Showing 221 - 240 results of 6,614 for search '"Trypanosoma"', query time: 0.21s Refine Results
  1. 221

    Meiotic sex in Chagas disease parasite Trypanosoma cruzi by Philipp Schwabl, Hideo Imamura, Frederik Van den Broeck, Jaime A. Costales, Jalil Maiguashca-Sánchez, Michael A. Miles, Bjorn Andersson, Mario J. Grijalva, Martin S. Llewellyn

    Published 2019-09-01
    “…Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi, the causative agent of Chagas disease. …”
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    Transsulfuration is an active pathway for cysteine biosynthesis in Trypanosoma rangeli by Ibeth Romero, Jair Téllez, Lais Eiko Yamanaka, Mario Steindel, Alvaro José Romanha, Edmundo Carlos Grisard

    Published 2014-04-01
    “…Methods We cloned and characterised genes coding for a cystathionine β-synthase (CβS) and cysteine synthase (CS), key enzymes of the transsulfuration and assimilatory pathways, respectively, from the hemoflagellate protozoan parasite Trypanosoma rangeli. Results Our results show that T. rangeli CβS (TrCβS), similar to its homologs in T. cruzi, contains the catalytic domain essential for enzymatic activity. …”
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  10. 230

    Exosome secretion affects social motility in Trypanosoma brucei. by Dror Eliaz, Sriram Kannan, Hadassa Shaked, Gil Arvatz, Itai Dov Tkacz, Lior Binder, Hiba Waldman Ben-Asher, Uthman Okalang, Vaibhav Chikne, Smadar Cohen-Chalamish, Shulamit Michaeli

    Published 2017-03-01
    “…Here, we demonstrate that in the protozoan parasite Trypanosoma brucei, exosome secretion is induced by stress that affects trans-splicing. …”
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  11. 231

    Fexinidazole interferes with the growth and structural organization of Trypanosoma cruzi by Aline Araujo Zuma, Wanderley de Souza

    Published 2022-11-01
    “…Its effectiveness against Trypanosoma brucei encouraged the investigation of its antiparasitic potential against T. cruzi, the aetiological agent of Chagas disease. …”
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    Ancestral genomes, sex, and the population structure of Trypanosoma cruzi. by Jorge M de Freitas, Luiz Augusto-Pinto, Juliana R Pimenta, Luciana Bastos-Rodrigues, Vanessa F Gonçalves, Santuza M R Teixeira, Egler Chiari, Angela C V Junqueira, Octavio Fernandes, Andréa M Macedo, Carlos Renato Machado, Sérgio D J Pena

    Published 2006-03-01
    “…Acquisition of detailed knowledge of the structure and evolution of Trypanosoma cruzi populations is essential for control of Chagas disease. …”
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    Unusual features and localization of the membrane kinome of Trypanosoma brucei. by Bryan C Jensen, Pashmi Vaney, John Flaspohler, Isabelle Coppens, Marilyn Parsons

    Published 2021-01-01
    “…In contrast, our search of the Trypanosoma brucei kinome showed that there were only ten protein kinases with predicted transmembrane domains, and unlike other eukaryotic transmembrane kinases, seven are predicted to bear multiple transmembrane domains. …”
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  17. 237

    Acidocalcisome-Mitochondrion Membrane Contact Sites in Trypanosoma brucei by Srinivasan Ramakrishnan, Beejan Asady, Roberto Docampo

    Published 2018-03-01
    “…Here, we investigated the presence of such contact sites in Trypanosoma brucei. In mammalian cells, endoplasmic reticulum-mitochondria contact sites facilitate mitochondrial uptake of Ca2+ released by the ER-located inositol 1,4,5-trisphosphate receptor (InsP3R). …”
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    MIF contributes to Trypanosoma brucei associated immunopathogenicity development. by Benoît Stijlemans, Lin Leng, Lea Brys, Amanda Sparkes, Liese Vansintjan, Guy Caljon, Geert Raes, Jan Van Den Abbeele, Jo A Van Ginderachter, Alain Beschin, Richard Bucala, Patrick De Baetselier

    Published 2014-09-01
    “…Using MIF-deficient mice and anti-MIF antibody treated mice, we show that MIF mediates the pathogenic inflammatory immune response and increases the recruitment of inflammatory monocytes and neutrophils to contribute to liver injury in Trypanosoma brucei infected mice. Moreover, neutrophil-derived MIF contributed more significantly than monocyte-derived MIF to increased pathogenic liver TNF production and liver injury during trypanosome infection. …”
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