Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium by Kayla M. Gross, Wenhui Zhou, Jerrica L. Breindel, Jian Ouyang, Dexter X. Jin, Ethan S. Sokol, Piyush B. Gupta, Kathryn Huber, Lee Zou, Charlotte Kuperwasser

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Venetoclax induces deep hematologic remissions in t(11;14) relapsed/refractory AL amyloidosis by Vikram J. Premkumar, Suzanne Lentzsch, Samuel Pan, Divaya Bhutani, Joshua Richter, Sundar Jagannath, Michaela Liedtke, Arnaud Jaccard, Ashutosh D. Wechalekar, Raymond Comenzo, Vaishali Sanchorawala, Bruno Royer, Michael Rosenzweig, Jason Valent, Stefan Schönland, Rafael Fonseca, Sandy Wong, Prashant Kapoor

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Chronic Kidney Disease Progression and Cardiovascular Outcomes Following Cardiac Catheterization—A Population‐Controlled Study by Jeremiah R. Brown, Richard J. Solomon, R. Brooks Robey, Meg E. Plomondon, Thomas M. Maddox, Emily J. Marshall, Elizabeth L. Nichols, Michael E. Matheny, Thomas T. Tsai, John S. Rumsfeld, Richard E. Lee, Mark J. Sarnak

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Key issues for stakeholder engagement in the development of health and healthcare guidelines by Jennifer Petkovic, Olivia Magwood, Lyubov Lytvyn, Joanne Khabsa, Thomas W. Concannon, Vivian Welch, Alex Todhunter-Brown, Marisha E. Palm, Elie A. Akl, Lawrence Mbuagbaw, Thurayya Arayssi, Marc T. Avey, Ana Marusic, Richard Morley, Michael Saginur, Nevilene Slingers, Ligia Texeira, Asma Ben Brahem, Soumyadeep Bhaumik, Imad Bou Akl, Sally Crowe, Laura Dormer, Comfort Ekanem, Eddy Lang, Behrang Kianzad, Tanja Kuchenmüller, Lorenzo Moja, Kevin Pottie, Holger Schünemann, Peter Tugwell

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Trends in Veno‐Arterial Extracorporeal Life Support With and Without an Impella or Intra‐Aortic Balloon Pump for Cardiogenic Shock by Michael J. Hendrickson, Vardhmaan Jain, Kirtipal Bhatia, Christopher Chew, Sameer Arora, Joseph S. Rossi, Pedro Villablanca, Navin K. Kapur, Aditya A. Joshi, Arieh Fox, Kiran Mahmood, Edo Y. Birati, Mark J. Ricciardi, Arman Qamar

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Clerkship director confidence in medical student career advising in obstetrics and gynecologyAJOG Global Reports at a Glance by Shireen Madani Sims, MD, Susan M. Cox, MD, Rashmi Bhargava, MD, Elise N. Everett, MD, Angela Fleming, DO, Scott Graziano, MD, MS, Helen K. Morgan, MD, Laura Baecher-Lind, MD, MPH, Celeste Royce, MD, Tammy S. Sonn, MD, Jill M. Sutton, MD, Christopher M. Morosky, MD, MS

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The association of education and household income with the lifetime risk of incident atrial fibrillation: The Framingham Heart study by Feven Ataklte, Quixi Huang, Jelena Kornej, Favel Mondesir, Emelia J Benjamin, Ludovic Trinquart

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Empathy among Saudi Residents at a Tertiary Academic Center during the COVID-19 Pandemic and Its Association with Perceived Stress by Haytham I. AlSaif, Mamdouh N. Alenezi, Mohammed Asiri, Khalid O. Alshaibani, Abdullah A. Alrasheed, Saad M. Alsaad, Mohammed A. Batais

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HIV Drug Resistance in Adults Initiating or Reinitiating Antiretroviral Therapy in Uruguay—Results of a Nationally Representative Survey, 2018–2019 by Rosa Flieller, Susana Cabrera, Dora Ruchansky, Amalia Girón-Callejas, María Brasesco, Daniel Pérez, Héctor Chiparelli, Claudia García-Morales, Daniela Tapia-Trejo, Jessica Monreal-Flores, Giovanni Ravasi, Michael R. Jordan, Santiago Ávila-Ríos

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Prevalence of Emergent Dolutegravir Resistance Mutations in People Living with HIV: A Rapid Scoping Review by Carolyn Chu, Kaiming Tao, Vinie Kouamou, Ava Avalos, Jake Scott, Philip M. Grant, Soo-Yon Rhee, Suzanne M. McCluskey, Michael R. Jordan, Rebecca L. Morgan, Robert W. Shafer

