Follow-up Study of a Child with Severe Combined Immune Deficiency by T. B. Pavlova, V. M. Shinkareva

“…According to the chimerism, immune transplant rejection was observed after 1.5 months. At 2 years 11 months, the boy successfully underwent allogeneic bone marrow transplantation from an unrelated donor in the Children’s Oncology and Hematology Hospital of the University Hospital Freiburg (Germany). …”
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Roles of Regulatory T Cell-Derived Extracellular Vesicles in Human Diseases by Can Lin, Jihua Guo, Rong Jia

“…The abnormal quantity or function of Treg-EVs is associated with several types of human diseases or conditions, such as transplant rejection, inflammatory diseases, autoimmune diseases, and cancers. …”
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Advances in the study of HLA class Ib in maternal-fetal immune tolerance by Yiran Yang, Wanning Wang, Jing Weng, Huifang Li, Yanmin Ma, Lingyan Liu, Wei Ma

“…The HLA class Ib molecule is an alloantigen that causes transplant rejection on behalf of individual human and plays an important role in maternal-fetal immune tolerance. …”
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A survey of extracorporeal photopheresis treatment in pediatric patients in the United Kingdom by Aisling M. Flinn, Sheba Macheka, Mary Slatter, Anna‐Maria Ewins, Brenda Gibson, Sarah Lawson, Anna Tailby, Giovanna Lucchini, Helen New, Beki James, Arun Alfred, Julia Scarisbrick, Andrew R Gennery

“…Abstract Extracorporeal photopheresis (ECP) is a second‐line therapy in acute and chronic GVHD and solid organ transplant rejection. We report ECP use in 98 pediatric patients in seven UK centers from 2010 to 2017, the majority treated for aGVHD (73.5%). …”
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Salivary and serum periostin in kidney transplant recipients. by Seyed Mohammad Kazem Aghamir, Mahrokh Amiri, Ghodratollah Panahi, Fatemeh Khatami, Sanaz Dehghani, Mahdieh-Sadat Moosavi

“…<h4>Introduction</h4>End-stage renal disease (ESRD) treatment includes dialysis and kidney transplantation. Transplant rejection is a major barrier to transplant success. …”
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Perioperative nursing of a child undergoing islet transplantation followed by kidney transplantation (儿童肾移植后胰岛移植1例的围手术期护理) by LUO Xinchun (罗新春), YE Haidan (叶海丹), CHEN Huilin (陈慧琳)

“…Key issues of postoperative nursing were prevention of portal thrombosis, blood glucose monitoring, prevention of transplant rejection and infection. (本文回顾1例儿童糖尿病合并肾功能衰竭肾移植术后行胰岛移植的临床资料, 总结围手术期护理措施。…”
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Methods of ex vivo analysis of tissue status in vascularized composite allografts by Carolyn Ton, Sara Salehi, Sara Abasi, John R. Aggas, Renee Liu, Gerald Brandacher, Anthony Guiseppi-Elie, Warren L. Grayson

“…However, the complex tissue composition of vascularized composite allografts (VCAs) presents unique clinical challenges that increase the likelihood of transplant rejection. Under prolonged static cold storage, highly damage-susceptible tissues such as muscle and nerve undergo irreversible degradation that may render allografts non-functional. …”
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Sustained release from biodegradable metallic matrix—The entrapment of drugs within iron by Barak Menagen, David Avnir

“…Two drugs have been successfully entrapped and released: chlorhexidine - an antiseptic drug, and rapamycin—used for avoiding transplant rejection. The delivery profiles of the composites were studied in two forms—powders and pressed discs showing two different types of drug release profiles. …”
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Regulatory B Cells—Immunopathological and Prognostic Potential in Humans by Johanna Veh, Carolin Ludwig, Hubert Schrezenmeier, Bernd Jahrsdörfer

“…Bregs play an important role in attenuating pathological inflammatory reactions that can be associated with transplant rejection, graft-versus-host disease, autoimmune diseases and allergies but also with infectious, neoplastic and metabolic diseases. …”
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Tolerogenic dendritic cell reporting: Has a minimum information model made a difference? by Ayesha Sahar, Ioana Nicorescu, Gabrielle Barran, Megan Paterson, Catharien M.U. Hilkens, Phillip Lord

“…In 2016, Minimum Information about Tolerogenic Antigen-Presenting cells (MITAP) was created to standardize the reporting on tolerogenic antigen-presenting cells, including tolerogenic dendritic cells (tolDCs). tolDCs is a generic term for dendritic cells that have the ability to (re-)establish immune tolerance; they have been developed as a cell therapy for autoimmune diseases or for the prevention of transplant rejection. Because protocols to generate these therapeutic cells vary widely, MITAP was deemed to be a pivotal reporting tool by and for the tolDC community. …”
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A survey on lymphocyte T CD3, CD4 and CD8 in peripheral blood of kidney transplant recipients using mycophenolic acid by Thi Mai Dung Do, Phan Hai An Ha, Van Dong Le, Quang Thuan Huynh

