Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes by Athar Khalil, Batoul Dekmak, Fouad Boulos, Jake Kantrowitz, Avrum Spira, Junya Fujimoto, Humam Kadara, Humam Kadara, Nehme El-Hachem, Georges Nemer

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Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG by Giulia Lombardi, Roberta Valeria Latorre, Alessandro Mosca, Diego Calvanese, Luisa Tomasello, Christian Boni, Manuela Ferracin, Massimo Negrini, Nader Al Dewik, Mohamed Yassin, Mohamed A. Ismail, Bruno Carpentieri, Claudio Sorio, Paola Lecca

“…This study concerns the analysis of the modulation of Chronic Myeloid Leukemia (CML) cell model K562 transcriptome following transfection with the tumor suppressor gene encoding for Protein Tyrosine Phosphatase Receptor Type G (PTPRG) and treatment with the tyrosine kinase inhibitor (TKI) Imatinib. …”
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A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas by Yukiko Nakahara, Hiroshi Ito, Hiroki Namikawa, Takashi Furukawa, Fumitaka Yoshioka, Atsushi Ogata, Jun Masuoka, Tatsuya Abe

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Immunohistochemical phospho tensin tumor suppressor gene staining patterns in endometrial hyperplasias: A 2-year study by Anuradha C. K. Rao, Garima Arya, Priya J Padma

Subjects: “…phospho tensin tumor suppressor gene expression…”
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Identification of oncogenes and tumor-suppressor genes with hepatocellular carcinoma: A comprehensive analysis based on TCGA and GEO datasets by Yue Zhu, Yanfei Wang, Yanfei Wang, Mengyao Hu, Mengyao Hu, Xiaoting Lu, Guoping Sun

“…Beyond a shadow of doubt, the key oncogene PBK and tumor suppressor gene F9 were screened out, and the specific mechanism was investigated through GSEA enrichment analysis and immune correlation analysis. …”
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Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes by Konstantinos Voskarides, Harsh Dweep, Charalambos Chrysostomou

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MiR-107 function as a tumor suppressor gene in colorectal cancer by targeting transferrin receptor 1 by Yuxiang Fu, Liewen Lin, Ligang Xia

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GLAD-PCR assay of DNA methylation sites in regulatory regions of some tumor-suppressor genes in breast cancer by N. A. Smetannikova, M. A. Abdurashitov, A. G. Akishev, P. I. Pozdnyakov, E. V. Dubinin, A. B. Karpov, I. V. Vihlyanov, M. K. Nikitin, S. M. Soldatova, N. A. Netesova

“…Recently, using glad-pcR assay, we have detected aberrantly methylated RcgY sites, which can be considered to be epigenetic markers of colorectal, lung, and gastric cancers. in breast cancer, methylation of the regulatory regions of ALX4, BMP2, CCND2, CDH13, CDX1, FOXA1, GALR1, GATA5, GREM1, HIC1, HMX2, HS3ST2, HOXC10, ICAM5, LAMA1, RARB, RASSF1A, RUNX3, RXRG, RYR2, SFRP2, SOX17, TERT, and ZNF613 tumor-suppressor genes is reported. in the present work, we determined aberrantly methylated RcgY sites in the regulatory regions of these genes in dNa preparations from breast cancer tissues. the study of dNa samples from 30 tumor and 22 normal mammary tissue samples demonstrates a high diagnostic potential of selected R(5mc)gY sites in regulatory regions of CCND2, BMP2, GALR1, SOX17, HMX2, and HS3ST2 genes with total index of sensitivity and specificity for R(5mc)gY detection in tumor dNa 90.0 % and 100.0 %, respectively.…”
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Bioinformatics analysis and identification of upregulated tumor suppressor genes associated with suppressing colon cancer progression by curcumin treatment by Dan Wu, Zhenkai Fu, Wenna Liu, Yujia Zhao, Wenxuan Li, Qingqing Liu, Ying Liang

Subjects: “…tumor suppressor genes…”
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KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration by Chen X, Wang P, Ou T, Li J

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Commentary: The Unliganded Glucocorticoid Receptor Positively Regulates the Tumor Suppressor Gene BRCA1 through GABP Beta by Hanan ePolansky, Adrian eJavaherian

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Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization. by Seung-Beom Hong, HyoungBin Oh, Vladimir A Valera, Masaya Baba, Laura S Schmidt, W Marston Linehan

“…<h4>Background</h4>Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. …”
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ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes by Gi-Cheon Kim, Gi-Cheon Kim, Choong-Gu Lee, Ravi Verma, Dipayan Rudra, Taemook Kim, Keunsoo Kang, Jong Hee Nam, Young Kim, Sin-Hyeog Im, Sin-Hyeog Im, Ho-Keun Kwon, Ho-Keun Kwon, Ho-Keun Kwon

“…ETS1 has shown dichotomous roles as an oncogene and a tumor suppressor gene in diverse cancers, but its functionality in breast cancer tumorigenesis still remains unclear. …”
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Detection of mutations within exons 4 to 8 of the p53 tumor suppressor gene in canine mammary glands by D.M.B. Souza, M.G.O. Barros, J.S.C. Silva, M.B. Silva, Z.F. Coleto, G.C. Jimenez, M. Adrião, A. Wischral

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Creating a mouse model of neurofibromatosis type I : pathological and functional analysis of a tumor suppressor gene by Shih, T. Shane (Tzeshan Shane), 1969-

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Functional Identification of Tumor Suppressor Genes Through an in vivo RNA Interference Screen in a Mouse Lymphoma Model by Bric, Anka, Miething, Cornelius, Bialucha, Carl Uli, Scuoppo, Claudio, Zender, Lars, Krasnitz, Alexander, Xuan, Zhenyu, Zuber, Johannes, Wigler, Michael, Hicks, James, McCombie, Richard W., Hemann, Michael, Hannon, Gregory J., Powers, Scott, Lowe, Scott W.

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Molecular genetic analysis of phosphatase and tensin homolog and p16 tumor suppressor genes in patients with malignant glioma by Abdullah, Jafri Malin, Zainuddin, Norafiza, Sulong, Sarina, Isa, Mohd. Nizam, Jaafar, Hasnan

“…Several genes have been shown to carry mutations in human malignant gliomas, including the phosphatase and tensin homolog (PTEN) deleted on chromosome 10 and p16 tumor suppressor genes. Alterations of this gene located on chromosome 10 q23 and 9p21, respectively, may contribute to gliomagenesis. …”
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LOCALIZATION OF A TUMOR-SUPPRESSOR GENE CAUSING PARATHYROID TUMORS TO CHROMOSOME-1P34-P36 by Williamson, C, Pannett, A, Pang, J, Mccarthy, M, Monson, J, Thakker, R

Genome-Wide Methylation Mapping Using Nanopore Sequencing Technology Identifies Novel Tumor Suppressor Genes in Hepatocellular Carcinoma by Colin F. Davenport, Tobias Scheithauer, Alessia Dunst, Frauke Sophie Bahr, Marie Dorda, Lutz Wiehlmann, Doan Duy Hai Tran

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Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer by N.A. Smetannikova, A.A. Evdokimov, N.A. Netesova, M.A. Abdurashitov, A.G. Akishev, E.V. Dubinin, P.I. Pozdnyakov, I.V. Vihlyanov, M.K. Nikitin, E.B. Topolnitsky, A.B. Karpov, S.A. Kolomiets, S.Kh. Degtyarev

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