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Obstetrics and gynecology clerkship directors’ experiences advising residency applicantsAJOG Global Reports at a Glance by Helen K. Morgan, MD, Laura Baecher-Lind, MD, MPH, Rashmi Bhargava, MD, Susan Cox, MD, Elise Everett, MD, Angela Fleming, DO, Scott Graziano, MD, MS, Chris Morosky, MD, MS, Celeste Royce, MD, Tammy Sonn, MD, Jill Sutton, MD, Shireen Madani Sims, MD

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Autologous Homologous Skin Constructs Allow Safe Closure of Wounds: A Retrospective, Noncontrolled, Multicentered Case Series by Gerhard S. Mundinger, MD, David G. Armstrong, DPM, MD, PhD, David J. Smith, MD, Alexander M. Sailon, MD, Abhishek Chatterjee, MD, MBA, Greg Tamagnini, DPM, Joanna Partridge, MD, Nicholas Baetz, PhD, Pratima Labroo, PhD, Edward W. Swanson, MD, Nikolai A. Sopko, MD, PhD, Mark S. Granick, MD

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Beat osteoporosis — nourish and exercise skeletons (BONES): a group randomized controlled trial in children by Christina D. Economos, Erin Hennessy, Kenneth Chui, Johanna Dwyer, Lori Marcotte, Aviva Must, Elena N. Naumova, Jeanne Goldberg

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The economic and humanistic burden of bipolar disorder in adults in the United States by Carole Dembek, deMauri Mackie, Kushal Modi, Yingying Zhu, Xiaoli Niu, Todd Grinnell

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ADAM8 is expressed widely in breast cancer and predicts poor outcome in hormone receptor positive, HER-2 negative patients by Stefania Pianetti, Kathy D. Miller, Hannah H. Chen, Sandra Althouse, Sha Cao, Steven J. Michael, Gail E. Sonenshein, Nora D. Mineva

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IMPAHCT: A randomized phase 2b/3 study of inhaled imatinib for pulmonary arterial hypertension by Hunter Gillies, Murali M. Chakinala, Benjamin T. Dake, Jeremy P. Feldman, Marius M. Hoeper, Marc Humbert, Zhi‐Cheng Jing, Jonathan Langley, Vallerie V. McLaughlin, Ralph W. Niven, Stephan Rosenkranz, Xiaosha Zhang, Nicholas S. Hill

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Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies by Max Topp, Monika Dlugosz-Danecka, Aleksander B. Skotnicki, Galina Salogub, Andreas Viardot, Andreas K. Klein, Georg Hess, Christian S. Michel, Sebastian Grosicki, Alex Gural, Sylvia E. Schwarz, Kerstin Pietzko, Ulrike Gärtner, András Strassz, Leila Alland, Jiri Mayer

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A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin by Goldwater R, Kramer WG, Hamilton DA, Lang E, Wang J, Madden DE, Lacouture PG, Ramaiya A, Carr DB

“…Ronald Goldwater,1 William G Kramer,2 Douglas A Hamilton,3,4 Eric Lang,4,5 Jianyuan Wang,4 Donna E Madden,4 Peter G Lacouture,6,7 Atulkumar Ramaiya,8 Daniel B Carr4,9 1PAREXEL International, Baltimore, MD, 2Kramer Consulting, LLC, North Potomac, MD, 3New Biology Ventures, LLC, San Mateo, CA, 4Javelin Pharmaceuticals, Cambridge, MA (now Hospira, a Pfizer company, Lake Forest, IL, USA), 5Covance, Princeton, NJ, 6Magidom Discovery, LLC, Lindenhurst, IL, 7Brown University School of Medicine, Providence, RI, 8Global Medical Affairs, Hospira, a Pfizer company, Lake Forest, IL, 9Department of Anesthesiology, Tufts Medical Center, Boston, MA, USA Purpose: The analgesic and opioid-sparing effects of nonsteroidal anti-inflammatory drugs can be beneficial in postoperative populations. …”
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The tryptophan catabolite or kynurenine pathway in major depressive and bipolar disorder: A systematic review and meta-analysis by Abbas F. Almulla, Yanin Thipakorn, Asara Vasupanrajit, Ali Abbas Abo Algon, Chavit Tunvirachaisakul, Ashwan Abdulzahra Hashim Aljanabi, Gregory Oxenkrug, Hussein K. Al-Hakeim, Michael Maes

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Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights by Randolph J. Noelle, Randolph J. Noelle, J. Louise Lines, Lionel D. Lewis, Robert E. Martell, Robert E. Martell, Thierry Guillaudeux, Sam W. Lee, Kathleen M. Mahoney, Kathleen M. Mahoney, Matthew D. Vesely, Jerome Boyd-Kirkup, Dhanya K. Nambiar, Andrew M. Scott, Andrew M. Scott

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