative and rescue tramadol consumption, numerical rating score (NRS) for pain and side effects in post-anesthesia care unit (PACU) at 4, 8, 12 hours postoperatively. …”
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