Lumbar Epidural Anaesthesia versus Caudal Epidural Anaesthesia- Intraoperative and Postoperative Profile in Paediatric Surgical Patients by Pareesa Rashid, Khairat Mohd Butt, Sargam Goel, Aamil Haameem, Showkat Ahmed Gurcoo

“…Pain was measured postoperatively using Face, Legs, Activity, Cry, Consolability (FLACC) score and number of rescue top ups in the form of tramadol 1.5 mg/kg epidurally were noted. Student’s independent-test was employed for intergroup and, paired t-test and Fisher’s-exact test was used for intragroup analysis. …”
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Assessing Patient Perceptions and Experiences of Paracetamol in France: Infodemiology Study Using Social Media Data Mining by Stéphane Schück, Avesta Roustamal, Anaïs Gedik, Paméla Voillot, Pierre Foulquié, Catherine Penfornis, Bernard Job

“…Doliprane was the most common medication mentioned (14,058/44,283, 31.74%) within the Aggregate group, and tramadol was the most commonly mentioned drug in combination with paracetamol in the Aggregate group (1038/19,587, 5.30%). …”
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Risco de quedas associado a terapia medicamentosa em pacientes hospitalizados by Vivian Lemes Lobo Bittencourt, Iara Denise Endruweit Battisti, Anieli Aparecida Petri, Christiane de Fátima Colet, Eniva Miladi Fernandes Stumm, Marli Maria Loro, Eliane Roseli Winkelmann

“…A interação grave mais frequente foi morfina e tramadol (7,7%). Evidenciou-se que fármacos frequentemente utilizados por pacientes hospitalizados estão associados ao risco elevado de quedas e que a existência de interações medicamentosas potenciais, que elevam o risco de quedas. …”
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Shivering control in women under spinal anesthesia: A narrative review on the role of drugs by Mehrdad Malekshoar, Majid Vatankhah, Athar Rasekh Jahromi, Hamed Ghasemloo, Farideh Mogharab, Mojtaba Ghaedi, Samaneh Abiri, Lohrasb Taheri, Davoud Roostaei, Navid Kalani, Naser Hatami, Seyed Ebrahim Sadeghi

“…Opioid drugs such as fentanyl, tramadol, and pethidine have also been reviewed in some studies.Conclusion: Based on various studies, pethidine with unknown and possible mechanism of μ receptors seems to be the best drug in control of Shivering in cesarean section.…”
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Ultrasound Guided versus Peripheral Nerve Stimulator Guided Transversus Abdominis Plane Block for Postoperative Analgesia in Patients undergoing Laparoscopic Cholecystectomy: A Ran... by Kapil Prajapati, Kuldeep Kumar Patel, Hansraj Baghel, Ravi Prakash, Alok Pratap Singh

“…The duration of analgesia was least in group 3 (5.8±2.31 hrs) followed by group 2 (9.67±2.47 hrs) and maximum in group 1 (11.87±2.97 hrs). The total tramadol requirement in first 24 hours postoperatively was 126.67±44.98 mg in group 1, 140±62.15 mg in group 2 and 226.67±63.97 mg in group 3. …”
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Implementation of a piritramide based patient-controlled analgesia (PCA) as a standard of care for pain control in late abortion induction: A prospective cohort study from a patien... by L. Tascón Padrón, N.L.A. Emrich, B. Strizek, A. Gass, C. Link, T. Hilbert, S. Klaschik, W. Meissner, U. Gembruch, J. Jiménez Cruz

“…Methods: Evaluation of pain management after implementation of a PCA system compared with previous nurse-controlled tramadol-based standard under routine conditions. Patients answered a validated pain questionnaire and requirement of rescue analgesics was assessed. …”
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The investigation of surrogate markers for post-market surveillance in primary total hip arthroplasty by Malak, TT

“…Patients in the top quintile of NSAID use had a sub-hazard ratio (SHR) of 2.20 [95%CI 1.35-3.59; p=0.002], patients using Tramadol SHR 2.42 [95%CI 1.74-3.35; p<0.001], those using atypical analgesics SHR 2.59 [95%CI 1.70-3.95; p<0.001], patients visiting their primary care physician more than four times had a SHR of 2.10 [95%CI 1.29-3.42; p=0.003], patients referred to the Orthopaedic department SHR 1.90 [95%CI 1.16-3.13; p=0.011], and those referred to the Physiotherapy department SHR 2.07 [95%CI 1.29-3.32; p=0.003].…”

