Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin by Elia Moreno Cubero, Ane Ogbe, Isabela Pedroza-Pacheco, Myron S. Cohen, Barton F. Haynes, Persephone Borrow, Dimitra Peppa, Dimitra Peppa

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Stereotactic ablative radiotherapy (SABR) as primary, adjuvant, consolidation and re-treatment option in pancreatic cancer: scope for dose escalation and lessons for toxicity by Christy Goldsmith, P. Nicholas Plowman, Melanie M. Green, Roger G. Dale, Patricia M. Price

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Catatonia Psychopathology and Phenomenology in a Large Dataset by Eleanor Dawkins, Leola Cruden-Smith, Ben Carter, Ali Amad, Ali Amad, Michael S. Zandi, Michael S. Zandi, Glyn Lewis, Anthony S. David, Jonathan P. Rogers, Jonathan P. Rogers

“…This study aimed to use a large dataset to describe the clinical signs of catatonia; to assess whether these signs are associated with underlying diagnosis and prognosis; and to describe the phenomenology of catatonia, particularly with reference to fear.MethodsA retrospective descriptive cross-sectional study was conducted using the electronic healthcare records of a large secondary mental health trust in London, United Kingdom. Patients with catatonia were identified in a previous study by screening records using natural language processing followed by manual validation. …”
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Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1 by Silvia Dibenedetto, Maria Niklison-Chirou, Claudia P. Cabrera, Matthew Ellis, Lesley G. Robson, Paul Knopp, Francesco Saverio Tedesco, Martina Ragazzi, Valentina Di Foggia, Michael R. Barnes, Aleksandar Radunovic, Silvia Marino

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Perspectives of healthcare professionals and older patients on shared decision-making for treatment escalation planning in the acute hospital setting: a systematic review and quali... by Bronwen E. Warner, Adam Lound, Kate Grailey, Cecilia Vindrola-Padros, Mary Wells, Stephen J. Brett

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Antibiotic Class and Outcome in Post-stroke Infections: An Individual Participant Data Pooled Analysis of VISTA-Acute by Craig J. Smith, Craig J. Smith, Calvin Heal, Andy Vail, Adam R. Jeans, Willeke F. Westendorp, Paul J. Nederkoorn, Diederik van de Beek, Lalit Kalra, Joan Montaner, Joan Montaner, Mark Woodhead, Andreas Meisel

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A randomised controlled trial to investigate the clinical effectiveness and cost effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for depressed non-responders to Increas... by Thorsten Barnhofer, Barnaby D. Dunn, Clara Strauss, Florian Ruths, Barbara Barrett, Mary Ryan, Asha Ladwa, Frances Stafford, Roberta Fichera, Hannah Baber, Ailis McGuinness, Isabella Metcalfe, Delilah Harding, Sarah Walker, Poushali Ganguli, Shelley Rhodes, Allan Young, Fiona Warren

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Availability, scope and quality of monkeypox clinical management guidelines globally: a systematic review by Helen Groves, Dania Dahmash, Shevin T Jacob, Peter W Horby, Louise Sigfrid, Andrew Dagens, Erhui Cai, Ishmeala Rigby, Tom Fletcher, Lucille Blumberg, Alice Norton, Muge Cevik, Keerti Gedela, Melina Michelen, Vincent Cheng, Eli Harriss, Eika Webb, Amanda M Rojek, Susan Khader, Samuel Lipworth, Robert Nartowski, Peter Hart

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P1141: IBRUTINIB AND RITUXIMAB AS FIRST LINE THERAPY FOR MANTLE CELL LYMPHOMA: A MULTICENTRE, REAL-WORLD UK STUDY by A. Tivey, R. Shotton, T. A. Eyre, D. Lewis, N. Crosbie, E. Nga, R. Guerrero Camacho, W. Swe, H. Marr, C. Rees, S. Moule, T. Sutton, D. Wrench, N. Thomas, M. Wilson, J. Bailey, M. Prahladan, A. Hodson, M. Koppana, S. Smith, S. Jones, F. Miall, J. Norman, E. Davies, C. Hildyard, L. Lowry, S. Paneesha, I. Qureshi, A. Beech, C. Bedford, A. Everden, D. Tucker, J. Wright, J. Goddard, T. Nicholson, J. Wilson, A. Lord, B. Jackson, M. Flont, A. Gibb, K. Linton

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Assertive outreach treatment versus care as usual for the treatment of high-need, high-cost alcohol related frequent attenders: study protocol for a randomised controlled trial by R. Blackwood, A. Wolstenholme, A. Kimergård, S. Fincham-Campbell, Z. Khadjesari, S. Coulton, S. Byford, P. Deluca, S. Jennings, E. Currell, J. Dunne, J. O’Toole, J. Winnington, E. Finch, C. Drummond

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Subspecialisation in Emergency Radiology: Proposal for a harmonised European curriculum by Wagner, M. G., Fischer, M. R., Scaglione, M., Linsenmaier, U., Schueller, G., Berger, F. H., Dick, E., Basilico, R., Stajgis, M., Calli, C., Vaidya, S., Wirth, Stefan

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European standard clinical practice recommendations for children and adolescents with primary and recurrent osteosarcoma by Roelof van Ewijk, Nikolas Herold, Fredrik Baecklund, Daniel Baumhoer, Kjetil Boye, Nathalie Gaspar, Semi B. Harrabi, Lianne M. Haveman, Stefanie Hecker-Nolting, Laura Hiemcke-Jiwa, Valentine Martin, Cristina Mata Fernández, Emanuela Palmerini, Michiel A.J. van de Sande, Sandra J. Strauss, Stefan S. Bielack, Leo Kager

