Effects of intravenous administration of peripheral blood‐derived mesenchymal stromal cells after infusion of lipopolysaccharide in horses by Sandra D. Taylor, Priscila B. S. Serpa, Andrea P. Santos, Kelsey A. Hart, Sarah A. Vaughn, George E. Moore, Abhijit Mukhopadhyay, Allen E. Page

“…Methods A randomized placebo‐controlled experimental trial was performed. Sixteen healthy horses were assigned to 1 of 2 treatment groups (1 × 109 PB‐MSC or saline placebo). …”
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Can sexual health interventions make community-based health systems more responsive to adolescents? A realist informed study in rural Zambia by Chama Mulubwa, Anna-Karin Hurtig, Joseph Mumba Zulu, Charles Michelo, Ingvild Fossgard Sandøy, Isabel Goicolea

“…We nested the study in the full intervention arm of the Research Initiative to Support the Empowerment of Girls trial in Zambia. Sixteen in-depth interviews were conducted with stakeholders involved in the development and/or implementation of the trial. …”
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Effects of a whole food diet on immune function and inflammatory phenotype in healthy dogs: A randomized, open-labeled, cross-over clinical trial by Jared A. Jaffey, Dan Su, Ross Monasky, Brenna Hanratty, Elizabeth Flannery, Melissa Horman

“…A prospective, randomized, open-labeled, cross-over clinical trial was performed. Sixteen healthy client-owned dogs were fed either a whole food or an extruded dry diet, and after 67 days, they were fed the alternate diet for an additional 67 days. …”
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Identifying Fatigue Indicators Using Gait Variability Measures: A Longitudinal Study on Elderly Brisk Walking by Guoxin Zhang, Ivy Kwan-Kei Wong, Tony Lin-Wei Chen, Tommy Tung-Ho Hong, Duo Wai-Chi Wong, Yinghu Peng, Fei Yan, Yan Wang, Qitao Tan, Ming Zhang

“…Nine sets of signals, including the accelerations, angular velocities, and rotation angles of the heel in three anatomical axes, were measured and extracted at the three walking times (baseline, 30th min, and 60th min) of the trial for analysis. Sixteen of eighteen participants reported fatigue after walking, and there were significant differences in the median acceleration (<i>p</i> = 0.001), variability of angular velocity (<i>p</i> = 0.025), and range of angle rotation (<i>p</i> = 0.0011), in the medial–lateral direction. …”
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High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trialResearch in context by Sandra D. Cassard, Kathryn C. Fitzgerald, Peiqing Qian, Susan A. Emrich, Christina J. Azevedo, Andrew D. Goodman, Elizabeth A. Sugar, Daniel Pelletier, Emmanuelle Waubant, Ellen M. Mowry

“…Methods: VIDAMS is a randomised, phase 3, double-blind, multi-centre, controlled trial conducted at sixteen neurology clinics in the United States. …”
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Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis by Alberto Ferrari, Alessandra Carobbio, Arianna Masciulli, Arianna Ghirardi, Guido Finazzi, Valerio De Stefano, Alessandro Maria Vannucchi, Tiziano Barbui

“…We searched for relevant articles or abstracts in the following databases: Medline, EMBASE, clinicaltrials.gov, WHO International Clinical Trials Registry, LILACS. Sixteen studies published from 2008 to 2018 reporting number of events using World Health Organization diagnosis for polycythemia vera were selected. …”
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Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series by Leo R. Brown, Mariana S. Sousa, Michael S. Yule, Vickie E. Baracos, Donald C. McMillan, Jann Arends, Trude R. Balstad, Asta Bye, Olav Dajani, Ross D. Dolan, Marie T. Fallon, Christine Greil, Marianne J. Hjermstad, Gunnhild Jakobsen, Matthew Maddocks, James McDonald, Inger O. Ottestad, Iain Phillips, Judith Sayers, Melanie R. Simpson, Ola M. Vagnildhaug, Tora S. Solheim, Barry J.A. Laird, Richard J.E. Skipworth, the Cancer Cachexia Endpoints Working Group

“…The most frequently reported endpoints were assessments of body weight (68 trials, n = 11 561) followed by bioimpedance analysis (BIA)‐based estimates (23 trials, n = 3140). Sixteen trials (n = 3052) included dual‐energy X‐ray absorptiometry (DEXA)‐based endpoints, and computed tomography (CT) body composition was included in eight trials (n = 841). …”
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