Effect of Low Dose Intravenous Magnesium Sulphate on Sensory Regression Time in Patients undergoing Spinal Anaesthesia- A Randomised Placebo-controlled Double-blinded Study by Babita Lahkar, Vidyasagar V Reddy, Vikramjit Baruah, Priyam Saikia

“…The total consumption of tramadol in the group M was significantly lesser than the control group (192.5±58.03 mg and 245.0±43.74 mg, respectively, p=0.0002). …”
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THE EUROPEAN SOCIETY FOR CLINICAL AND ECONOMIC ASPECTS OF OSTEOPOROSIS AND OSTEOARTHRITIS (ESCEO) ALGORITHM FOR THE MANAGEMENT OF KNEE OSTEOARTHRITIS IS APPLICABLE TO RUSSIAN CLINI... by L. N. Denisov, E. S. Tsvetkova, G. Sh. Golubev, O. V. Bugrova, I. S. Dydykina, A. I. Dubikov, L. V. Menshikova, L. K. Peshekhonova, A. P. Rebrov, A. N. Torgashin, E. A. Trofimov, S. P. Yakupova, E. V. Zonova, O. Brewer, C. Cooper, J. Reginster, L. A. Knyazeva

“…As a last step before surgery, the slow titration of sustained-release tramadol, a weak opioid, affords sustained analgesia with improved tolerability.…”
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The Role of Ketamine as a Component of Multimodal Analgesia in Burns: A Retrospective Observational Study by Marina Stojanović, Milana Marinković, Biljana Miličić, Milan Stojičić, Marko Jović, Milan Jovanović, Jelena Isaković Subotić, Milana Jurišić, Miodrag Karamarković, Aleksandra Đekić, Kristina Radenović, Jovan Mihaljević, Ivan Radosavljević, Branko Suđecki, Milan Savić, Marko Kostić, Željko Garabinović, Jelena Jeremić

“…Contrarily, both groups of patients required postoperative tramadol treatment, while intraoperative ketamine administration had no beneficial effects on postoperative pain management.…”
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Analgesic Efficacy of Dexamethasone and Dexmedetomidine as an Adjuvant to 2% Lignocaine Adrenaline and 0.5% Bupivacaine in Transversus Abdominis Plane Block after Caesarean Deliver... by V Rao Yarramsetti, Sai Sravanthi Thumpati, Hari Kiran Varma Nadimpalli, LV Simhachalam Kutikuppala

“…The patients who received ultrasound-guided TAP block with dexmedetomidine were significantly less on-demand of tramadol (p-value=0.005). The patients who received ultrasound-guided TAP block with dexmedetomidine were had significantly lower VAS scores at 4 hours (p-value=0.002), 6 hours (p=0.001), and 12 hours (p=0.3), postoperatively. …”
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Effectivness of dexametasone vs. Magnesium sulphate in postoperative analgesia: Dexametasone vs. Magnesium sulphate by Dautaj Brikena, Bulku Esmerilda, Jaho Enriketa, Sturce Rexhina, Llazani Arvit, Zhurda Tefik, Jovičić Jelena, Gvozdić Branka

“…For pain control after surgery all patients received tramadol 0.9-1.2 mg/kg and diklophenac 1.76 mg/kg. …”
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Seizures of illicit substances for personal use in two Italian provinces: analysis of trends by type and purity from 2008 to 2017 by Patrizia Verri, Cecilia Rustichelli, Anna Ferrari, Filippo Marchesi, Carlo Baraldi, Manuela Licata, Daniele Vandelli, Federica Palazzoli, Francesco Potì, Enrico Silingardi

