Semi-supervised analysis of myeloid and T cell behavior in ex vivo ovarian tumor slices reveals changes in cell motility after treatments by Florian Laforêts, Panoraia Kotantaki, Beatrice Malacrida, Samar Elorbany, Ranjit Manchanda, Emmanuel Donnadieu, Frances Balkwill

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Near-infrared quantum dots for HER2 localization and imaging of cancer cells by Rizvi SB, Rouhi S, Taniguchi S, Yang SY, Green M, Keshtgar M, Seifalian AM

“…Sarwat B Rizvi,1 Sepideh Rouhi,1 Shohei Taniguchi,2 Shi Yu Yang,1 Mark Green,2 Mo Keshtgar,1,3 Alexander M Seifalian1,3 1UCL Centre for Nanotechnology and Regenerative Medicine, University College London, 2Department of Physics, King's College London, 3Royal Free London NHS Foundation Trust Hospital, London, UK Background: Quantum dots are fluorescent nanoparticles with unique photophysical properties that allow them to be used as diagnostic, therapeutic, and theranostic agents, particularly in medical and surgical oncology. …”
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Myocardial bioenergetic abnormalities in experimental uremia by Chesser AMS, Harwood SM, Raftery MJ, Yaqoob MM

“…Alistair MS Chesser,1 Steven M Harwood,2 Martin J Raftery,1 Muhammad M Yaqoob1,2 1Department of Nephrology, Barts Health NHS Trust, Royal London Hospital, 2Translational Medicine and Therapeutics, William Harvey Research Institute, John Vane Science Centre, Queen Mary University of London, London, UK Purpose: Cardiac bioenergetics are known to be abnormal in experimental uremia as exemplified by a reduced phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio. …”
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Implementation evaluation of staff support and wellbeing programmes at an academic health science centre during COVID-19: study protocol by Barbora Krausova, Sam Nishanth Gnanapragasam, Len Demetriou, Alison Beck, Renata Pires-Yfantouda, Mary Jane Docherty, Nick Sevdalis

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Biomaterials for corneal endothelial cell culture and tissue engineering by Mohit Parekh, Vito Romano, Kareem Hassanin, Valeria Testa, Rintra Wongvisavavit, Stefano Ferrari, Atikah Haneef, Colin Willoughby, Diego Ponzin, Vishal Jhanji, Namrata Sharma, Julie Daniels, Stephen B Kaye, Sajjad Ahmad, Hannah J Levis

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An implementation framework and a feasibility evaluation of a clinical decision support system for diabetes management in secondary mental healthcare using CogStack by Dipen Patel, Yamiko J Msosa, Tao Wang, Omar G Mustafa, Siobhan Gee, Julie Williams, Angus Roberts, Richard JB Dobson, Fiona Gaughran

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Reflections, impact and recommendations of a co-produced ecological momentary assessment (EMA) study with young people who have experience of suicidality and psychiatric inpatient... by L. Dewa, S. Pappa, L. Mitchell, M. Hadley, J. Cooke, P. Aylin

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Evaluating the dynamics of hospital COVID-19 contacts and subsequent conversion to SARS-CoV-2 infection: a multi-centre retrospective cohort study by Nneoma Okeke, Luke B. Snell, Balram Rathish, Amal Hussein, William Newsholme, Damien Mack, Aodhan Breathnach, Jonathan A. Otter

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Can head louse repellents really work? Field studies of piperonal 2% spray by Ian F. Burgess, Christine M. Brown, Nazma A. Burgess, Judith Kaufman

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The Role of FBXW7 in Gynecologic Malignancies by Riccardo Di Fiore, Sherif Suleiman, Rosa Drago-Ferrante, Yashwanth Subbannayya, Sarah Suleiman, Mariela Vasileva-Slaveva, Angel Yordanov, Francesca Pentimalli, Antonio Giordano, Jean Calleja-Agius

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The organization and impacts of clinical research delivery workforce redeployment during the COVID-19 pandemic: a qualitative case study of one research-intensive acute hospital tr... by Rachel Faulkner-Gurstein, David Wyatt, Hannah Cowan, Naomi Hare, Clair Harris, Charles Wolfe

“…In this paper we discuss the redeployment of the clinical research workforce to support the pandemic clinical services, detailing the process of organizing this redeployment, as well as the impacts redeployment has had on both staff and research delivery at one research-intensive acute NHS trust in London. Methods A social science case study of one large research-active NHS trust drawing on data from an online questionnaire; participant observation of key research planning meetings; semi-structured interviews with staff involved in research; and document analysis of emails and official national and trust communications. …”
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Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal As... by D. Banerjee, P. Winocour, T. A. Chowdhury, P. De, M. Wahba, R. Montero, D. Fogarty, A. H. Frankel, J. Karalliedde, P. B. Mark, D. C. Patel, A. Pokrajac, A. Sharif, S. Zac-Varghese, S. Bain, I. Dasgupta, On behalf of the Association of British Clinical Diabetologists and The Renal Association

