Analgesic effects of ultrasound-guided fourquadrant transversus abdominis plane in patients with cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a prospective... by Jaegyok Song, Nayoung Choi, Minji Kang, Sung Mi Ji, Dong-wook Kim, Min A Kwon

“…Oxycodone in the post-anesthesia care unit (PACU) and pethidine or tramadol in the ward were used as rescue analgesics. …”
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Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study by Ángel Becerra-Bolaños, Miriam Jiménez-Gil, Mario Federico, Yurena Domínguez-Díaz, Lucía Valencia, Aurelio Rodríguez-Pérez

“…Continuous intravenous infusion of tramadol and metamizole made peri-procedural pain during HDR mild in most cases. …”
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High frequency transcutaneous electrical stimulation in the immediate postoperative period of anterior cruciate ligament reconstruction: a randomized clinical trial by Marcelo Baptista Dohnert, Nicole de Oliveira Cardoso Novaski, Juliana Ribeiro Deves, Albertino Rennan de Oliveira Soares, Marcelo Medeiros da Silveira, João Victor Euzébio dos Santos, Paulo Afonso Kuplich, Rodrigo Boff Daitx

“…When compared to the Control group (CG), the TENS group had a lower intake of ketoprofen (48.27%), diazepam (256.98%), and dipyrone (121.21%), morphine (320.77%), and tramadol (437.46%). Conclusion: Continuous high-frequency TENS significantly reduced pain intensity and significantly improved ROM, muscle strength, and drug intake in the postoperative period of ACL reconstruction. …”
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The Effect of Epidural Analgesia on Quality of Recovery (QoR) after Radical Prostatectomy by Ruben Kovač, Ivo Juginović, Nikola Delić, Ivan Velat, Hrvoje Vučemilović, Ivan Vuković, Verica Kozomara, Božidar Duplančić

“…The second (control) group received general anesthesia and continuous postoperative intravenous analgesia with tramadol. Both groups received multimodal analgesia with metamizole. …”
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The Efficacy of Erector Spinae Plane Block for Patients Undergoing Percutaneous Nephrolithotomy by Mehmet Uğur Bilgin, Zeki Tuncel Tekgül, Tansu Değirmenci

“…GCont consumed more tramadol postoperatively (262.5 mg vs. 75 mg, P < 0.001).Conclusion:We found that ESPB reduced intraoperative opioid consumption. …”
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Traditional chest drainage versus drainage by thoracotomy: a prospective randomized study by Thiago Gangi Bachichi, Luiz Eduardo Villaça Leão, João Alessio Juliano Perfeito, Andre Miotto, Caio Santos Holanda, Altair da Silva Costa Jr

“…The intercostal drainage group had mean length of hospital stay (p=0.527) and drainage (p=0.547) of 4 days, and the traditional chest drainage group and 2 and 5.5 days, respectively. Dipirona and tramadol doses did not differ between groups (p=0.201 and p=0.341). …”
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Adulterants present in the San Diego county fentanyl supply: a laboratory analysis of seized law enforcement samples by Henrik Galust, Justin A. Seltzer, Jeremy R. Hardin, Nathan A. Friedman, Jeff Salamat, Richard F. Clark, Jennifer Harmon

“…The most common adulterants included 4-methylaminoantipyrine (4-MAAP) (10.9%), mannitol (9%), acetaminophen (8.5%), methamphetamine (4.2%), diacetylmorphine (heroin) (3.6%), tramadol (1.9%), and xylazine (1.7%). Several additional pharmacologically active adulterants and contaminants of interest were also identified. …”
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Does Pain Following Laparoscopic Cholecystectomy Differ in Diabetics? by Sevim Baltalı, Bünyamin Gürbulak, Seda Seven, Hasan Ökmen