“…Conclusion: The T lymphocytes CD3, CD4 and CD8 in peripheral blood should be monitored at multiple post-transplant times to make early predictions of transplant rejection during follow-up treatment.…”
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Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats. by Daniel L Morgan, B Alex Merrick, Kevin E Gerrish, Patricia S Stockton, Yu Wang, Julie F Foley, William M Gwinn, Francine L Kelly, Scott M Palmer, Thai-Vu T Ton, Gordon P Flake

“…OB is most commonly associated with lung transplant rejection; however, OB has also been diagnosed in workers exposed to artificial butter flavoring (ABF) vapors. …”
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Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy. by Feng, G, Wood, K, Bushell, A

“… BACKGROUND: Regulatory T cells (Treg) play important roles in preventing autoimmunity, graft-versus host disease and transplant rejection. In rodent transplant models, tolerance induction strategies can induce graft protective CD25CD4 Treg in vivo but therapeutic exploitation of active regulation will more likely depend on protocols that allow generation or selection of regulatory cells ex vivo for use as a cellular therapy. …”

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. by Peto, R, Pike, M, Armitage, P, Breslow, N, Cox, DR, Howard, S, Mantel, N, McPherson, K, Peto, J, Smith, P

“…Both parts of this report are relevant to all clinical trials which study time to death, and wound be equally relevant to clinical trials which study time to other particular classes of untoward event: first stroke, perhaps, or first relapse, metastasis, disease recurrence, thrombosis, transplant rejection, or death from a particular cause. Part I, in this issue, collects together ideas that have mostly already appeared in the medical literature, but Part II, next month, is the first simple account yet published for non-statistical physicians of how to analyse efficiently data from clinical trials of survival duration. …”

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts by M. Eyad Khorki, M. Eyad Khorki, Tiffany Shi, Tiffany Shi, Tiffany Shi, Eileen E. Cianciolo, Ashley R. Burg, P. Chukwunalu Chukwuma, Jennifer L. Picarsic, Jennifer L. Picarsic, Mary K. Morrice, Mary K. Morrice, E. Steve Woodle, Jonathan S. Maltzman, Jonathan S. Maltzman, Autumn Ferguson, Jonathan D. Katz, Jonathan D. Katz, Brian M. Baker, David A. Hildeman, David A. Hildeman

“…IntroductionSignificant evidence suggests a connection between transplant rejection and the presence of high levels of pre-existing memory T cells. …”
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Is there a role for B lymphocyte chimerism in the monitoring of B-acute lymphoblastic leukemia patients receiving allogeneic stem cell transplantation? by Yi-Ning Yang, Xiao-Rui Wang, You-Wen Qin, Li-Ping Wan, Ying Jiang, Chun Wang

“…Objective: To determine the sensitivity and significance of B-cell chimerism for the detection of early engraftment, transplant rejection, and disease relapse. Methods: The dynamic monitoring of lineage-specific cell subtypes (B, T, and NK cells) was made in 20 B-cell acute lymphoblastic leukemia (B-ALL) patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). …”
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Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET. by Stefan Reuter, Uta Schnöckel, Rita Schröter, Otmar Schober, Hermann Pavenstädt, Michael Schäfers, Gert Gabriëls, Eberhard Schlatter

“…This method is potentially useful to improve post-transplant rejection monitoring.…”
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Comparison of single nucleotide polymorphisms and short tandem repeats as markers for differentiating between donors and recipients in solid organ transplantation by Hyun-Ji Lee, Kyoung-Hwa Shin, Su Jeong Jeong, In Suk Kim

“…Background : To analyze transplant rejection and to distinguish between donor and recipient, it is necessary to select a marker from single nucleotide polymorphism (SNP), short tandem repeat (STR), and human leukocyte antigen (HLA) testing. …”
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Histone Deacetylation Inhibitors as Modulators of Regulatory T Cells by Andreas von Knethen, Ulrike Heinicke, Andreas Weigert, Kai Zacharowski, Bernhard Brüne

“…The malfunction of CD4⁺ T_regs is associated with autoimmune responses such as rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1D), inflammatory bowel diseases (IBD), psoriasis, systemic lupus erythematosus (SLE), and transplant rejection. Recent evidence supports an opposed role in sepsis. …”
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Recent highlights in the immunomodulatory aspects of Treg cell-derived extracellular vesicles: special emphasis on autoimmune diseases and transplantation by Yahya Asemani, Sajad Najafi, Fatemeh Ezzatifar, Naime Majidi Zolbanin, Reza Jafari

“…These properties have resulted in the use of Treg-derived EVs' immunomodulatory effects moving beyond laboratory research and into preclinical applications in animal models of a variety of inflammatory, autoimmune, and transplant rejection disorders. However, insufficient evidence has been produced to permit enrollment in human clinical studies. …”
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