Estimating heat-related mortality in near real time for national heatwave plans by Y T Eunice Lo, Dann M Mitchell, Ross Thompson, Emer O’Connell, Antonio Gasparrini

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Research on Antimicrobial Utilization and Resistance in England 2021–22 (ESPAUR Report) by Emily Agnew, Julie V. Robotham

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Influence of SARS-CoV-2 surveillance outputs produced by the UK health security agency (UKHSA) outbreak surveillance team on decision-making by local stakeholders by Katriina Willgert, Jo Hardstaff, Stephanie Shadwell, Alex Bhattacharya, Paula Blomquist, Roberto Vivancos, Ian Simms

“…Abstract Background The UK Health Security Agency (UKHSA) COVID-19 Outbreak Surveillance Team (OST) was established in June 2020 to provide Local Authorities (LAs) in England with surveillance intelligence to aid their response to the SARS-CoV-2 epidemic. …”
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Publisher Correction: Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)2 fragments by Stephen Findlay‑Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Matthew Aldridge, Gareth Humphries, Holger Schuhmann, Didier Ngabo, Emma Rayner, Ashley Otter, Thomas Coleman, Bethany Hicks, Rachel Halkerston, Kostis Apostolakis, Stephen Taylor, Susan Fotheringham, Amanda Horton, Irene CanoCejas, Matthew Wand, Julia A. Tree, Mark Sutton, Victoria Graham, Roger Hewson, Stuart Dowall

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Author Correction: Serological responses and vaccine effectiveness for extended COVID-19 vaccine schedules in England by Gayatri Amirthalingam, Jamie Lopez Bernal, Nick J. Andrews, Heather Whitaker, Charlotte Gower, Julia Stowe, Elise Tessier, Sathyavani Subbarao, Georgina Ireland, Frances Baawuah, Ezra Linley, Lenesha Warrener, Michelle O’Brien, Corinne Whillock, Paul Moss, Shamez N. Ladhani, Kevin E. Brown, Mary E. Ramsay

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Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)2 fragments by Stephen Findlay-Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Matthew Aldridge, Gareth Humphries, Holger Schuhmann, Didier Ngabo, Emma Rayner, Ashley Otter, Thomas Coleman, Bethany Hicks, Rachel Halkerston, Kostis Apostolakis, Stephen Taylor, Susan Fotheringham, Amanda Horton, Irene CanoCejas, Matthew Wand, Julia A. Tree, Mark Sutton, Victoria Graham, Roger Hewson, Stuart Dowall

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Detection of SARS-CoV-2 BA.2.86 by lateral flow devices by Abbie Bown, Angela Sweed, Matthew Catton, Joshua Nelthorpe-Cowne, Hermione Conti-Frith, Ruth Elderfield, Jacob Terrey, Hamsa Abib, Caleb Lui, Ella Fisher, Kevin R. Bewley, Naomi S. Coombes, Donna Robinson, Somya Agrawal, Bassam Hallis, Edward Blandford, Tom Fowler, Deborah A. Williamson, Richard Vipond

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Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals by Ashley D. Otter, Scott Jones, Bethany Hicks, Daniel Bailey, Helen Callaby, Catherine Houlihan, Tommy Rampling, Nicola Claire Gordon, Hannah Selman, Panayampalli S. Satheshkumar, Michael Townsend, Ravi Mehta, Marcus Pond, Rachael Jones, Deborah Wright, Clarissa Oeser, Simon Tonge, Ezra Linley, Georgia Hemingway, Tom Coleman, Sebastian Millward, Aaron Lloyd, Inger Damon, Tim Brooks, Richard Vipond, Cathy Rowe, Bassam Hallis

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Severity of COVID-19 sub-lineages XBB/XBB 1.5/XBB1.16, EG.5.1. and JN.1. in England by Catherine Quinot, Freja Kirsebom, Nick Andrews, Julia Stowe, Mary Ramsay, Gavin Dabrera, Meaghan Kall, Jamie Lopez Bernal, Alex Allen

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Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme by Matthias E. Futschik, Raghavendran Kulasegaran-Shylini, Edward Blandford, Sean Harper, David Chapman, Elena Turek, Somya Agrawal, Valerie Phillips, Hannah Fordham, Lee Chan, Mike Kidd, Andrew Dodgson, Paul E. Klapper, Malur Sudhanva, Richard Vipond, Susan Hopkins, Tim Peto, Sarah Tunkel, Tom Fowler

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Author Correction: Forecasting influenza hospital admissions within English sub-regions using hierarchical generalised additive models by Jonathon Mellor, Rachel Christie, Christopher E. Overton, Robert S. Paton, Rhianna Leslie, Maria Tang, Sarah Deeny, Thomas Ward