“…Especially from 2014, the range of seized substances increased and started to include synthetic cathinones, phenylethylamines, UR-144, LSD, psilocybe, prescription opioid and hypnotics. In two cases, tramadol together with tropicamide was seized. Most of the seizures involved male subjects and 82% of the seizures were from individuals younger than 35 years of age. …”
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Maternal and Perinatal Outcomes in Planned Labour: A Prospective Interventional Study by Khyati Gupta, Dolly Maravi, Priyadarshini Tiwari, Azra Khan, Raksha Singh, Bhoomija Rajpoot

“…The case group received a programmed labour regime, which involved administering small doses of various drugs such as pentazocine, drotaverine, diazepam, and tramadol. No analgesia was given to the control group. …”
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Efficacy of extended view totally extra peritoneal approach versus laparoscopic intraperitoneal on lay mesh plus for abdominal wall hernias: a single center preliminary retrospecti... by Haisong Xu, Wenhao Huang, Yuehua Guo, Mingyue Li, Gongze Peng, Tianchong Wu

“…Postoperative pain levels (VAS; visual analog scale) (4.2 ± 0.9 vs. 6.7 ± 0.9, P < 0.01), analgesic requirements (Tramadol) (25.0 ± 37.0 mg vs. 72.6 ± 40.5 mg, P < 0.01), length of hospital stay (1.2 ± 0.5days vs. 2.2 ± 0.6days, P < 0.01), and total hospitalization expenses (19695.9 ± 1221.7CNY vs. 35286.2 ± 1196.6CNY, P < 0.01) were significantly lower in the e-TEP group. …”
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Pain levels and patient comfort after lower limb arthroplasty comparing i.v. patient-controlled analgesia, continuous peripheral nerve block and neuraxial analgesia: a retrospectiv... by Alina Yurutkina, Sven Klaschik, Pascal Kowark, Annette Gass, Carolina Link, Thomas Martin Randau, Jorge Jiménez-Cruz, Mark Coburn, Tobias Hilbert

“…Patients undergoing THA received either continuous epidural ropivacaine infusion (0.133%, Epi) or patient-controlled analgesia (PCA) with the Wurzburg Pain Drip (tramadol, metamizole and droperidol, WPD) or with piritramide (Pir). …”
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Prevalence of exposure to pharmacogenetic drugs by the Saudis treated at the health care centers of the Ministry of National Guard by Mohammad A. Alshabeeb, Mesnad Alyabsi, Bien Paras

“…The analgesic group was the most prescribed drug category (47%), which included ibuprofen (20.5%), celecoxib (6.3%), tramadol (5.8%), and others. Cardiovascular agents were the second-most utilized drug class (24.4%). …”
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CYP2D6 Substrate Dispensing Among Patients Dispensed Mirabegron: An Administrative Claims Analysis by Mary E. Ritchey, Jingjun Wang, Jessica C. Young, Rajat Chandra, Adam Carrera, Noelia Goti, John R. Horn, Cynthia J. Girman

“…Commonly codispensed CYP2D6 substrates included hydrocodone, oxycodone, tramadol, metoprolol, and tamsulosin. Findings were similar for patients in the older cohort (≥ 65 years old), with 72.1% receiving overlapping CYP2D6 substrates. …”
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Opioid sparing effect of intravenous dexmedetomidine in orthopaedic surgery: a retrospective analysis by Valerio Donatiello, Aniello Alfieri, Andrea Napolitano, Vincenzo Maffei, Francesco Coppolino, Vincenzo Pota, Maria Beatrice Passavanti, Maria Caterina Pace, Pasquale Sansone

“…All patients received postoperative 24-h analgesia consisting of 60 mg of ketorolac, 200 mg of tramadol and 4 mg of ondansetron. The primary outcome measured how many patients in the two groups required an analgesic rescue dose of pethidine and the time to first pethidine administration. …”
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Direct anterior approach with conventional instruments versus robotic posterolateral approach in elective total hip replacement for primary osteoarthritis: a case–control study by Mattia Alessio-Mazzola, Pietro Colombo, Niccolo’ Barducci, Elena Ghezzi, Luigi Zagra, Patrizio Caldora, Marco Ometti, Giacomo Placella, Vincenzo Salini

“…Patients in the R-PL group required less rescue tramadol (p > 0.001), ketorolac (p = 0.028) and acetaminophen (p < 0.001). …”
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