“…In the multivariable analysis, the group with diabetes was shown to be strongly related with a significantly lower dosage of tramadol consumption compared to the control group.Conclusion:According to our findings, the patient with diabetes who underwent LC experienced less postoperative discomfort than those without diabetes. …”
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Opioids and frequency counts in the US Food and Drug Administration Adverse Event Reporting System (FAERS) database: a quantitative view of the epidemic by Veronin MA, Schumaker RP, Dixit RR, Elath H

“…Drugs identified included: morphine, fentanyl, oxycodone, hydrocodone, tramadol, hydromorphone, methadone, codeine, oxymorphone, meperidine, propoxyphene, diphenoxylate, and heroin. …”
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Effects of Preoperative Pregabalin On Postoperative Pain Control in Total Knee Arthroplasty Surgery by Mutlu Akdoğan, Gülten Ütebey, Halis Atıl Atilla, Alper Öztürk, Mehmet Faruk Çatma

“…VAS scores at the postoperative 4th, 12th, and 48th hours, frequency of pushing the button of PCA system, and the total tramadol dose were significantly lower in the pregabalin group. …”
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Determination of Prenatal Substance Exposure Using Meconium and Orbitrap Mass Spectrometry by Atakan Hernandez, Valerie Lacroze, Natalia Doudka, Jenny Becam, Carole Pourriere-Fabiani, Bruno Lacarelle, Caroline Solas, Nicolas Fabresse

“…The application allows the detection of 88 substances, including 47 pharmaceuticals and 15 pharmaceutical metabolites, cocaine and its metabolites, THC and its metabolites, and natural (morphine, codeine) and synthetic (methadone, buprenorphine, tramadol, norfentanyl) opioids. This method is now used routinely for toxicological screening in high-risk pregnancies…”
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Use of Intraperitoneal and Port Site Infiltration of Bupivacaine for Controlling Pain after Laparoscopic Cholecystectomy: A Prospective Study by Ubaid Ali, Hanief Mohamed Dar, Mir Mujtaba Ahmad, Nazir Ahmed Salroo, Shah Touseef, Sheikh Imran

“…Total consumption of diclofenac in cases was 95mg whereas in controls it was 108.75mg (p=0.246), while as total consumption of tramadol in cases was 50 mg, whereas in controls it was 130mg (p<0.05). …”
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Efficacy of transversalis fascia plane block as a novel ındication for varicocelectomy surgery: prospective randomized controlled study by Erkan Cem Celik, Isa Ozbey, Muhammed Enes Aydin, Ahmet Murat Yayik, Elif Oral Ahiskalioglu, Ibrahim Hakki Tor, Ali Ahiskalioglu

“…At all hours, there was a statistically significant decrease in favor of Group TFPB in terms of active and passive VAS scores (p < 0.001), non steroidal anti-inflammatory analgesic use (p < 0.05), and tramadol requirement (p < 0.001). Conclusion This study has shown that TFPB can provide a more effective analgesia when compared to surgical site infiltration.…”
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International Comparison in Opiate Prescribing for New Users in Primary Care using Electronic Medical Record Data by Robyn Tamblyn, Nadyne Girard, Bettina Habib, William Dixon, Meghna Jani, David Bates, Jennifer Haas

“…In the U.S 65.0\% were started on oxycodone (MME:1.5), and 10.9% on hydrocodone (MME:1). In Canada, tramadol (18.2%; MME: 0.1) followed by oxycodone (13.2%) were the next most commonly prescribed drugs. …”
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Paracetamol Use in Patients With Osteoarthritis and Lower Back Pain: Infodemiology Study and Observational Analysis of Electronic Medical Record Data by Gisèle Pickering, Linda Mezouar, Hayet Kechemir, Caty Ebel-Bitoun

“…Paracetamol brands are frequently prescribed in France for musculoskeletal pain and include Doliprane, Dafalgan, and Ixprim (tramadol-paracetamol). ObjectiveThe objective of this retrospective study was to understand the journey of patients with LBP or OA when treated with paracetamol. …”
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Analgesic Prescription Patterns and Pain Outcomes in Southeast Asia: Findings From the Analgesic Treatment of Cancer Pain in Southeast Asia Study by Thinh, Dang Huy Quoc, Sriraj, Wimonrat, Mansor, Marzida, Tan, Kian Hian, Irawan, Cosphiadi, Kurnianda, Johan, Nguyen, Yen Phi, Ong-Cornel, Annielyn, Hadjiat, Yacine, Moon, Hanlim, Javier, Francis O.