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A cross-sectional national investigation of COVID-19 outbreaks in nurseries during rapid spread of the Alpha (B.1.1.7) variant of SARS-CoV-2 in England by Felicity Aiano, Kelsey McOwat, Chinelo Obi, Annabel A. Powell, Jessica Flood, Shivraj Bhardwaj, Kelly Stoker, Donna Haskins, Brian Wong, Marta Bertran, Maria Zavala, Johanna Bosowski, Samuel E. I. Jones, Zahin Amin-Chowdhury, Laura Coughlan, Mary Sinnathamby, Asad Zaidi, Rachel Merrick, Hongxin Zhao, Sharif Ismail, Mary E. Ramsay, Shamez N. Ladhani, Vanessa Saliba

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Impact of prior SARS-CoV-2 infection and COVID-19 vaccination on the subsequent incidence of COVID-19: a multicentre prospective cohort study among UK healthcare workers – the SIRE... by Nick Andrews, Mary Ramsay, Maria Zambon, Victoria Hall, Sarah Wallace, Susan Hopkins, Jean Timeyin, Tim J G Brooks, Amoolya Vusirikala, Meera Chand, Andre Charlett, Sakib Rokadiya, Colin S Brown, Madhumita Shrotri, Peter D Kirwan, Michele Cole, Natalie Gillson, Ana Atti, Sarah Foulkes, Andrew Taylor-Kerr, Blanche Oguti, Jasmin Islam

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Foodborne Outbreak of Extended Spectrum Beta-lactamase Producing Shigella sonnei Associated with Contaminated Spring Onions in the United Kingdom by Claire Jenkins, Philippa Griffith, Ann Hoban, Claire Brown, Joanna Garner, Megan Bardsley, Caroline Willis, Frieda Jorgensen, Matthew Bird, David R. Greig, Matt Edmunds, Charles Beck, Lesley Larkin

“…In November 2021, the UK Health Security Agency detected an outbreak of 17 cases infected with the same strain of MDR extended spectrum beta-lactamase (ESBL)-producing Shigella sonnei. …”
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Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques by Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe

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Faster detection of asymptomatic COVID-19 cases among care home staff in England through the combination of SARS-CoV-2 testing technologies by Finola Ryan, Joanna Cole-Hamilton, Niharika Dandamudi, Matthias E. Futschik, Alexander Needham, Rida Saquib, Raghavendran Kulasegaran-Shylini, Edward Blandford, Michael Kidd, Éamonn O’Moore, Ian Hall, Malur Sudhanva, Paul Klapper, Andrew Dodgson, Adam Moore, Madeleine Duke, Sarah Tunkel, Chris Kenny, Tom Fowler

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SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum by Alastair Handley, Kathryn A. Ryan, Elizabeth R. Davies, Kevin R. Bewley, Oliver T. Carnell, Amy Challis, Naomi S. Coombes, Susan A. Fotheringham, Karen E. Gooch, Michael Charlton, Debbie J. Harris, Chelsea Kennard, Didier Ngabo, Thomas M. Weldon, Francisco J. Salguero, Simon G. P. Funnell, Yper Hall

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National Antimicrobial Stewardship Activities in Primary and Secondary Care in England 2021–22 (ESPAUR Report) by Ella Casale, Catherine V. Hayes, Donna Lecky, Luke O’Neil, Eirwen Sides, Emily Cooper, Fionna Pursey, Sejal Parekh, Eleanor J. Harvey, Diane Ashiru-Oredope

“…A summary of key national primary and secondary care antimicrobial stewardship interventions led by the UK Health Security Agency (UKHSA) are highlighted. This includes development and implementation of TARGET Antibiotics Toolkit resources in community pharmacy and General Practice and the development of a national intravenous-to-oral switch (IVOS) criteria for use in secondary care.…”
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Effectiveness of ChAdOx1-S COVID-19 booster vaccination against the Omicron and Delta variants in England by Freja Cordelia Møller Kirsebom, Nick Andrews, Ruchira Sachdeva, Julia Stowe, Mary Ramsay, Jamie Lopez Bernal

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An analysis of 45 large-scale wastewater sites in England to estimate SARS-CoV-2 community prevalence by Mario Morvan, Anna Lo Jacomo, Celia Souque, Matthew J. Wade, Till Hoffmann, Koen Pouwels, Chris Lilley, Andrew C. Singer, Jonathan Porter, Nicholas P. Evens, David I. Walker, Joshua T. Bunce, Andrew Engeli, Jasmine Grimsley, Kathleen M. O’Reilly, Leon Danon

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