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Exploring the working environment of Hospital Managers: a mixed methods study investigating stress, stereotypes, psychological safety and individual resilience by Grailey, K, Leon-Villapalos, C, Murray, E, J Brett, S

“…Participants were purposively recruited from all levels of hospital management within one National Health Service Trust in London, United Kingdom. An exploration of managers experiences was undertaken using semi-structured qualitative interviews. …”

Development of national consensus statements on food labelling interpretation and protein allocation in a low phenylalanine diet for PKU by British Inherited Metabolic Diseases Group (BIMDG) Dietitians Group, Sharon Evans, Suzanne Ford, Sarah Adam, Sandra Adams, Jane Ash, Catherine Ashmore, Gillian Caine, Rachel Carruthers, Sarah Cawtherley, Satnam Chahal, Anne Clark, Barbara Cochrane, Anne Daly, Karen Dines, Marjorie Dixon, Carolyn Dunlop, Charlotte Ellerton, Moira French, Lisa Gaff, Cerys Gingell, Diane Green, Joanna Gribben, Anne Grimsley, Paula Hallam, Una Hendroff, Melanie Hill, Rachel Hoban, Sarah Howe, Inderdip Hunjan, Kit Kaalund, Eimear Kelleher, Farzana Khan, Steve Kitchen, Karen Lang, Sharan Lowry, Jo Males, Georgina Martin, Nicola McStravick, Avril Micciche, Camille Newby, Claire Nicol, Rachel Pereira, Louise Robertson, Kathleen Ross, Emma Simpson, Kath Singleton, Rachel Skeath, Jacqueline Stafford, Allyson Terry, Ruth Thom, Alison Tooke, Karen vanWyk, Fiona White, Lucy White, Anita MacDonald

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Echocardiographic assessment of pulmonary hypertension: a guideline protocol from the British Society of Echocardiography by Daniel X Augustine , Lindsay D Coates-Bradshaw, James Willis, Allan Harkness, Liam Ring, Julia Grapsa, Gerry Coghlan, Nikki Kaye, David Oxborough, Shaun Robinson, Julie Sandoval, Bushra S Rana, Anjana Siva, Petros Nihoyannopoulos, Luke S Howard, Kevin Fox, Sanjeev Bhattacharyya, Vishal Sharma, Richard P Steeds, Thomas Mathew

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Exploring the working environment of Hospital Managers: a mixed methods study investigating stress, stereotypes, psychological safety and individual resilience by Kate Grailey, Clare Leon-Villapalos, Eleanor Murray, Stephen J Brett

“…Participants were purposively recruited from all levels of hospital management within one National Health Service Trust in London, United Kingdom. An exploration of managers experiences was undertaken using semi-structured qualitative interviews. …”
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First hospital outbreak of the globally emerging Candida auris in a European hospital by Silke Schelenz, Ferry Hagen, Johanna L. Rhodes, Alireza Abdolrasouli, Anuradha Chowdhary, Anne Hall, Lisa Ryan, Joanne Shackleton, Richard Trimlett, Jacques F. Meis, Darius Armstrong-James, Matthew C. Fisher

“…Results This report describes an ongoing outbreak of 50 C. auris cases over the first 16 month (April 2015 to July 2016) within a single Hospital Trust in London. A total of 44 % (n = 22/50) patients developed possible or proven C. auris infection with a candidaemia rate of 18 % (n = 9/50). …”
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Global health education in U.K. universities by Adrienne Lee, Matthew Quinn

“…Just 12 (44%) universities had registered sustainable partnerships with Tropical Health and Education Trust. The London School of Hygiene and Tropical Medicine was identified as the top deliverer of GHE, with the Universities of Leicester and the Universities of Exeter joint bottom. …”
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Functionalization of single-walled carbon nanotubes and their binding to cancer cells by Madani SY, Tan A, Dwek M, Seifalian AM

“…Seyed Yazdan Madani1, Aaron Tan1, Miriam Dwek2, Alexander M Seifalian1,31UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK; 2Department of Molecular and Applied Biosciences, School of Life Sciences, University of Westminster, London, UK; 3Royal Free Hampstead NHS Trust Hospital, London, UKBackground: Single-walled carbon nanotubes (SWCNTs) have novel properties including their nanoscale size and ease of cellular uptake. …”
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Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer’s disease: study protocol for a randomised controlled trial (ELAD study) by Grazia Daniela Femminella, Eleni Frangou, Sharon B. Love, Gail Busza, Clive Holmes, Craig Ritchie, Robert Lawrence, Brady McFarlane, George Tadros, Basil H. Ridha, Carol Bannister, Zuzana Walker, Hilary Archer, Elizabeth Coulthard, Ben R. Underwood, Aparna Prasanna, Paul Koranteng, Salman Karim, Kehinde Junaid, Bernadette McGuinness, Ramin Nilforooshan, Ajay Macharouthu, Andrew Donaldson, Simon Thacker, Gregor Russell, Naghma Malik, Vandana Mate, Lucy Knight, Sajeev Kshemendran, John Harrison, Christian Hölscher, David J. Brooks, Anthony Peter Passmore, Clive Ballard, Paul Edison

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