“…The median daily dose prescribed in oral morphine equivalents was 30 mg for both morphine and tramadol. Conclusion: Despite unrelieved pain, sleep disturbance, and issues with quality of life, a notable proportion of patients were prescribed only weak opioids, and opioid doses prescribed were generally low. …”

Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators by Larisa H. Cavallari, Emily Cicali, Kristin Wiisanen, Roger B. Fillingim, Hrishikesh Chakraborty, Rachel A. Myers, Kathryn V. Blake, Bolanle Asiyanbola, Jordan F. Baye, Wesley H. Bronson, Kelsey J. Cook, Erica N. Elwood, Chancellor F. Gray, Yan Gong, Lindsay Hines, Joseph Kannry, Natalie Kucher, Sheryl Lynch, Khoa A. Nguyen, Aniwaa Owusu Obeng, Victoria M. Pratt, Hernan A. Prieto, Michelle Ramos, Azita Sadeghpour, Rajbir Singh, Marc Rosenman, Petr Starostik, Cameron D. Thomas, Emma Tillman, Paul R. Dexter, Carol R. Horowitz, Lori A. Orlando, Josh F. Peterson, Todd C. Skaar, Sara L. Van Driest, Simona Volpi, Deepak Voora, Hari K. Parvataneni, Julie A. Johnson, for the IGNITE Pragmatic Trials Network

“…Abstract Opioid prescribing for postoperative pain management is challenging because of inter‐patient variability in opioid response and concern about opioid addiction. Tramadol, hydrocodone, and codeine depend on the cytochrome P450 2D6 (CYP2D6) enzyme for formation of highly potent metabolites. …”
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Cryo-Compression Therapy After Elective Spinal Surgery for Pain Management: A Cross-Sectional Study With Historical Control by Vugar Nabi Nabıyev, Selim Ayhan, Prashant Adhıkarı, Engin Cetın, Selcuk Palaoglu, R. Emre Acaroglu

“…The cumulative mean analgesic consumption of paracetamol, tenoxicam, and tramadol in the DC group vs. control group was 3,733.3±562.7 mg vs. 4,633.3±693.5 mg (p<0.005), 53.3±19.5 mg vs. 85.3±33.4 mg (p<0.005), and 63.3±83.4 mg vs. 393.3±79.9 mg (p<0.0001), respectively. …”
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Republication of “Postoperative Narcotic Prescription Practice in Orthopedic Foot and Ankle Surgery” by Thomas M. Hearty MD, DPT, Paul Butler MD, John Anderson MD, Donald Bohay MD

“…Less experienced surgeons (less than 5 years in practice) supplement with tramadol more for scenario 1 ( P = .034) as well as use regional nerve blocks for scenario 2 ( P = .039) more than experienced surgeons (more than 15 years in practice). …”
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Acupuncture in the Anesthetic Recovery of Bitches Submitted to Ovariohysterectomy by Amanda Caroline Gomes Graboschii, Carolina Carvalho dos Santos Lira, Jackellyne Laís Ferreira Lins, Marcia Kikuyo Notomi, Pierre Barnabé Escodro

“…Methods : As pre-anesthetic protocol, acepromazine 0.2% (0.1 mg/kg) and tramadol hydrochloride (2 mg/kg) was used, and induction was performed using midazolam (0.5 mg/kg) and ketamine (10 mg/kg). …”
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