Identification of Head and Neck Cancer Subtypes Based on Human Papillomavirus Presence and E2F-Regulated Gene Expression by Molly E. Johnson, Paul G. Cantalupo, James M. Pipas

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The Effect of 5-Aza-2′-Deoxycytidine in Combination to and in Comparison with Vorinostat on DNA Methyltransferases, Histone Deacetylase 1, Glutathione S-Transferase 1 and Suppresso... by Masumeh Sanaei, Fraidoon Kavoosi, Zahra Esmi

Subjects: “…Epi-drugs; Tumor suppressor genes; Cancer…”
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High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly Chileans by Hugo Sanchez, Mohammad B. Hossain, Lydia Lera, Sandra Hirsch, Cecilia Albala, Ricardo Uauy, Karin Broberg, Ana M. Ronco

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The role of histone deacetylases in human gastrointestinal and associated glands cancer by Masumeh Sanaei, Fraidoon Kavoosi

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Next-Generation Sequencing Analysis of CpG Methylation of a Tumor Suppressor Gene SHP-1 Promoter in Stable Cell Lines and HCV-Positive Patients by Priya Devi, Katarina Engdahl, Tanel Punga, Anders Bergqvist

“…In this study, we established a next-generation bisulfite sequencing (NGS-BS) protocol to analyze the CpG methylation profile at the tumor suppressor gene SHP-1 P2 promoter as a model system. …”
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Cepharanthine as a Potential Novel Tumor-Regional Therapy in Treating Cutaneous Melanoma: Altering the Expression of Cathepsin B, Tumor Suppressor Genes and Autophagy-Related Proteins by Yufang Liu, Yang Xie, Yao Lin, Qingfang Xu, Yunfen Huang, Mengran Peng, Wei Lai, Yue Zheng

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Exosomal miRNA-21 from Toxoplasma gondii-infected microglial cells induces the growth of U87 glioma cells by inhibiting tumor suppressor genes by Bong-Kwang Jung, Hyemi Song, Hyejoo Shin, Jong-Yil Chai

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Insight into Codon Utilization Pattern of Tumor Suppressor Gene EPB41L3 from Different Mammalian Species Indicates Dominant Role of Selection Force by Utsang Kumar, Rekha Khandia, Shailja Singhal, Nidhi Puranik, Meghna Tripathi, Atul Kumar Pateriya, Raju Khan, Talha Bin Emran, Kuldeep Dhama, Ashok Munjal, Taha Alqahtani, Ali M. Alqahtani

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Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer. by Mariyam Zuberi, Imran Khan, Rashid Mir, Gauri Gandhi, Prakash Chandra Ray, Alpana Saxena

“…MicroRNAs (miRNAs) have been found to be dysregulated in epithelial ovarian cancer (EOC) and may function as either tumor suppressor genes (TSGs) or as oncogenes. Hypermethylation of miRNA silences the tumour suppressive function of a miRNA or hypermethylation of a TSG regulating that miRNA (or vice versa) leads to its loss of function. …”
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The Role and Antagonistic Effects of miR-16-5p in the Regulation of ADP-Ribosylation Factor-Like Tumor Suppressor Gene 1 in Lung Cancer Cells by Tuğba Nurcan Yüksel, Esra Bozgeyik, İbrahim Bozgeyik

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The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type by Toru Uyama, Jun Morishita, Xing-Hua Jin, Yasuo Okamoto, Kazuhito Tsuboi, Natsuo Ueda

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MiR-21 plays an Important Role in Radiation Induced Carcinogenesis in BALB/c Mice by Directly Targeting the Tumor Suppressor Gene Big-h3 by Cong Liu, Bailong Li, Ying Cheng, Jing Lin, Jun Hao, Shuyu Zhang, R.E.J. Mitchel, Ding Sun, Jin Ni, Luqian Zhao, Fu Gao, Jianming Cai

“…In particular, the miRNAs that participates in radiation induced carcinogenesis and the miRNAs that target the tumor suppressor gene Big-h3 remain undefined. Here in this study, using a radiation induced thymic lymphoma model in BALB/c mice, we found that the tumor suppressor gene Big-h3 is down-regulated and miR-21 is up-regulated in radiation induced thymic lymphoma tissue samples. …”
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Gastric Xanthelasma, Microsatellite Instability and Methylation of Tumor Suppressor Genes in the Gastric Mucosa: Correlation and Comparison as a Predictive Marker for the Development of Synchronous/Metachronous Gastric Cancer by Masashi Fukushima, Hirokazu Fukui, Jiro Watari, Chiyomi Ito, Ken Hara, Hirotsugu Eda, Toshihiko Tomita, Tadayuki Oshima, Hiroto Miwa

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A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma by Zhou Yun, Zhang Chun-peng, Li Xiao-yan, Li Yuan-yuan, Li Lin-wei, Lu Shih-Hsin

“…ECRG4 has been described as a novel tumor suppressor gene associated with prognosis in esophageal squamous cell carcinoma (ESCC).…”
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Identification and Validation of Potentially Clinically Relevant CpG Regions within the Class 2 Tumor Suppressor Gene <i>SFRP1</i> in Pancreatic Cancer by Maximilian Hauschulz, Sophia Villwock, Jennifer Kosinski, Florian Steib, Lara Rosaline Heij, Jan Bednarsch, Ruth Knüchel-Clarke, Edgar Dahl

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`In Situ Hybridization for Detection of Latent Epstein-Barr Virus Early Repeats(EBERS) and Mutant-P53- Tumor Suppressor Gene in Patients with Non- Hodgkins Lymphoma by Saad H. Mohammed Ali, Salim R. Hammodi, Amir H. Abdul Amir

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Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma by Yuesheng Jin, Fredrik Mertens, Carl-Magnus Kullendorff, loannis Panagopoulos

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PADI3 induces cell cycle arrest via the Sirt2/AKT/p21 pathway and acts as a tumor suppressor gene in colon cancer by Xiaotian Chang, Zhengbin Chai, Jiaorui Zou, Hongxing Wang, Yao Wang, Yabing Zheng, Hui Wu, Chunyan Liu

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NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer. by Sheng-Tai Tzeng, Ming-Hong Tsai, Chi-Long Chen, Jing-Xing Lee, Tzu-Ming Jao, Sung-Liang Yu, Sou-Jhy Yen, Ya-Chien Yang

“…A novel candidate tumor suppressor gene, namely NDST4, was identified at 4q26. …”
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The diagnostic value of has_circ_0006423 in non-small cell lung cancer and its role as a tumor suppressor gene that sponges miR-492 by Linwen Zhu, Lebo Sun, Guodong Xu, Jie Song, Bingchuan Hu, Zhongjie Fang, Yanggang Dan, Ni Li, Guofeng Shao

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