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Bictegravir/emtricitabine/tenofovir alafenamide as initial treatment for HIV-1: five-year follow-up from two randomized trialsResearch in context by Paul E. Sax, José R. Arribas, Chloe Orkin, Adriano Lazzarin, Anton Pozniak, Edwin DeJesus, Franco Maggiolo, Hans-Jürgen Stellbrink, Yazdan Yazdanpanah, Rima Acosta, Hailin Huang, Jason T. Hindman, Hal Martin, Jared M. Baeten, David Wohl

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The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients—The ExeRTiOn2 Trial by Ellen M. Castle, Ellen M. Castle, Ellen M. Castle, Giulia Dijk, Elham Asgari, Sapna Shah, Sapna Shah, Rachel Phillips, Rachel Phillips, James Greenwood, Kate Bramham, Kate Bramham, Joseph Chilcot, Sharlene A. Greenwood, Sharlene A. Greenwood, Sharlene A. Greenwood

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EMBIO trial study protocol: left gastric artery embolisation for weight loss in patients living with obesity with a BMI 35–50 kg/m2 by Francesca Fiorentino, Prashant Patel, Robert Thomas, Nicholas Andrew Johnson, Christina Gabriele Prechtl, Claire Smith, Ahmed R Ahmed, Elli Bourmpaki, Clifford R Weiss, Stephen Bloom, Tricia Tan, Toby Richards, Mohamad Hamady, Julian Hague, Jowad Raja, Thiagarajah Sasikaran, Richard Hesketh

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Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria [version 2; peer review: 2 approved] by Delphine Thizy, Lea Pare Toe, Charles Mbogo, Damaris Matoke-Muhia, Vincent Pius Alibu, S. Kathleen Barnhill-Dilling, Tracey Chantler, Gershom Chongwe, Jason Delborne, Lydia Kapiriri, Esther Nassonko Kavuma, Sethlomo Koloi-Keaikitse, Ana Kormos, Katherine Littler, Dickson Lwetoijera, Roberta Vargas de Moraes, Noni Mumba, Lilian Mutengu, Sylvia Mwichuli, Silvia Elizabeth Nabukenya, Janet Nakigudde, Paul Ndebele, Carolyne Ngara, Eric Ochomo, Simon Odiwuor Ondiek, Stephany Rivera, Aaron J. Roberts, Benjamin Robinson, Rodrick Sambakunsi, Abha Saxena, Naima Sykes, Brian B. Tarimo, Nicki Tiffin, Karen H. Tountas

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Management of Fibroblast Growth Factor Inhibitor Treatment–emergent Adverse Events of Interest in Patients with Locally Advanced or Metastatic Urothelial Carcinoma by Arlene O. Siefker-Radtke, Andrea Necchi, Se Hoon Park, Jesús García-Donas, Robert A. Huddart, Earle F. Burgess, Mark T. Fleming, Arash Rezazadeh Kalebasty, Begoña Mellado, Sergei Varlamov, Monika Joshi, Ignacio Duran, Scott T. Tagawa, Yousef Zakharia, Keqin Qi, Sydney Akapame, Spyros Triantos, Anne O'Hagan, Yohann Loriot

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Brain-age is associated with progression to dementia in memory clinic patients by Francesca Biondo, Amelia Jewell, Megan Pritchard, Dag Aarsland, Claire J. Steves, Christoph Mueller, James H. Cole

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CLEAR – clozapine in early psychosis: study protocol for a multi-centre, randomised controlled trial of clozapine vs other antipsychotics for young people with treatment resistant... by C. Casetta, P. Santosh, R. Bayley, J. Bisson, S. Byford, C. Dixon, R. J. Drake, R. Elvins, R. Emsley, N. Fung, D. Hayes, O. Howes, A. James, K. James, R. Jones, H. Killaspy, B. Lennox, L. Marchant, P. McGuire, E. Oloyede, M. Rogdaki, R. Upthegrove, J. Walters, A. Egerton, J. H. MacCabe

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False-negative RT-PCR for COVID-19 and a diagnostic risk score: a retrospective cohort study among patients admitted to hospital by Ashley Whittington, Ankur Gupta-Wright, Colin Kenneth Macleod, Sarah Ann Filson, Tumena Corrah, Victoria Parris, Miriam Harris, Rachel Tennant, Nidhi Vaid, Junko Takata, Sai Duraisingham, Nemi Gandy, Harmeet Chana, Alastair McGregor, Padmasayee Papineni

“…Objective To describe the characteristics and outcomes of patients with a clinical diagnosis of COVID-19 and false-negative SARS-CoV-2 reverse transcription-PCR (RT-PCR), and develop and internally validate a diagnostic risk score to predict risk of COVID-19 (including RT-PCR-negative COVID-19) among medical admissions.Design Retrospective cohort study.Setting Two hospitals within an acute NHS Trust in London, UK.Participants All patients admitted to medical wards between 2 March and 3 May 2020.Outcomes Main outcomes were diagnosis of COVID-19, SARS-CoV-2 RT-PCR results, sensitivity of SARS-CoV-2 RT-PCR and mortality during hospital admission. …”
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